IMPORTANT: Cervid Industry and State Veterinarians on Rewriting Chronic 
Wasting Disease Rule 
USDA Animal and Plant Health Inspection Service sent this bulletin at 
04/01/2013 01:40 PM EDT 
During its regularly scheduled conference call with USDA officials, the 
National Assembly of State Animal Health Officials discussed the progress that 
has been made by the Chronic Wasting Disease (CWD) Program Standards Working 
Group. 
Because members of the working group represent varied interests, it has 
been difficult for the group to reach consensus. 
Further, Federal dollars to support the CWD program have dramatically 
decreased, leaving limited options for managing the program. 
USDA recognizes that producers have continued concerns about the language 
in the program standards and the provisions of the CWD interim final rule. Dr. 
John Clifford, Deputy Administrator, APHIS Veterinary Services, does not support 
withdrawing the rule or developing a separate industry program; however, he 
agreed on the conference call to listen to the concerns of stakeholders. 
*** 
CWD in Farmed Herds
 
The APHIS National CWD Herd Certification Program (HCP) is designed to be a voluntary federal -state- industry cooperative program administered by APHIS and implemented by participating states. The 2012 interim final CWD rule published in the Federal Register on June 13, 2012 addresses the needs of the farmed cervid industry and concerns of State animal health and wildlife partners, and establishes the national voluntary CWD HCP. This program was developed in coordination with States and the farmed cervid industry. States may apply to become an Approved State HCP if they meet (or exceed) national program requirements. Cervid owners can enroll and participate in their Approved State CWD HCP. Based on availability of appropriated funding, APHIS may provide for herd owner enrollment directly in the national program if no Approved State CWD HCP exists in that herd owner's State. National CWD HCP requirements include fencing, individual animal ID's, regular inventories, and testing of all animals over 12 months that die for any reason. With each year of successful surveillance, participating herds will advance in status until reaching five years with no evidence of CWD, at which time herds are certified as being low risk for CWD. Interstate movement of animals will be dependent on participation in the program, maintaining compliance with program requirements, and having achieved herd certification status. A copy of the CWD Program Standards is available for further details on the National CWD HCP.
 
The 2012 interim final rule for the Chronic Wasting Disease Herd Certification Program and Interstate Movement of Farmed or Captive Deer, Elk, and Moose is available through this website link to the Federal Register. Several states already have CWD monitoring or certification programs for captive herds. To find out more about your state's activities related to CWD, visit the State Information page for links to state agriculture agencies or go to the CWD Alliance website at www.cwd-info.org.
 
Summary of Nationwide Chronic Wasting Disease Testing in Farmed/Captive Cervids:
 
Since 1998 samples from farmed/captive cervids have been tested with assistance from APHIS as concerns continued to build for the risk of introduction and transmission of CWD in farmed cervid herds. By mid-2012, 55 cervid herds in 11 States were reported to be CWD positive. View a graph of annual totals of CWD surveillance in farmed/captive cervid herds and a map depicting states with CWD in farmed/captive cervid herds. Listing of Approved State CWD Herd Certification Programs (HCPs)
 
http://www.aphis.usda.gov/animal_health/animal_diseases/cwd/farmed.shtml
 
 
SUMMARY: We are amending a final rule, which will take effect when these amendments become effective, that will establish a herd certification program to control chronic wasting disease (CWD) in farmed or captive cervids in the United States. Under that rule, owners of deer, elk, and moose herds who choose to participate in the CWD Herd Certification Program would have to follow requirements for animal identification, testing, herd management, and movement of animals into and from herds. This document amends that final rule to provide that our regulations will set minimum requirements for the interstate movement of farmed or captive deer, elk, and moose but will not preempt State or local laws or regulations that are more restrictive than our regulations. This document requests public comment on that change. This document also amends the final rule to require farmed or captive deer, elk, and moose to participate in the Herd Certification Program and to be monitored for CWD for 5 years before they can move interstate, clarify our herd inventory procedures, establish an optional protocol for confirmatory DNA testing of CWD-positive samples, add a requirement to continue testing cervids that are killed or sent to slaughter from Certified herds, and make several other changes. These actions will help to control the incidence of CWD in farmed or captive cervid herds and prevent its spread. DATES: Effective Date: This interim final rule is effective August 13, 2012. Additionally, the effective date of FR Doc 06–6367, published on July 21, 2006 (71 FR 41682–41707), and delayed by FR Doc E6–14861, published on September 8, 2006 (71 FR 52983), is now August 13, 2012. Compliance Date:
 
