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Wednesday, November 15, 2017

Michigan confirms 11 case of CWD TSE Prion

CWD Testing Status Update - As of November 15, 2017


Deer Tested for Chronic Wasting Disease Since Detection of First Positive Deer (May 2015)

 
Targeted DeerRoadkill Deer
or Found Dead
Disease Control and
Crop Damage Permits
Culled By
Wildlife Services
Hunter
Harvested Deer
TotalConfirmed
CWD-Positive Deer
DMU 333 (20-Township)772445110113435181101479
DMU 419 (5-County)803092075239529960
DMU 359 (9-Township)821019910777512990
DMU 354 (2-County)271340142233170
Montcalm County Core (9-Township)752402723082
Western UP (4-County)72041017016413920
Remainder of State3921172558196818130
Totals: 59833032843155099781827211


CWD-positive deer are reflected in the totals and include 5 hunter-harvested, 1 targeted deer, and 5 deer culled by Wildlife Services.


TUESDAY, OCTOBER 24, 2017 
Michigan Another Montcalm County deer suspected to have CWD major concern,” said Dr. Kelly Straka, DNR state wildlife veterinarian

Chronic wasting disease identified in two Mecosta County farmed deer Agency: Agriculture and Rural Development
For immediate release: January 20, 2017 Media contact: Jessy Sielski (MDARD), 517-284-5725 or Chad Stewart (DNR), 517-282-4810
LANSING – Chronic wasting disease was confirmed this week in two female deer from a Mecosta County deer farm. CWD is a fatal neurological disease that affects white-tailed deer, mule deer, elk and moose. This is the second time the disease has been found in a farmed deer facility in Michigan. In 2008, a white-tailed deer from a Kent County deer farm tested positive.
“Chronic wasting disease is a serious disease affecting both farmed and free-ranging deer,” said MDARD State Veterinarian James Averill, DVM. “We are following the state’s CWD response plan and taking the necessary steps to protect the health and well-being of all of Michigan’s deer populations.”
Samples from the two deer were submitted for testing as a part of MDARD’s mandatory CWD surveillance program. All farmed deer facilities licensed with the Michigan Department Natural Resources must participate in this program. 
“Any discovery of chronic wasting disease in free-ranging or farmed deer is disappointing,” said Chad Stewart, DNR deer and elk specialist. “It will take significant time and effort – through immediate, targeted surveillance and mandatory checks during the upcoming deer seasons – to understand the current situation. The Michigan DNR remains committed in our efforts to contain this disease and safeguard our valuable wildlife resource.” 
MDARD and DNR are implementing the Michigan Surveillance and Response Plan for Chronic Wasting Disease of Free-Ranging and Privately Owned Cervids, and are taking the following steps:
• Quarantine the affected farm. • Complete trace investigations to identify the potential sources of infection and possible areas of spread. • Work with the producer to depopulate the facility. • Test all deer from the affected herd for CWD. • Identify all other deer farms in a 15-mile radius, which will undergo a records audit, fence inspection and increased surveillance testing. • Conduct targeted surveillance testing on free-ranging white-tailed deer near the facility. • Have mandatory deer check for hunter-harvested deer in a nine-township area.
An informational meeting for deer farmers is scheduled for:
Wednesday, February 1, 2017, at 7 p.m. Big Rapids Holiday Inn 1005 Perry Avenue, Big Rapids, Michigan 49307
In May 2015, CWD was found in a free-ranging deer in Ingham County. Since then, the DNR has tested nearly 12,000 free-ranging deer for CWD; nine deer have tested positive in Ingham and Clinton counties. 
CWD is transmitted directly from one animal to another and indirectly through the environment. Infected animals may display abnormal behavior, progressive weight loss and physical debilitation. To date, there is no evidence that CWD presents any risk to humans or other animals outside the deer family, either through contact with an infected deer or from handling venison that came from a CWD-infected deer. However, as a precaution, the U.S. Centers for Disease Control and the World Health Organization recommend that infected animals not be consumed as food by either humans or domestic animals.
More information about CWD – including Michigan’s CWD surveillance and response plan – is available at www.michigan.gov/cwd.
###

MONDAY, OCTOBER 02, 2017
Michigan 3 ½-year-old female deer likely to be the 10th free-ranging deer Chronic Wasting Disease CWD TSE Prion

FRIDAY, SEPTEMBER 29, 2017
Michigan Mandatory Deer Check in DMUs 333 and 359 Due to chronic wasting disease (CWD)

THURSDAY, SEPTEMBER 14, 2017
Michigan Chronic Wasting Disease CWD TSE Prion Update and Reminder

