Chronic Wasting Disease CWD TSE Prion Surveillance and Testing in Texas, a very concerning situation
Chronic Wasting Disease CWD TSE Prion Surveillance and Testing in Texas, a
concerning situation...TSS
Dear Deer Breeder,
In March I received a call from a worried deer breeder who is also a great
friend. He had a lot of deer that had come from a positive facility and was in a
trace out and hold order. He knew it would all be ok because he owned the deer
longer than 18 months which would allow the live tonsil test to be used to free
his herd. There was a problem though. He had recently sold five of them and they
had been released on a hunting facility. He indicated that they were not his
best does and he thought they could easily harvest all of them. As sad as it
was, the best advice I had was to instruct him to do just that. He also lined up
a Vet to perform the live animal Palatine Tonsil test on the remainder of those
deer on his farm and other farms that he had sold some great animals to, which
had all come from the positive facility.
After a few days and numerous calls with TAHC and TPWD we, myself and the
breeder, received permission to allow the harvest of the five animals. He had
harvested three of the five but couldn't find the last two. He asked if I could
help him get permission to fly the ranch with a helicopter to find the remaining
animals. Many calls and texts happened over the next couple of hours and then
they were airborne. They got number four and finally located the last doe. The
problem was that she had been dead for close to a month. He text me a picture
and said he had found her but it was too late. I immediately called while he was
still at the ranch. I asked him to remove the head, drive to his Vet and call me
from the Vet's office. An hour later he called and I got the Vet on the phone.
This was on a Friday so I asked the Vet to place the head in a bucket and
completely submerse it in formalin, drill a couple of tap holes in the top of
the skull plate and let it set for the weekend and we would take care of the
rest on Monday.
Monday, the DBC was holding our first rectal training class at Texas Tech.
It started early, and during a break the breeder called and said the Vet had
sent the head to TVMDL. I asked if the whole head was sent while still in
formalin and found out that it was never put in formalin. I told the breeder I
would try to get it fixed. After the class, I reached TVMDL and said a bad head
was sent and needed to know what had happened to it. I was told that it had been
thrown out. I was sitting with a researcher that knows more about CWD than
anyone I have met. It was his necropsy that was read as the first positive in
1967. We talked and I picked his brain until late into the night about CWD. This
knowledge would prove invaluable over the next few days. The next day I drove
him to the airport and while I was leaving, the breeder called and said the head
had mysteriously been found. I asked to have the Vet get it back ASAP. He said
it couldn't be sent back because it had been in the laboratory. I sent him a
text with instructions on where to have it overnighted. After a bit he called
back totally distraught saying that they actually didn't have it. I have no clue
what the rest of the story is and I can't relay what our conversation consisted
of at this point.
I asked if he could get the rest of the body of the deer. He called back
and said it had been buried. I told him to get a shovel and a large cooler and
drive to the ranch to dig it up. He arrived at the ranch and began looking for
the spot where it was buried. He had left with the head several days prior
before the body was buried and didn't know where it was placed. He was walking
around jumping up and down on the ground to find a soft spot. He finally felt a
spot that he thought was soft. He and his brother began to dig and sure enough
they had found it. The stench and maggot infested carcass had his brother
throwing up. I instructed him to place the complete spine in the cooler and
overnight it to Colorado State. He did so and I was informed by Colorado State
when it arrived. I don't want to go into the calamity that transpired in
shipping. It was there in one long piece. A great report came in that evening
when I was called and told there was still viable spinal cord tissue that could
be tested. A couple of days later, we received the great news. A negative Eliza
and IHC test on the spinal tissue had been achieved. The deer had been on his
farm long enough that the tissue would have been positive if it had CWD. All of
the tonsil tests were taken and received back negative. 100% good samples and
100% negative. He was released!!!! We got very lucky even though the
circumstances were stacked against us. The breeder is responsible for his own
release because the agencies could see his good faith effort to do all he could.
He immediately started on the problem, did everything he could and was lucky
that we had the right guy in town at the right time. There were many people that
made this happen. Dr. Terry Spraker (who was also able to test the skull from
Tuesdays eblast) from Colorado State, Randy Rainer and many from the TAHC and
TPWD staff as well as Dr. Randy Froehlich DVM. The breeders in these stories can
make their names public if they would like.