 
 
see full text ;
 
 
http://www.gpo.gov/fdsys/pkg/FR-2012-06-13/pdf/2012-14186.pdf
 
 
 
Chronic Wasting Disease Program Standards July 2012
 
 
Chronic Wasting Disease—Program Standards 1 Introduction These Program Standards will be reviewed at least annually by representatives of the cervid industry and appropriate State and Federal agencies. A notice may be published in the Federal Register to inform stakeholders of any revisions APHIS plans to the Program Standards. These Program Standards also may be amended in the future by replacing pages or by adding new pages. Part A. Herd Certification Program These Program Standards are the minimum standards adopted and approved by the Deputy Administrator, Veterinary Services (VS), Animal and Plant Health Inspection Service (APHIS), United States Department of Agriculture (USDA). They were established for three primary purposes: 1. To assist Federal and State agencies in maintaining CWD-certified herds of deer, elk, and moose (all Odocoileus spp. and Cervus spp. and their hybrids and Alces alces). 2. To provide guidance on procedures to certify herds as a low risk for CWD by remaining in continuous compliance with the CWD Herd Certification Program requirements found in 9 CFR Part 55. 3. To provide guidance on complying with the minimum requirements for interstate movement of cervids found in 9 CFR Part 81. Part B. Guidance on Response to CWD-Affected Herds The CWD regulations at 9 CFR part 55 describe minimum requirements in response to the finding of a CWD-affected herd in accordance with the national CWD HCP. This section further provides suggested best management practices that may be used by a State and herd owner to investigate and manage CWD-affected herds, including quarantine, depopulation, cleaning and decontamination, and herd plans.
 
 
snip...see full text ;
 
 
http://www.aphis.usda.gov/animal_health/animal_diseases/cwd/downloads/cwd_program_standards.pdf
 
 
 
see state CWD programs ;
 
 
http://www.aphis.usda.gov/animal_health/animal_diseases/cwd/stateinfo2.shtml
 
 
 
 
USDA TO PGC ONCE CAPTIVES ESCAPE
 
"it‘s no longer its business.”
 
problem solved $$$...TSS
 
 
Sunday, January 06, 2013
 
USDA TO PGC ONCE CAPTIVES ESCAPE "it‘s no longer its business.”
 
http://chronic-wasting-disease.blogspot.com/2013/01/usda-to-pgc-once-captives-escape-its-no.html
 
 
 
 
 