*** The potential impact of prion diseases on human health was greatly magnified by the recognition that interspecies transfer of BSE to humans by beef ingestion resulted in vCJD. While changes in animal feed constituents and slaughter practices appear to have curtailed vCJD, there is concern that CWD of free-ranging deer and elk in the U.S. might also cross the species barrier. Thus, consuming venison could be a source of human prion disease. Whether BSE and CWD represent interspecies scrapie transfer or are newly arisen prion diseases is unknown. Therefore, the possibility of transmission of prion disease through other food animals cannot be ruled out. There is evidence that vCJD can be transmitted through blood transfusion. There is likely a pool of unknown size of asymptomatic individuals infected with vCJD, and there may be asymptomatic individuals infected with the CWD equivalent. These circumstances represent a potential threat to blood, blood products, and plasma supplies. 

MICHIGAN CWD ARCHIVE 

FRIDAY, JANUARY 20, 2017 
Michigan Chronic wasting disease identified in two Mecosta County farmed deer

Friday, January 13, 2017 
Michigan confirms 9th case of CWD and DNR receives 1 Million Dollars from state for research there for BRAVO! 

Tuesday, November 22, 2016 
Michigan Suspect CWD deer harvested in Eagle Township, Clinton County 

Tuesday, September 13, 2016 
Michigan Suspect deer for chronic wasting disease identified in Ingham County 

Tuesday, July 05, 2016 
Michigan DNR announces expansion of Chronic Wasting Disease Core Area and Management Zone 

Friday, March 18, 2016 
Michigan confirms additional CWD-positive free-ranging, white-tailed deer, bringing the total to seven 

Wednesday, December 30, 2015 
Michigan Deer suspected positive for CWD found in Watertown Township; Jan. 12 public meeting set 

Tuesday, December 01, 2015 
MICHIGAN 4TH WILD CHRONIC WASTING DISEASE CWD SUSPECT CONFIRMED 

Friday, November 13, 2015 
*** Michigan Suspected CWD found in DeWitt Township deer tests are indicating that the deer could be the fourth case 

Thursday, August 06, 2015 
Michigan DNR confirms third deer positive for CWD; hunter participation is critical this fall 

Friday, July 17, 2015 
Michigan confirms CWD in second free-ranging white-tailed deer 

Tuesday, May 26, 2015 
Michigan confirms state's first case of chronic wasting disease in free-ranging white-tailed deer 

Monday, August 25, 2008 
CWD FIRST DOCUMENTED IN MICHIGAN Michigan's First Case of Chronic Wasting Disease Detected at Kent County Deer Breeding Facility 
Contact: Bridget Patrick (MDA) or Mary Dettloff (DNR) 517-241-2669 or 517-335-3014 Agency: Natural Resources 
August 25, 2008 LANSING - The Michigan departments of Agriculture (MDA) and Natural Resources (DNR) today confirmed the state's first case of Chronic Wasting Disease (CWD) in a three-year old white-tailed deer from a privately owned cervid (POC) facility in Kent County. 

Wednesday, September 07, 2016 
Michigan Launches an investigation into the Detroit Medical Center dirty, broken and missing surgical instruments, what about the CJD TSE PRION iatrogenic threat past and present therefrom? 

MICHIGAN FDA PART 589 -- SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEED VIOLATIONS OFFICIAL ACTION INDICATED OAI UPDATE BREACH APRIL 4, 2017

Greetings FDA HHS et al Enforcement Reports,

i have followed the mad cow saga since December 14, 1997, when i lost my Mom to the hvCJD. without going into all that and what i have been doing since then to bring awareness, i am reaching out to you privately, because i do not want to have to wait another 10 years to finally get an answer via the FOIA on feed or the infamous mad sheep of mad river valley testing blunder. i'm getting old and probably will not be around in 10 years. but what i am look for, you might be able to help me out with, and i will keep the source 'in confidence'. what i am looking for is the full report and amount of product in commerce being recalled (if any). i am extremely concerned with the 21 CFR 589.2000 feed regulations and risk factors there from cervid, pigs, dogs, cats. we now have cwd transmitting to pigs orally in the lab, and this is getting serious now. i know OAI actions are severe from the past OAIs and investigations there from. but if you could please give me a full report of exactly what this OAI violation consisted of, or someone that can, without years of FOIA requests and denials and appeals, it would be most helpful, and very much appreciated. i am not the enemy, i have simply been trying to fix a wrong for almost 2 decades every day, but seems i have failed. i made a promise to mom, never forget, and never let them forget. i hope to hear back from you...