Thanks,
Tim Condict
‘’The problem was that she had been dead for close to a month’’
‘’I asked if the whole head was sent while still in formalin and found out
that it was never put in formalin. I told the breeder I would try to get it
fixed. After the class, I reached TVMDL and said a bad head was sent and needed
to know what had happened to it. I was told that it had been thrown out’’.
‘’The next day I drove him to the airport and while I was leaving, the
breeder called and said the head had mysteriously been found. I asked to have
the Vet get it back ASAP. He said it couldn't be sent back because it had been
in the laboratory. I sent him a text with instructions on where to have it
overnighted. After a bit he called back totally distraught saying that they
actually didn't have it. I have no clue what the rest of the story is and I
can't relay what our conversation consisted of at this point.’’
‘’I asked if he could get the rest of the body of the deer. He called back
and said it had been buried. I told him to get a shovel and a large cooler and
drive to the ranch to dig it up. He arrived at the ranch and began looking for
the spot where it was buried. He had left with the head several days prior
before the body was buried and didn't know where it was placed. He was walking
around jumping up and down on the ground to find a soft spot. He finally felt a
spot that he thought was soft. He and his brother began to dig and sure enough
they had found it. The stench and maggot infested carcass had his brother
throwing up. I instructed him to place the complete spine in the cooler and
overnight it to Colorado State. He did so and I was informed by Colorado State
when it arrived.’’
‘’A negative Eliza and IHC test on the spinal tissue had been achieved.
The deer had been on his farm long enough that the tissue would have been
positive if it had CWD. All of the tonsil tests were taken and received back
negative. 100% good samples and 100% negative. He was released!!!! ‘’
LMAO!
and this is what testing for cwd bse scrapie tse prion in Texas looks like
nothing like CWD testing in Texas.
reminds me of the infamous mad cow cover up, where a positive sample sat up
on a shelf for 7 months classified as negative, where it finally took an act of
Congress to confirm BSE.
this CWD surveillance and testing program in Texas is as big a joke as the
mad cow testing. they may as well call it what kline calls it, shoot, shovel,
and shut the hell up, the SSS TSE Prion surveillance and testing program.
GOOD OLD BOY TSE PRION SURVEILLANCE AND TESTING IS ALIVE AND WELL IN TEXAS,
and the call it the shoot, shovel, and shut up SSS policy. it has worked very
well for TAHC and TPWD et al.
Chronic Wasting Disease Wednesday, July 22, 2015 Texas Certified Chronic
Wasting Disease CWD Sample Collector, like the Wolf Guarding the Henhouse Just
got off the phone with TAHC, and I wanted to confirm this. but it seems true,
that in the state of Texas, even if you are a Captive game farmer, breeder, part
of the captive industry at all, if you want to sample your own cervid for cwd,
instead of the TAHC, TPWD, or Doctor, all you have to do is pass the Certified
CWD Sample Collector course, and bingo, you sample your own herd. ...tss
Saturday, May 28, 2016
TPWD gives in to Breeders again and postponed their decision regarding
proposed changes to state regulations for managing CWD allowing the TSE Prion to
spread further
Sunday, May 22, 2016
TEXAS CWD DEER BREEDERS PLEA TO GOVERNOR ABBOTT TO CIRCUMVENT TPWD SOUND
SCIENCE TO LET DISEASE SPREAD
Wednesday, May 04, 2016
TPWD proposes the repeal of §§65.90 -65.94 and new §§65.90 -65.99
Concerning Chronic Wasting Disease - Movement of Deer Singeltary Comment
Submission
Friday, April 22, 2016
Texas Scrapie Confirmed in a Hartley County Sheep where CWD was detected in
a Mule Deer
Saturday, April 02, 2016
TEXAS TAHC BREAKS IT'S SILENCE WITH TWO MORE CASES CWD CAPTIVE DEER
BRINGING TOTAL TO 10 CAPTIVES REPORTED TO DATE
Friday, February 26, 2016
TEXAS Hartley County Mule Deer Tests Positive for Chronic Wasting Disease
CWD TSE Prion
Friday, February 05, 2016
TEXAS NEW CHRONIC WASTING DISEASE CWD CASE DISCOVERD AT CAPTIVE DEER
RELEASE SITE
Sunday, January 17, 2016
Texas 10,000 deer in Texas tested for deadly disease CWD TSE, but not
tested much in the most logical place, the five-mile radius around the Medina
County captive-deer facility where it was discovered
Friday, January 15, 2016
TEXAS PARKS & WILDLIFE CWD Ante-Mortem Testing Symposium Texas Disposal
Systems Events Pavilion January 12, 2016
Tuesday, December 29, 2015
TEXAS MONTHLY CHRONIC WASTING DISEASE CWD JANUARY 2016 DEER BREEDERS STILL
DON'T GET IT $
Chronic Wasting Unease
The emergence of a deadly disease has wildlife officials and deer breeders
eyeing each other suspiciously.