 
| Voluntary National CWD Herd Certification Program | 
The APHIS National CWD Herd Certification Program (HCP) is designed to be a voluntary federal -state- industry cooperative program administered by APHIS and implemented by participating states. The 2012 interim final CWD rule published in the Federal Register on June 13, 2012 addresses the needs of the farmed cervid industry and concerns of State animal health and wildlife partners, and establishes the national voluntary CWD HCP. This program was developed in coordination with States and the farmed cervid industry. States may apply to become an Approved State HCP if they meet (or exceed) national program requirements. Cervid owners can enroll and participate in their Approved State CWD HCP. Based on availability of appropriated funding, APHIS may provide for herd owner enrollment directly in the national program if no Approved State CWD HCP exists in that herd owner's State. National CWD HCP requirements include fencing, individual animal ID's, regular inventories, and testing of all animals over 12 months that die for any reason. With each year of successful surveillance, participating herds will advance in status until reaching five years with no evidence of CWD, at which time herds are certified as being low risk for CWD. Interstate movement of animals will be dependent on participation in the program, maintaining compliance with program requirements, and having achieved herd certification status. A copy of the CWD Program Standards is available for further details on the National CWD HCP.
The 2012 interim final rule for the Chronic Wasting Disease Herd Certification Program and Interstate Movement of Farmed or Captive Deer, Elk, and Moose is available through this website link to the Federal Register. Several states already have CWD monitoring or certification programs for captive herds. To find out more about your state's activities related to CWD, visit the State Information page for links to state agriculture agencies or go to the CWD Alliance website at www.cwd-info.org.
Summary of Nationwide Chronic Wasting Disease Testing in Farmed/Captive Cervids:
Since 1998 samples from farmed/captive cervids have been tested with assistance from APHIS as concerns continued to build for the risk of introduction and transmission of CWD in farmed cervid herds. By mid-2012, 55 cervid herds in 11 States were reported to be CWD positive. View a graph of annual totals of CWD surveillance in farmed/captive cervid herds and a map depicting states with CWD in farmed/captive cervid herds. Listing of Approved State CWD Herd Certification Programs (HCPs)
|  | 
http://www.aphis.usda.gov/animal_health/animal_diseases/cwd/farmed.shtml
SUMMARY: We are amending a final rule, which will take effect when these amendments become effective, that will establish a herd certification program to control chronic wasting disease (CWD) in farmed or captive cervids in the United States. Under that rule, owners of deer, elk, and moose herds who choose to participate in the CWD Herd Certification Program would have to follow requirements for animal identification, testing, herd management, and movement of animals into and from herds. This document amends that final rule to provide that our regulations will set minimum requirements for the interstate movement of farmed or captive deer, elk, and moose but will not preempt State or local laws or regulations that are more restrictive than our regulations. This document requests public comment on that change. This document also amends the final rule to require farmed or captive deer, elk, and moose to participate in the Herd Certification Program and to be monitored for CWD for 5 years before they can move interstate, clarify our herd inventory procedures, establish an optional protocol for confirmatory DNA testing of CWD-positive samples, add a requirement to continue testing cervids that are killed or sent to slaughter from Certified herds, and make several other changes. These actions will help to control the incidence of CWD in farmed or captive cervid herds and prevent its spread. DATES: Effective Date: This interim final rule is effective August 13, 2012. Additionally, the effective date of FR Doc 06–6367, published on July 21, 2006 (71 FR 41682–41707), and delayed by FR Doc E6–14861, published on September 8, 2006 (71 FR 52983), is now August 13, 2012. Compliance Date:
see full text ;
http://www.gpo.gov/fdsys/pkg/FR-2012-06-13/pdf/2012-14186.pdf
Chronic Wasting Disease Program Standards July 2012
