Game and Fish Begins Study to Evaluate Chronic Wasting Disease Vaccine
2/19/2013
CHEYENNE - The Wyoming Game and Fish Department has begun a multi-year
study at its Thorne-Williams Wildlife Research Unit (formerly Sybille) near
Wheatland to evaluate the efficacy of a vaccine against chronic wasting disease.
Chronic wasting disease is a neurological disease of elk, deer, and moose.
The disease appears to be invariably fatal to the animal, but it is not thought
to affect humans.
The vaccine was developed in Canada by the Pan-Provincial Vaccine
Enterprise (PREVENT), a partnership of three leading infectious disease centers.
PREVENT works closely with academia, industry, government, and not-for-profit
sectors to accelerate vaccine development so that promising vaccines can move
readily into clinical development and production.
In January, researchers trapped 50 elk calves at Game and Fish’s South Park
feedground (south of Jackson) and transported them to the research unit. There,
calves were split into two groups. One group was vaccinated and one was an
unvaccinated control group. “Previous research has demonstrated that elk will
naturally contract chronic wasting disease by being housed at the unit,” said
Game and Fish Chief Wildlife Veterinarian Dr. Terry Kreeger. “We predict that
the vaccinated group will live longer than the control group. It’s important to
understand that even if the vaccine does not provide lifelong protection from
chronic wasting disease, every extra year of survival the vaccine provides will
mean increased production in an affected population.”
The vaccine is administered by hand at the research unit, which would not
be practical for vaccinating wild elk. However, if the vaccine is found to be
effective, future research will focus on delivery methods more appropriate for
wild elk, such as baits. At a minimum, an effective vaccine administered to elk
raised on private ranches could greatly reduce the spread of the disease.
Chronic wasting disease is thought to have been primarily spread throughout
parts of the United States and Canada by the unintentional movement of infected
deer and elk among private game ranches.
“We figured that research over time would start providing wildlife managers
with tools that could be used to combat this disease,” said Kreeger. “This is
just the start of a long journey to evaluate and perfect these tools.”
A parallel vaccine study is being conducted on deer in Colorado.
(Contact: Eric Keszler (307) 777-4594)
-WGFD-
CWD Zones Map for Positive Cases
All Species Positive & Negative (Updated with 2012 Data)
Positives by Species (Updated with 2012 Data)
Positives by Species (2009-2011)
CWD Surveillance Positive Deer
Positive Deer by Hunt Area (2012)
Positive Deer by Hunt Area (2009-2011)
Positive Deer by Hunt Area (2006-2008)
Positive Deer by Hunt Area (2003-2005)
CWD Surveillance Positive Elk
Positive Elk by Hunt Area (2012)
Positive Elk by Hunt Area (2009-2011)
Positive Elk by Hunt Area (2006-2008)
Positive Elk by Hunt Area (2003-2005)
CWD Surveillance Positive Moose
Positive Moose by Hunt Area (2006-2008)
WYOMING GAME AND FISH DEPARTMENT 2011 ANNUAL REPORT
SNIP...
CHRONIC WASTING DISEASE CWD
Chronic Wasting Disease Testing continued for Chronic Wasting Disease (CWD)
in white-tailed and mule deer, elk, and moose in various locations of the state.
WGFD divides the state into eight administrative regions with the goal to test
500-600 deer from each region utilizing hunter harvest, road killed, and
targeted animals. Although the 2011 surveillance efforts are still underway, as
of December 1st, 2,911 deer, elk, and moose samples had been analyzed. Of these,
103 tested positive for CWD, representing 79 mule deer, 14 white-tailed deer,
and 10 elk. In 2005, the Department included moose in the CWD surveillance
program. During FY 2011, 136 hunter-killed, 37 targeted and 18 road-killed moose
were surveyed with no moose testing positive for CWD.
MOOSE DOCUMENTED WITH CWD WYOMING
Wednesday, October 24, 2012
WYOMING Deer Hunt Area 132 Near Green River Added to CWD List
10/23/2012
GREEN RIVER - Chronic wasting disease (CWD), a fatal neurological disease
of deer, elk, and moose, has been discovered in deer hunt area 132.