Monday, November 16, 2015
TEXAS PARKS AND WILDLIFE DEPARTMENT EXECUTIVE DIRECTOR ORDER NO. 015-006
Chronic Wasting Disease (CWD) immediate danger to the white-tailed deer and mule
deer resources of Texas
Saturday, November 14, 2015
TEXAS CAPTIVE BREEDER CHRONIC WASTING DISEASE CWD 2 MORE SUSPECTS DECTECTED
BRINGING NUMBER TO 7 DETECTED IN CAPTIVE BREEDER (if/when the last two are
confirmed).
Thursday, November 05, 2015
*** TPW Commission Adopts Interim Deer Breeder Movement Rules
Thursday, September 24, 2015
TEXAS Hunters Asked to Submit Samples for Chronic Wasting Disease CWD TSE
Prion Testing
*** I cannot stress enough to all of you, for the sake of your family and
mine, before putting anything in the freezer, have those deer tested for CWD.
...terry
Sunday, September 13, 2015
TEXAS DETECTS MORE DEER POSITIVE FOR CHRONIC WASTING DISEASE CWD tested at
a Tier 1 facility (a facility that either sold to or purchased directly from the
index facility)
Friday, October 09, 2015
Texas TWA Chronic Wasting Disease TSE Prion Webinars and Meeting October
2015
Tuesday, October 06, 2015
TAHC 393rd Commission Meeting Chronic Wasting Disease CWD TSE Prion October
6, 2015
Saturday, October 03, 2015
TEXAS CHRONIC WASTING DISEASE CWD TSE PRION GOD MUST NOT BE A TEXAN 2002 TO
2015
Wednesday, March 25, 2015
*** Chronic Wasting Disease CWD Cases Confirmed In New Mexico 2013 and 2014
UPDATE 2015
Wednesday, March 18, 2015
Chronic Wasting Disease CWD Confirmed Texas Trans Pecos March 18,
2015
TEXAS DEER CZAR SENT TO WISCONSIN TO SOLVE CWD CRISIS, WHILE ROME (TEXAS)
BURNS
Tuesday, August 11, 2015
Wisconsin doing what it does best, procrastinating about CWD yet again
thanks to Governor Walker
TEXAS DEER CZAR SENT TO WISCONSIN TO SOLVE CWD CRISIS, WHILE ROME (TEXAS)
BURNS
Wednesday, March 04, 2015
*** Disease sampling results provide current snapshot of CWD in Wisconsin
finding 324 positive detections statewide in 2014
Friday, June 01, 2012
*** TEXAS DEER CZAR TO WISCONSIN ASK TO EXPLAIN COMMENTS
RAW, UNCUT, AND UNCENSORED
Sunday, August 23, 2015
TAHC Chronic Wasting Disease CWD TSE Prion and how to put lipstick on a pig
and take her to the dance in Texas
Friday, August 07, 2015
*** Texas CWD Captive, and then there were 4 ?
Thursday, August 06, 2015
*** WE HAVE LOST TEXAS TO CWD TASK FORCE CATERING TO INDUSTRY
Tuesday, July 21, 2015
*** Texas CWD Medina County Herd Investigation Update July 16, 2015 ***
Thursday, July 09, 2015
TEXAS Chronic Wasting Disease (CWD) Herd Plan for Trace-Forward Exposed
Herd with Testing of Exposed Animals
Wednesday, July 01, 2015
*** TEXAS Chronic Wasting Disease Detected in Medina County Captive Deer
Tuesday, December 16, 2014
Texas 84th Legislature 2015 H.R. No. 2597 Kuempel Deer Breeding Industry
TAHC TPWD CWD TSE PRION
Thursday, May 02, 2013
*** Chronic Wasting Disease (CWD) Texas Important Update on OBEX ONLY
TEXTING
Monday, February 11, 2013
TEXAS CHRONIC WASTING DISEASE CWD Four New Positives Found in Trans Pecos
Tuesday, July 10, 2012
Chronic Wasting Disease Detected in Far West Texas
Monday, March 26, 2012
Texas Prepares for Chronic Wasting Disease CWD Possibility in Far West
Texas
***for anyone interested, here is some history of CWD along the Texas, New
Mexico border, and my attempt to keep up with it...terry
***CWD TEXAS TAHC OLD FILE HISTORY
updated from some of my old files. ...