Chronic Wasting Disease—Program Standards 1 Introduction These Program Standards will be reviewed at least annually by representatives of the cervid industry and appropriate State and Federal agencies. A notice may be published in the Federal Register to inform stakeholders of any revisions APHIS plans to the Program Standards. These Program Standards also may be amended in the future by replacing pages or by adding new pages. Part A. Herd Certification Program These Program Standards are the minimum standards adopted and approved by the Deputy Administrator, Veterinary Services (VS), Animal and Plant Health Inspection Service (APHIS), United States Department of Agriculture (USDA). They were established for three primary purposes: 1. To assist Federal and State agencies in maintaining CWD-certified herds of deer, elk, and moose (all Odocoileus spp. and Cervus spp. and their hybrids and Alces alces). 2. To provide guidance on procedures to certify herds as a low risk for CWD by remaining in continuous compliance with the CWD Herd Certification Program requirements found in 9 CFR Part 55. 3. To provide guidance on complying with the minimum requirements for interstate movement of cervids found in 9 CFR Part 81. Part B. Guidance on Response to CWD-Affected Herds The CWD regulations at 9 CFR part 55 describe minimum requirements in response to the finding of a CWD-affected herd in accordance with the national CWD HCP. This section further provides suggested best management practices that may be used by a State and herd owner to investigate and manage CWD-affected herds, including quarantine, depopulation, cleaning and decontamination, and herd plans.
snip...see full text ;
http://www.aphis.usda.gov/animal_health/animal_diseases/cwd/downloads/cwd_program_standards.pdf
see state CWD programs ;
http://www.aphis.usda.gov/animal_health/animal_diseases/cwd/stateinfo2.shtml
USDA TO PGC ONCE CAPTIVES ESCAPE
"it‘s no longer its business.”
problem solved $$$...TSS
Sunday, January 06, 2013
USDA TO PGC ONCE CAPTIVES ESCAPE "it‘s no longer its business.”
http://chronic-wasting-disease.blogspot.com/2013/01/usda-to-pgc-once-captives-escape-its-no.html
Monday, March 18, 2013 
PROCEEDINGS ONE HUNDRED AND FIFTEENTH ANNUAL MEETING of the UNITED STATES 
ANIMAL HEALTH ASSOCIATION September 29 – October 5, 2011 
see updated 2012 RESOLUTIONS 
Friday, December 14, 2012 
DEFRA U.K. What is the risk of Chronic Wasting Disease CWD being introduced 
into Great Britain? A Qualitative Risk Assessment October 2012 
snip... 
In the USA, under the Food and Drug Administration’s BSE Feed Regulation 
(21 CFR 589.2000) most material (exceptions include milk, tallow, and gelatin) 
from deer and elk is prohibited for use in feed for ruminant animals. With 
regards to feed for non-ruminant animals, under FDA law, CWD positive deer may 
not be used for any animal feed or feed ingredients. For elk and deer considered 
at high risk for CWD, the FDA recommends that these animals do not enter the 
animal feed system. However, this recommendation is guidance and not a 
requirement by law. 
Animals considered at high risk for CWD include: 
1) animals from areas declared to be endemic for CWD and/or to be CWD 
eradication zones and 
2) deer and elk that at some time during the 60-month period prior to 
slaughter were in a captive herd that contained a CWD-positive animal. 
Therefore, in the USA, materials from cervids other than CWD positive 
animals may be used in animal feed and feed ingredients for non-ruminants. 
The amount of animal PAP that is of deer and/or elk origin imported from 
the USA to GB can not be determined, however, as it is not specified in TRACES. 
It may constitute a small percentage of the 8412 kilos of non-fish origin 
processed animal proteins that were imported from US into GB in 2011. 
Overall, therefore, it is considered there is a __greater than negligible 
risk___ that (nonruminant) animal feed and pet food containing deer and/or elk 
protein is imported into GB. 
There is uncertainty associated with this estimate given the lack of data 
on the amount of deer and/or elk protein possibly being imported in these 
products. 
snip... 
36% in 2007 (Almberg et al., 2011). In such areas, population declines of 
deer of up to 30 to 50% have been observed (Almberg et al., 2011). In areas of 
Colorado, the prevalence can be as high as 30% (EFSA, 2011). 
The clinical signs of CWD in affected adults are weight loss and 
behavioural changes that can span weeks or months (Williams, 2005). In addition, 
signs might include excessive salivation, behavioural alterations including a 
fixed stare and changes in interaction with other animals in the herd, and an 
altered stance (Williams, 2005). These signs are indistinguishable from cervids 