with kindest regards, terry 

11998 DET-DO MI 48846-847 OPR 4/4/2017 OAI 

Subject: MICHIGAN FDA PART 589 -- SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEED VIOLATIONS OFFICIAL ACTION INDICATED OAI UPDATE BREACH APRIL 4, 2017
MICHIGAN FDA PART 589 -- SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEEDVIOLATIONS OFFICIAL ACTION INDICATED OAI UPDATE BREACH APRIL 4, 2017
FDA BSE/Ruminant Feed Inspections Firms Inventory 
11998 DET-DO MI 48846-847 OPR 4/4/2017 OAI 

NAI = NO ACTION INDICATED
OAI = OFFICIAL ACTION INDICATED
VAI = VOLUNTARY ACTION INDICATED
RTS = REFERRED TO STATE
OAI (Official Action Indicated) when inspectors find significant objectionable conditions or practices and believe that regulatory sanctions are warranted to address the establishment’s lack of compliance with the regulation. An example of an OAI classification would be findings of manufacturing procedures insufficient to ensure that ruminant feed is not contaminated with prohibited material. Inspectors will promptly re-inspect facilities classified OAI after regulatory sanctions have been applied to determine whether the corrective actions are adequate to address the objectionable conditions. 

2012-2013
Product Details
Product Description: Regular Chicken 50# 
Ingredients: Corn, Wheat, Oats, Oyster shells, Medium Grit, CCC, ADS, Plant Protein Products, Animal Protein Products, Processed Grain By-Products, Roughage Products, Animal Fat procession with DHA, etc 
Reason for Recall: During an FDA sample collection, the firms 50# Regular Chicken Feed was found to contain mammalian protein. The label does not contain the warning statement. 
Product Quantity: 5400lbs (50lb bags) 
Recall Number: V-137-2013 Code Information: 8/6/2012 Classification: 
Class III Event Details
Event ID: 63743 
Voluntary / Mandated: 
Voluntary: 
Firm Initiated Product Type: 
Veterinary Initial Firm Notification of Consignee or Public: 
Other Status: Terminated 
Distribution Pattern: Midland MI area only. 
Recalling Firm: Cohoons Elevator Inc. 802 Townsend St Midland, MI 48640-5362 United States 
Recall Initiation Date: 11/21/2012 Center Classification Date: 2/8/2013 Date Terminated: 2/12/2013 

FRIDAY, NOVEMBER 3, 2017

BSE MAD COW TSE PRION DISEASE PET FOOD FEED IN COMMERCE INDUSTRY VS TERRY S. SINGELTARY Sr. A REVIEW

''I have a neighbor who is a dairy farmer. He tells me that he knows of several farmers who feed their cattle expired dog food. These farmers are unaware of any dangers posed to their cattle from the pet food contents. For these farmers, the pet food is just another source of protein.''

IN CONFIDENCE



SATURDAY, NOVEMBER 4, 2017 

FDA 589.2000, Section 21 C.F.R. Animal Proteins Prohibited in Ruminant Feed WARNING Letters and FEED MILL VIOLATIONS OBSERVATIONS 2017 to 2006



OFFICIAL REPORT U.K. GOVERNMENT DEFRA

What is the risk of chronic wasting disease being introduced into Great Britain? A Qualitative Risk Assessment October 2012

Several different animal feed products are imported into GB from North America. These include processed pet foods and consignments of unfinished feed ingredients for use in animal feed. The amount of imported feed, including pet food, that contains cervid protein is unknown and identified as a significant data gap. As non-ruminant animal feed may be produced with cervid protein (but not from positive CWD animals) in the United States (US), there is a greater than negligible risk that feed with cervid protein is imported from North America into GB. There is, however, uncertainty associated with this estimate.

snip...

In summary, given the volume of tourists, hunters and servicemen moving between GB and North America, the probability of at least one person travelling to/from a CWD affected area and, in doing so, contaminating their clothing, footwear and/or equipment prior to arriving in GB is greater than negligible. For deer hunters, specifically, the risk is likely to be greater given the increased contact with deer and their environment. However, there is significant uncertainty associated with these estimates.

snip...

Therefore, it is considered that farmed and park deer may have a higher probability of exposure to CWD transferred to the environment than wild deer given the restricted habitat range and higher frequency of contact with tourists and returning GB residents.

snip...