Thursday, November 29, 2012
Wyoming Elk Hunt Area 10 Added to CWD List
Wednesday, November 16, 2011
Chronic wasting disease found in Big Horn basin deer Wyoming's deer hunt
area 165
Thursday, July 08, 2010
CWD Controversy still stalking elk feedgrounds in Wyoming 2010
Greetings,
This is very serious, please notice that one of the CWD clusters is only 45
miles from ELK feeding grounds in Wyoming, the second elk feeding ground is 98
miles from CWD cluster, and the third elk feeding ground is 130 miles from the
CWD cluster. Common sense tells us we need to stop those feeding grounds, if you
want your Elk to survive. There is no politics or plot against the hunters or
elk about it. read the science please. ...TSS
chronic wasting disease proximity to elk feedgrounds in wyoming
2009-2010
Thursday, December 30, 2010
WYOMING MULE DEER BUCK HARVESTED NEAR LYSITE TESTS POSITIVE FOR CWD
December 27, 2010
Monday, December 13, 2010
WYOMING DEER AREA 119 ADDED TO CWD LIST DEER AREA 119 ADDED TO CWD
LIST
11/22/2010
Friday, November 12, 2010
WHITE-TAILED BUCK HARVESTED NEAR MOORCROFT TESTS POSITIVE FOR CWD
WYOMING
Sunday, October 31, 2010
TWO DEER HARVESTED NEAR GREYBULL TEST POSITIVE FOR CWD WYOMING
Wednesday, October 20, 2010
WYOMING ELK NEAR GLENDO TESTS POSITIVE FOR CWD 10/18/2010
Wednesday, November 25, 2009
CHRONIC WASTING DISEASE FOUND IN ELK AREA 35 NEAR BUFFALO
Wednesday, November 11, 2009
CHRONIC WASTING DISEASE DISCOVERED IN DEER HUNT AREA 42 WYOMING
Sunday, November 01, 2009
CWD confirmed in Johnson County Wyoming Sunday, November 1, 2009
Wednesday, October 14, 2009
Deer on western Bighorns has chronic wasting disease Shell Creek drainage
Wyoming
Monday, December 22, 2008
CWD DETECTED IN ELK HUNT AREA 117 SOUTH OF SUNDANCE WYOMING
Saturday, October 18, 2008
WYOMING STAR VALLEY MOOSE TESTS POSITIVE FOR CWD
Monday, November 14, 2011
WYOMING Creutzfeldt Jakob Disease, CWD, TSE, PRION REPORTING 2011
Friday, November 09, 2012
Chronic Wasting Disease CWD in cervidae and transmission to other species
Friday, November 16, 2012
Yellowstone elk herds feeding grounds, or future killing grounds from CWD
Tuesday, February 28, 2012
newly developed injectable CWD vaccine, live rectal mucosa testing and Deer
Game Farms Update newly developed injectable CWD vaccine, live rectal mucosa
testing and Deer Game Farms Update
- testing is currently underway to determine the effectiveness of a newly
developed injectable CWD vaccine that has shown considerable promise.
- an effective vaccine could be used to prevent CWD in game farm animals
but additional study would be required to determine an effective application
method in the wild.
snip...see full text ;
Development of an oral vaccine for Chronic Wasting Disease
Principal Investigator: Scott Napper, Vaccine and Infectious Disease
Organization
Co-investigators: Andrew Potter, Vaccine and Infectious Disease
Organization Philip Griebel, Vaccine and Infectious Disease Organization Neil
Cashman, Brain Research Centre, University of British Columbia Suresh Tikoo,
Vaccine and Infectious Disease Organization Nate Osgood, Computer Sciences,
University of Saskatchewan Trent Bollinger, Western College of Veterinary
Medicine, University of Saskatchewan Ted Leighton, Western College of Veterinary
Medicine, University of Saskatchewan Cheryl Waldner, Western College of
Veterinary Medicine, University of Saskatchewan Murray Woodbury, Western College
of Veterinary Medicine, University of Saskatchewan
Project Description
Members of our team have been focused on a disease specific epitope (DSE)
termed YYR which is specifically exposed on PrPSc. Through optimization of the
length and presentation of this epitope, as well as strategies of formulation
and delivery, we have developed a first generation prion vaccine. This vaccine
was developed with a priority on farmed cervids and employed strategies
compatible with parenteral injection, the traditional route of vaccine delivery.
This vaccine induces high-titre, PrPSc-specific immune responses in a variety of
species and significantly delays the onset of disease in experimentally
challenged sheep. Having validated the DSE immunotherapy concept, we are
positioned to develop a second generation vaccine based upon additional, newly
discovered DSE’s as well as an oral route of delivery. Oral delivery is required
for vaccination of wild animals and is the preferred route for farmed cervids.
Oral delivery may also offer greater protection against oral routes of
infection, which is central to CWD transmission. Funding by PrioNet will enable
and accelerate development of this novel tool to control Chronic Wasting
Disease.
(Open Call IV)
Last Updated: 10/21/2011 4:44:47 PM
SNIP...FULL TEXT ;
Friday, August 24, 2012
Diagnostic accuracy of rectal mucosa biopsy testing for chronic wasting
disease within white-tailed deer (Odocoileus virginianus) herds in North America
Friday, February 08, 2013
Behavior of Prions in the Environment: Implications for Prion Biology
Tuesday, December 18, 2012
A Growing Threat How deer breeding could put public trust wildlife at risk
Friday, November 09, 2012
*** Chronic Wasting Disease CWD in cervidae and transmission to other
species
Friday, December 14, 2012
*** Susceptibility Chronic Wasting Disease (CWD) in wild cervids to Humans
2005 – December 14, 2012
TSS
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