Subject: CWD SURVEILLANCE STATISTICS TEXAS (total testing figures less than
50 in two years)
Date: Sun, 25 Aug 2002 21:06:49 –0700
From: "Terry S. Singeltary Sr."
Reply-To: Bovine Spongiform Encephalopathy
To: BSE-L@uni-karlsruhe.de
######## Bovine Spongiform Encephalopathy #########
greetings list members,
here are some figures on CWD testing in TEXAS...TSS
Dear Dr. Singletary,
In Fiscal Year 2001, seven deer from Texas were tested by the National
Veterinary Services Laboratory (NVSL) for CWD (5 fallow deer and 2 white-tailed
deer). In Fiscal Year 2002, seven elk from Texas were tested at NVSL (no deer).
During these two years, an additional six elk and one white-tailed deer were
tested at the Texas Veterinary Medical Diagnostic Laboratory (TVMDL). In Fiscal
Year 2002, four white-tailed deer (free-ranging clinical suspects) and at least
eight other white-tailed deer have been tested at TVMDL. One elk has been tested
at NVSL. All of these animals have been found negative for CWD. Dr. Jerry Cooke
of the Texas Parks and Wildlife Department also has records of 601 clinically
ill white-tailed deer which were necropsied at Texas A&M during the late
1960's and early 1970's, and no spongiform encepalopathies were noted. Thank you
for your consideration.
xxxxxxx
Texas Animal Health Commission
(personal communication...TSS)
Austin 8 news
snip...
"There's about 4 million deer in the state of Texas, and as a resource I
think we need to be doing as much as we can to look for these diseases," said
Doug Humphreys with Texas Parks and Wildlife. "Right now Texas is clear. We
haven't found any, but that doesn't mean we don't look."
With approximately 4 million animals, Texas has the largest population of
white-tailed deer in the nation. In addition, about 19,000 white-tailed deer and
17,000 elk are being held in private facilities. To know if CWD is present in
captive herds, TPWD and Texas Animal Health Commission are working with breeders
to monitor their herds.
How is it spread?
It is not known exactly how CWD is spread. It is believed that the agent
responsible for the disease may be spread both directly (animal to animal
contact) and indirectly (soil or other surface to animal). It is thought that
the most common mode of transmission from an infected animal is via saliva,
feces, and urine.
some surveillance?
beyond the _potential_ methods of transmissions above, why, not a single
word of SRM of various TSE species in feed as a source?
it's a known fact they have been feeding the deer/elk the same stuff as
cows here in USA.
and the oral route has been documented of CWD to mule deer fawns in lab
studies.
not to say that other _potential_ transmission mechanisms are possible, but
why over look the obvious?
TSS
########### http://mailhost.rz.uni-karlsruhe.de/warc/bse-l.html
############
From: Ken Waldrup, DVM, PhD (host25-207.tahc.state.tx.us)
Subject: Re: CWD SAMPLING TEXAS (but NOT in the obvious place, the NM,
TEXAS border)
Date: December 15, 2003 at 3:43 pm PST
In Reply to: CWD SAMPLING TEXAS (but NOT in the obvious place, the NM,
TEXAS border) posted by TSS on December 12, 2003 at 2:15 pm:
Dear sirs:
With regard to your comment about Texas NOT looking for CWD along the New
Mexico border, it is painfully obvious that you do not know or understand the
natural distribution of mule deer out there or the rights of the land owners in
this state. As of 15 December 2003, a total of 42 deer had been sampled from
what we call "Trans-Pecos", beyond the Pecos River. Mule deer are very widely
dispersed through this area, sometimes at densities of one animal per 6 square
miles. The Texas Parks and Wildlife Department does not have the legal authority
to trepass on private property to collect deer. Some landowners are cooperative.