What is the risk of chronic wasting disease being introduced into Great Britain? A Qualitative Risk Assessment October 2012



Thursday, April 07, 2016

What is the risk of chronic wasting disease being introduced into Great Britain? An updated Qualitative Risk Assessment March 2016


*** PLEASE SEE THIS URGENT UPDATE ON CWD AND FEED ANIMAL PROTEIN ***

cwd to pig, orally ;

Research Project: TRANSMISSION, DIFFERENTIATION, AND PATHOBIOLOGY OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES

Location: Virus and Prion Research

Title: Disease-associated prion protein detected in lymphoid tissues from pigs challenged with the agent of chronic wasting disease

Author item Moore, Sarah item Kunkle, Robert item Kondru, Naveen item Manne, Sireesha item Smith, Jodi item Kanthasamy, Anumantha item West Greenlee, M item Greenlee, Justin

Submitted to: Prion Publication Type: Abstract Only Publication Acceptance Date: 3/15/2017 Publication Date: N/A Citation: N/A Interpretive Summary:

Technical Abstract: Aims: Chronic wasting disease (CWD) is a naturally-occurring, fatal neurodegenerative disease of cervids. We previously demonstrated that disease-associated prion protein (PrPSc) can be detected in the brain and retina from pigs challenged intracranially or orally with the CWD agent. In that study, neurological signs consistent with prion disease were observed only in one pig: an intracranially challenged pig that was euthanized at 64 months post-challenge. The purpose of this study was to use an antigen-capture immunoassay (EIA) and real-time quaking-induced conversion (QuIC) to determine whether PrPSc is present in lymphoid tissues from pigs challenged with the CWD agent.

Methods: At two months of age, crossbred pigs were challenged by the intracranial route (n=20), oral route (n=19), or were left unchallenged (n=9). At approximately 6 months of age, the time at which commercial pigs reach market weight, half of the pigs in each group were culled (<6 challenge="" groups="" month="" pigs="" remaining="" the="">6 month challenge groups) were allowed to incubate for up to 73 months post challenge (mpc). The retropharyngeal lymph node (RPLN) was screened for the presence of PrPSc by EIA and immunohistochemistry (IHC). The RPLN, palatine tonsil, and mesenteric lymph node (MLN) from 6-7 pigs per challenge group were also tested using EIA and QuIC.

Results: PrPSc was not detected by EIA and IHC in any RPLNs. All tonsils and MLNs were negative by IHC, though the MLN from one pig in the oral <6 5="" 6="" at="" by="" detected="" eia.="" examined="" group="" in="" intracranial="" least="" lymphoid="" month="" months="" of="" one="" pigs="" positive="" prpsc="" quic="" the="" tissues="" was="">6 months group, 5/6 pigs in the oral <6 4="" and="" group="" months="" oral="">6 months group. Overall, the MLN was positive in 14/19 (74%) of samples examined, the RPLN in 8/18 (44%), and the tonsil in 10/25 (40%). Conclusions:

This study demonstrates that PrPSc accumulates in lymphoid tissues from pigs challenged intracranially or orally with the CWD agent, and can be detected as early as 4 months after challenge.

CWD-infected pigs rarely develop clinical disease and if they do, they do so after a long incubation period. This raises the possibility that CWD-infected pigs could shed prions into their environment long before they develop clinical disease.

Furthermore, lymphoid tissues from CWD-infected pigs could present a potential source of CWD infectivity in the animal and human food chains.


CONFIDENTIAL

EXPERIMENTAL PORCINE SPONGIFORM ENCEPHALOPATHY

While this clearly is a cause for concern we should not jump to the conclusion that this means that pigs will necessarily be infected by bone and meat meal fed by the oral route as is the case with cattle. ...


we cannot rule out the possibility that unrecognised subclinical spongiform encephalopathy could be present in British pigs though there is no evidence for this: only with parenteral/implantable pharmaceuticals/devices is the theoretical risk to humans of sufficient concern to consider any action.


 Our records show that while some use is made of porcine materials in medicinal products, the only products which would appear to be in a hypothetically ''higher risk'' area are the adrenocorticotrophic hormone for which the source material comes from outside the United Kingdom, namely America China Sweden France and Germany. The products are manufactured by Ferring and Armour. A further product, ''Zenoderm Corium implant'' manufactured by Ethicon, makes use of porcine skin - which is not considered to be a ''high risk'' tissue, but one of its uses is described in the data sheet as ''in dural replacement''. This product is sourced from the United Kingdom.....


 snip...see much more here ;

WEDNESDAY, APRIL 05, 2017

Disease-associated prion protein detected in lymphoid tissues from pigs challenged with the agent of chronic wasting disease


MONDAY, AUGUST 14, 2017 

Experimental transmission of the chronic wasting disease agent to swine after oral or intracranial inoculation



TUESDAY, APRIL 18, 2017 

EXTREME USA FDA PART 589 TSE PRION FEED LOOP HOLE STILL EXIST, AND PRICE OF POKER GOES UP



see massive amounts of suspect banned mad cow protein in commerce of the past 2 decades, since the Aug., 4, 1997 ban...



Terry S. Singeltary Sr.

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