experimentally infected with bovine spongiform encephalopathy (BSE). 
Given this, if CWD was to be introduced into countries with BSE such as GB, 
for example, infected deer populations would need to be tested to differentiate 
if they were infected with CWD or BSE to minimise the risk of BSE entering the 
human food-chain via affected venison. 
snip... 
The rate of transmission of CWD has been reported to be as high as 30% and 
can approach 100% among captive animals in endemic areas (Safar et al., 2008). 
snip... 
In summary, in endemic areas, there is a medium probability that the soil 
and surrounding environment is contaminated with CWD prions and in a 
bioavailable form. In rural areas where CWD has not been reported and deer are 
present, there is a greater than negligible risk the soil is contaminated with 
CWD prion. 
snip... 
In summary, given the volume of tourists, hunters and servicemen moving 
between GB and North America, the probability of at least one person travelling 
to/from a CWD affected area and, in doing so, contaminating their clothing, 
footwear and/or equipment prior to arriving in GB is greater than negligible. 
For deer hunters, specifically, the risk is likely to be greater given the 
increased contact with deer and their environment. However, there is significant 
uncertainty associated with these estimates. 
snip... 
Therefore, it is considered that farmed and park deer may have a higher 
probability of exposure to CWD transferred to the environment than wild deer 
given the restricted habitat range and higher frequency of contact with tourists 
and returning GB residents. 
snip... 
Friday, December 14, 2012 
DEFRA U.K. What is the risk of Chronic Wasting Disease CWD being introduced 
into Great Britain? A Qualitative Risk Assessment October 2012 
please note, I do not know how much of this 125 TONS of banned mad cow 
protein was part of the ; 
e) "Big Jim's" BBB Deer Ration, Big Buck Blend, Recall # V-104-6; 
bbbut, this was about 10 years post mad cow feed ban from 1997. 10 years 
later, and still feeding banned mad cow protein to cervids??? 
considering that .005 gram is lethal to several bovines, and we know that 
the oral consumption of CWD tainted products is very efficient mode of 
transmission of CWD. 
Subject: MAD COW FEED RECALL AL AND FL VOLUME OF PRODUCT IN COMMERCE 125 
TONS Products manufactured from 02/01/2005 until 06/06/2006 
Date: August 6, 2006 at 6:16 pm PST 
PRODUCT 
a) CO-OP 32% Sinking Catfish, Recall # V-100-6; 
b) Performance Sheep Pell W/Decox/A/N, medicated, net wt. 50 lbs, Recall # 
V-101-6; 
c) Pro 40% Swine Conc Meal -- 50 lb, Recall # V-102-6; 
d) CO-OP 32% Sinking Catfish Food Medicated, Recall # V-103-6; 
***e) "Big Jim's" BBB Deer Ration, Big Buck Blend, Recall # V-104-6; 
f) CO-OP 40% Hog Supplement Medicated Pelleted, Tylosin 100 grams/ton, 50 
lb. bag, Recall # V-105-6; 
g) Pig Starter Pell II, 18% W/MCDX Medicated 282020, Carbadox -- 0.0055%, 
Recall # V-106-6; 
h) CO-OP STARTER-GROWER CRUMBLES, Complete Feed for Chickens from Hatch to 
20 Weeks, Medicated, Bacitracin Methylene Disalicylate, 25 and 50 Lbs, Recall # 
V-107-6; 
i) CO-OP LAYING PELLETS, Complete Feed for Laying Chickens, Recall # 108-6; 
j) CO-OP LAYING CRUMBLES, Recall # V-109-6; 
k) CO-OP QUAIL FLIGHT CONDITIONER MEDICATED, net wt 50 Lbs, Recall # 
V-110-6; 
l) CO-OP QUAIL STARTER MEDICATED, Net Wt. 50 Lbs, Recall # V-111-6; 
m) CO-OP QUAIL GROWER MEDICATED, 50 Lbs, Recall # V-112-6 
CODE 
Product manufactured from 02/01/2005 until 06/06/2006 
RECALLING FIRM/MANUFACTURER 
Alabama Farmers Cooperative, Inc., Decatur, AL, by telephone, fax, email 
and visit on June 9, 2006. FDA initiated recall is complete. 
REASON 
Animal and fish feeds which were possibly contaminated with ruminant based 
protein not labeled as "Do not feed to ruminants". 
VOLUME OF PRODUCT IN COMMERCE 
125 tons 
DISTRIBUTION 
AL and FL 
END OF ENFORCEMENT REPORT FOR AUGUST 2, 2006 
### 
10,000,000 lbs banned blood laced meat and bone meal mbm 2007
pens, PENS, PENS ??? 
*** Spraker suggested an interesting explanation for the occurrence of CWD. 
The deer pens at the Foot Hills Campus were built some 30-40 years ago by a Dr. 
Bob Davis. At or abut that time, allegedly, some scrapie work was conducted at 
this site. When deer were introduced to the pens they occupied ground that had 
previously been occupied by sheep. 
now, decades later ; 
2012 
PO-039: A comparison of scrapie and chronic wasting disease in white-tailed 
deer 
Justin Greenlee, Jodi Smith, Eric Nicholson US Dept. Agriculture; 
Agricultural Research Service, National Animal Disease Center; Ames, IA USA 