Some are not. Franklin State Park is at the very tip of Texas, and deer from the
park have been tested (all negative). One of the single largest land owners
along the border is the National Park Service. Deer and elk from the Guadalupe
Peak National Park cannot be collected with federal permission. The sampling
throughout the state is based on the deer populations by eco-region and is
dictated by the availability of funds. I am concerned about your insinuation
that CWD is a human health risk. We are at a stand-off - you have no proof that
it is and I have no definitive proof that it isn't. However I would say that the
inferred evidence from Colorado, Wyoming and Wisconsin suggests that CWD is not
a human health concern (i.e. no evidence of an increased incidence of human
brain disorders within the CWD "endemic" areas of these states). From my
professional interactions with the Texas Parks and Wildlife Department, I can
definitely say that they want to do a thorough and sound survey throughout the
state, not willy-nilly "look here, look there". There are limitations of
manpower, finances and, in some places, deer populations. I would congratulate
TPWD for doing the best job with the limitations at hand rather than trying to
browbeat them when you obviously do not understand the ecology of West Texas.
Thank you for your consideration.
======================
From: TSS (216-119-139-126.ipset19.wt.net)
Subject: Re: CWD SAMPLING TEXAS (but NOT in the obvious place, the NM,
TEXAS border)
Date: December 16, 2003 at 11:03 am PST
In Reply to: Re: CWD SAMPLING TEXAS (but NOT in the obvious place, the NM,
TEXAS border) posted by Ken Waldrup, DVM, PhD on December 15, 2003 at 3:43 pm:
HEllo Dr. Waldrup,
thank you for your comments and time to come to this board.
Ken Waldrup, DVM, PhD states;
> it is painfully obvious that you do not know or understand the natural
distribution of mule deer out there or the rights of the land owners in this
state...
TSS states;
I am concerned about all deer/elk not just mule deer, and the rights of
land owners (in the case with human/animal TSEs) well i am not sure of the
correct terminology, but when the States deer/elk/cattle/sheep/humans are at
risk, there should be no rights for land owners in this case. the state should
have the right to test those animals. there are too many folks out there that
are just plain ignorant about this agent. with an agent such as this, you cannot
let landowners (and i am one) dictate human/animal health, especially when you
cannot regulate the movement of such animals...
Ken Waldrup, DVM, PhD states;
> Deer and elk from the Guadalupe Peak National Park cannot be collected
with federal permission.
TSS states;
I do not understand this? so there is no recourse of action even if every
deer/elk was contaminated with CWD in this area (hypothetical)?
Ken Waldrup, DVM, PhD states;
> I am concerned about your insinuation that CWD is a human health risk.
We are at a stand-off - you have no proof that it is and I have no definitive
proof that it isn't. However I would say that the inferred evidence from
Colorado, Wyoming and Wisconsin suggests that CWD is not a human health concern
(i.e. no evidence of an increased incidence of human brain disorders within the
CWD "endemic" areas of these states)...
TSS states;
NEXT, let's have a look at the overall distribution of CWD in Free-Ranging
Cervids and see where the CWD cluster in NM WSMR borders TEXAS;
Current Distribution of Chronic Wasting Disease in Free-Ranging Cervids
NOW, the MAP of the Exoregion where the samples were taken to test for CWD;
CWD SURVEILLANCE SAMPLE SUBMISSIONS TEXAS
Ecoregions of TEXAS
IF you look at the area around the NM WSMR where the CWD cluster was and
where it borders TEXAS, that ecoregion is called Trans Pecos region. Seems if my
Geography and my Ciphering is correct ;-) that region only tested 55% of it's
goal. THE most important area on the MAP and they only test some 96 samples,
this in an area that has found some 7 positive animals? NOW if we look at the
only other border where these deer from NM could cross the border into TEXAS,
this area is called the High Plains ecoregion, and again, we find that the
sampling for CWD was pathetic. HERE we find that only 9% of it's goal of CWD
sampling was met, only 16 samples were tested from some 175 that were suppose to
be sampled.
AS i said before;
> SADLY, they have not tested enough from the total population to
> know if CWD is in Texas or not.
BUT now, I will go one step further and state categorically that they are
not trying to find it. just the opposite it seems, they are waiting for CWD to
find them, as with BSE/TSE in cattle, and it will eventually...
snip...end...TSS
===============================
2005
SEE MAP OF CWD ON THE BORDER OF NEW MEXICO VERY CLOSE TO TEXAS ;
NO update on CWD testing in Texas, New Mexico that i could find. I have
inquired about it though, no reply yet...