Interspecies transmission studies afford the opportunity to better 
understand the potential host range and origins of prion diseases. The purpose 
of these experiments was to determine susceptibility of white-tailed deer (WTD) 
to scrapie and to compare the resultant clinical signs, lesions, and molecular 
profiles of PrPSc to those of chronic wasting disease (CWD). We inoculated WTD 
intracranially (IC; n = 5) and by a natural route of exposure (concurrent oral 
and intranasal (IN); n = 5) with a US scrapie isolate. All deer were inoculated 
with a 10% (wt/vol) brain homogenate from sheep with scrapie (1ml IC, 1 ml IN, 
30 ml oral). All deer inoculated by the intracranial route had evidence of PrPSc 
accumulation. PrPSc was detected in lymphoid tissues as early as 7 
months-post-inoculation (PI) and a single deer that was necropsied at 15.6 
months had widespread distribution of PrPSc highlighting that PrPSc is widely 
distributed in the CNS and lymphoid tissues prior to the onset of clinical 
signs. IC inoculated deer necropsied after 20 months PI (3/5) had clinical 
signs, spongiform encephalopathy, and widespread distribution of PrPSc in neural 
and lymphoid tissues. The results of this study suggest that there are many 
similarities in the manifestation of CWD and scrapie in WTD after IC inoculation 
including early and widespread presence of PrPSc in lymphoid tissues, clinical 
signs of depression and weight loss progressing to wasting, and an incubation 
time of 21-23 months. Moreover, western blots (WB) done on brain material from 
the obex region have a molecular profile similar to CWD and distinct from 
tissues of the cerebrum or the scrapie inoculum. However, results of microscopic 
and IHC examination indicate that there are differences between the lesions 
expected in CWD and those that occur in deer with scrapie: amyloid plaques were 
not noted in any sections of brain examined from these deer and the pattern of 
immunoreactivity by IHC was diffuse rather than plaque-like. After a natural 
route of exposure, 100% of WTD were susceptible to scrapie. Deer developed 
clinical signs of wasting and mental depression and were necropsied from 28 to 
33 months PI. Tissues from these deer were positive for PrPSc by IHC and WB. 
Similar to IC inoculated deer, samples from these deer exhibited two different 
molecular profiles: samples from obex resembled CWD whereas those from cerebrum 
were similar to the original scrapie inoculum. On further examination by WB 
using a panel of antibodies, the tissues from deer with scrapie exhibit 
properties differing from tissues either from sheep with scrapie or WTD with 
CWD. Samples from WTD with CWD or sheep with scrapie are strongly immunoreactive 
when probed with mAb P4, however, samples from WTD with scrapie are only weakly 
immunoreactive. In contrast, when probed with mAb’s 6H4 or SAF 84, samples from 
sheep with scrapie and WTD with CWD are weakly immunoreactive and samples from 
WTD with scrapie are strongly positive. This work demonstrates that WTD are 
highly susceptible to sheep scrapie, but on first passage, scrapie in WTD is 
differentiable from CWD. 
2011 
*** After a natural route of exposure, 100% of white-tailed deer were 
susceptible to scrapie. 
Scrapie in Deer: Comparisons and Contrasts to Chronic Wasting Disease (CWD) 
Justin J. Greenlee of the Virus and Prion Diseases Research Unit, National 
Animal Disease Center, ARS, USDA, Ames, IA provided a presentation on scrapie 
and CWD in inoculated deer. Interspecies transmission studies afford the 
opportunity to better understand the potential host range and origins of prion 
diseases. We inoculated white-tailed deer intracranially (IC) and by a natural 
route of exposure (concurrent oral and intranasal inoculation) with a US scrapie 
isolate. All deer inoculated by the intracranial route had evidence of PrPSc 
accumulation and those necropsied after 20 months post-inoculation (PI) (3/5) 
had clinical signs, spongiform encephalopathy, and widespread distribution of 
PrPSc in neural and lymphoid tissues. A single deer that was necropsied at 15.6 
months PI did not have clinical signs, but had widespread distribution of PrPSc. 
This highlights the facts that 1) prior to the onset of clinical signs PrPSc is 
widely distributed in the CNS and lymphoid tissues and 2) currently used 
diagnostic methods are sufficient to detect PrPSc prior to the onset of clinical 
signs. The results of this study suggest that there are many similarities in the 
manifestation of CWD and scrapie in white-tailed deer after IC inoculation 
including early and widespread presence of PrPSc in lymphoid tissues, clinical 
signs of depression and weight loss progressing to wasting, and an incubation 
time of 21-23 months. Moreover, western blots (WB) done on brain material from 
the obex region have a molecular profile consistent with CWD and distinct from 
tissues of the cerebrum or the scrapie inoculum. However, results of microscopic 
and IHC examination indicate that there are differences between the lesions 
expected in CWD and those that occur in deer with scrapie: amyloid plaques were 
not noted in any sections of brain examined from these deer and the pattern of 
immunoreactivity by IHC was diffuse rather than plaque-like. After a natural 
route of exposure, 100% of white-tailed deer were susceptible to scrapie. Deer 
developed clinical signs of wasting and mental depression and were necropsied 
from 28 to 33 months PI. Tissues from these deer were positive for scrapie by 
IHC and WB. Tissues with PrPSc immunoreactivity included brain, tonsil, 
retropharyngeal and mesenteric lymph nodes, hemal node, Peyer’s patches, and 
spleen. While two WB patterns have been detected in brain regions of deer 
inoculated by the natural route, unlike the IC inoculated deer, the pattern 
similar to the scrapie inoculum predominates. 
Committee Business:
The Committee discussed and approved three resolutions regarding CWD. They 
can be found in the report of the Reswolutions Committee. Essentially the 
resolutions urged USDA-APHIS-VS to:
Continue to provide funding for CWD testing of captive cervids 
Finalize and publish the national CWD rule for Herd Certification and 
Interstate Movement 
Evaluate live animal test, including rectal mucosal biopsy, for CWD in 
cervids 
2011 Annual Report 
Research Project: TRANSMISSION, DIFFERENTIATION, AND PATHOBIOLOGY OF 
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES Location: Virus and Prion Research 
Unit 
2011 Annual Report 
In Objective 1, Assess cross-species transmissibility of transmissible 
spongiform encephalopathies (TSEs) in livestock and wildlife, numerous 
experiments assessing the susceptibility of various TSEs in different host 
species were conducted. Most notable is deer inoculated with scrapie, which 
exhibits similarities to chronic wasting disease (CWD) in deer suggestive of 
sheep scrapie as an origin of CWD. 
snip... 
4.Accomplishments 1. Deer inoculated with domestic isolates of sheep 
scrapie. Scrapie-affected deer exhibit 2 different patterns of disease 
associated prion protein. In some regions of the brain the pattern is much like 
that observed for scrapie, while in others it is more like chronic wasting 
disease (CWD), the transmissible spongiform encephalopathy typically associated 
with deer. This work conducted by ARS scientists at the National Animal Disease 
Center, Ames, IA suggests that an interspecies transmission of sheep scrapie to 
deer may have been the origin of CWD. This is important for husbandry practices 
with both captive deer, elk and sheep for farmers and ranchers attempting to 
keep their herds and flocks free of CWD and scrapie. 
White-tailed Deer are Susceptible to Scrapie by Natural Route of Infection 
Jodi D. Smith, Justin J. Greenlee, and Robert A. Kunkle; Virus and Prion 
Research Unit, National Animal Disease Center, USDA-ARS 
Interspecies transmission studies afford the opportunity to better 
understand the potential host range and origins of prion diseases. Previous 
experiments demonstrated that white-tailed deer are susceptible to sheep-derived 
scrapie by intracranial inoculation. The purpose of this study was to determine 
susceptibility of white-tailed deer to scrapie after a natural route of 
exposure. Deer (n=5) were inoculated by concurrent oral (30 ml) and intranasal 
(1 ml) instillation of a 10% (wt/vol) brain homogenate derived from a sheep 
clinically affected with scrapie. Non-inoculated deer were maintained as 
negative controls. All deer were observed daily for clinical signs. Deer were 
euthanized and necropsied when neurologic disease was evident, and tissues were 
examined for abnormal prion protein (PrPSc) by immunohistochemistry (IHC) and 
western blot (WB). One animal was euthanized 15 months post-inoculation (MPI) 
due to an injury. At that time, examination of obex and lymphoid tissues by IHC 
was positive, but WB of obex and colliculus were negative. Remaining deer 
developed clinical signs of wasting and mental depression and were necropsied 
from 28 to 33 MPI. Tissues from these deer were positive for scrapie by IHC and 
WB. Tissues with PrPSc immunoreactivity included brain, tonsil, retropharyngeal 
and mesenteric lymph nodes, hemal node, Peyer’s patches, and spleen. This work 
demonstrates for the first time that white-tailed deer are susceptible to sheep 
scrapie by potential natural routes of inoculation. In-depth analysis of tissues 
will be done to determine similarities between scrapie in deer after 
intracranial and oral/intranasal inoculation and chronic wasting disease 
resulting from similar routes of inoculation. 
see full text ; 
how many states have $465,000., and can quarantine and purchase there from, 
each cwd said infected farm, but how many states can afford this for all the cwd 
infected cervid game ranch type farms ??? 
? game farms in a state X $465,000., do all these game farms have insurance 
to pay for this risk of infected the wild cervid herds, in each state ??? 
how many game farms, are too many game farms ? 
when you have states handing out shooting pen permits like candy on 
halloween, just to advance their coffers, then other states wanting to do the 
same thing, with most all of them ignoring the science on shooting pens and cwd, 
what do you expect is going to happen. 
when is enough, enough ? 
Tuesday, December 20, 2011 
CHRONIC WASTING DISEASE CWD WISCONSIN Almond Deer (Buckhorn Flats) Farm 
Update DECEMBER 2011 
The CWD infection rate was nearly 80%, the highest ever in a North American 
captive herd. 
RECOMMENDATION: That the Board approve the purchase of 80 acres of land for 
$465,000 for the Statewide Wildlife Habitat Program in Portage County and 
approve the restrictions on public use of the site. 
Form 1100-001 
(R 2/11) 
NATURAL RESOURCES BOARD AGENDA ITEM 
SUBJECT: Information Item: Almond Deer Farm Update 
FOR: DECEMBER 2011 BOARD MEETING 
TUESDAY 
TO BE PRESENTED BY TITLE: Tami Ryan, Wildlife Health Section Chief 
SUMMARY: 
SEE MORE USAHA REPORTS HERE, 2012 NOT PUBLISHED YET...TSS 
Wednesday, November 14, 2012 
PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD INVESTIGATION MOVES INTO 
LOUISIANA and INDIANA 
Pennsylvania CWD number of deer exposed and farms there from much greater 
than first thought 
Published: Wednesday, October 17, 2012, 10:44 PM Updated: Wednesday, 
October 17, 2012, 11:33 PM 
Tuesday, October 23, 2012 
PA Captive deer from CWD-positive farm roaming free 
HERE, we see why these shooting pen owners some much like the USDA 
oversight of these game farms ;
USDA TO PGC ONCE CAPTIVES ESCAPE "it‘s no longer its business.” 
problem solved $$$...TSS
Sunday, January 06, 2013 
USDA TO PGC ONCE CAPTIVES ESCAPE "it‘s no longer its business.” 
what happened to the PA deer from the CWD index heard that went to 
Louisiana ??? 
or Indiana ??? 
Saturday, July 07, 2012 
TEXAS Animal Health Commission Accepting Comments on Chronic Wasting 
Disease Rule Proposal 
Considering the seemingly high CWD prevalence rate in the Sacramento and 
Hueco Mountains of New Mexico, CWD may be well established in the population and 
in the environment in Texas at this time. 
Friday, October 12, 2012 
Texas Animal Health Commission (TAHC) is Now Accepting Comments on Rule 
Proposals for “Chronic Wasting Disease (CWD)” 
TO: comments@tahc.state.tx.us; Texas Animal Health Commission (TAHC) 
***
The potential impact of prion diseases on human health was greatly 
magnified by the recognition that interspecies transfer of BSE to humans by beef 
ingestion resulted in vCJD. While changes in animal feed constituents and 
slaughter practices appear to have curtailed vCJD, there is concern that CWD of 
free-ranging deer and elk in the U.S. might also cross the species barrier. 
Thus, consuming venison could be a source of human prion disease. Whether BSE 
and CWD represent interspecies scrapie transfer or are newly arisen prion 
diseases is unknown. Therefore, the possibility of transmission of prion disease 
through other food animals cannot be ruled out. There is evidence that vCJD can 
be transmitted through blood transfusion. There is likely a pool of unknown size 
of asymptomatic individuals infected with vCJD, and there may be asymptomatic 
individuals infected with the CWD equivalent. These circumstances represent a 
potential threat to blood, blood products, and plasma supplies. 
Friday, November 09, 2012 
*** Chronic Wasting Disease CWD in cervidae and transmission to other 
species 
Sunday, November 11, 2012 
*** Susceptibilities of Nonhuman Primates to Chronic Wasting Disease 
November 2012 
Friday, December 14, 2012 
Susceptibility Chronic Wasting Disease (CWD) in wild cervids to Humans 2005 
- December 14, 2012 
Tuesday, December 18, 2012 
A Growing Threat How deer breeding could put public trust wildlife at risk 
Tuesday, April 02, 2013 
Ind. panel votes to allow fenced deer preserves 'shooting pens' 
tss
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