-------- Original Message --------
Subject: CWD testing to date TEXAS ?
Date: Mon, 09 May 2005 12:26:20 –0500
From: "Terry S. Singeltary Sr."
To: kristen.everett@tpwd.state.tx.us
Hello Mrs. Everett,
I am most curious about the current status on CWD testing in Texas. could
you please tell me what the current and past testing figures are to date and
what geographical locations these tests have been in. good bust on the illegal
deer trapping case. keep up the good work there.........
thank you, with kindest regards,
Terry S. Singeltary Sr. P.O. Box 42 Bacliff, Texas USA 77518
-------- Original Message --------
Subject: CWD testing in New Mexico
Date: Mon, 09 May 2005 14:39:18 –0500
From: "Terry S. Singeltary Sr."
To: ispa@state.nm.us
Greetings,
I am most curious of the current and past CWD testing in New Mexico, and
there geographical locations...
thank you,
Terry S. Singeltary SR. CJD Watch
#################### https://lists.aegee.org/bse-l.html
####################
2006
----- Original Message -----
From: "Terry S. Singeltary Sr." flounder9@VERIZON.NET
To: BSE-L@aegee.org
Sent: Saturday, December 23, 2006 1:47 PM
Subject: CWD in New Mexico 35 MILES FROM TEXAS BORDER and low testing
sampling figures -- what gives TAHC ???
Subject: CWD in New Mexico 35 MILES FROM TEXAS BORDER and low testing
sampling figures -- what gives TAHC ???
Date: December 23, 2006 at 11:25 am PST
Greetings BSE-L members,
i never know if i am going crazy or just more of the same BSe. several
years ago i brought up the fact to the TAHC that CWD was literally at the Texas
borders and that the sample size for cwd testing was no where near enough in the
location of that zone bordering NM. well, i just wrote them another letter
questioning this again on Dec. 14, 2006 (see below) and showed them two
different pdf maps, one referencing this url, which both worked just fine then.
since then, i have NOT received a letter from them answering my question, and
the url for the map i used as reference is no longer working? i had reference
this map several times from the hunter-kill cwd sampling as of 31 August 2005
pdf which NO longer works now??? but here are those figures for that zone
bordering NM, for those that were questioning the url. the testing samples
elsewhere across Texas where much much more than that figure in the zone
bordering NM where CWD has been documented bordering TEXAS, near the White Sands
Missile Range. SO, why was the Texas hunter-kill cwd sampling as of 31 August
2005 document removed from the internet??? you know, this reminds me of the
infamous TEXAS MAD COW that i documented some 7 or 8 months before USDA et al
documented it, when the TAHC accidentally started ramping up for the
announcement on there web site, then removed it (see history at bottom). i am
not screaming conspiracy here, but confusious is confused again on the ciphering
there using for geographical distribution of cwd tissue sample size survey, IF
they are serious about finding CWD in TEXAS. common sense would tell you if cwd
is 35 miles from the border, you would not run across state and have your larger
samples there, and least samples 35 miles from where is what
found..........daaa..........TSS
THEN NOTICE CWD sample along that border in TEXAS, Three Year Summary of
Hunter-Kill CWD sampling as of 31 August 2005 of only 191 samples, then compare
to the other sample locations ;
TPWD has been conducting surveys of hunter-kill animals since 2002 and has
collected more than 7300 samples (as of 31 August 2005). In total, there have
been over 9400 samples, both hunter-kill and private samples, tested in Texas to
date, and no positives have been found.
SO, out of a total of 9,400 samples taken for CWD surveillance in TEXAS
since 2002 of both hunter-kill and private kill, ONLY 191 samples have been
taken in the most likely place one would find CWD i.e. the border where CWD has
been documented at TEXAS and New Mexico
latest map NM cwd old data
CWD in New Mexico ;
What is the Department doing to prevent the spread of CWD?
Chronic wasting disease (CWD) was recently detected in a mule deer from
Unit 34. Until 2005, CWD had only been found in Unit 19. With this discovery,
the Department will increase its surveillance of deer and elk harvested in Units
29, 30 and 34.
Lymph nodes and/or brain stems from every harvested deer and brain stems
from all elk taken in Unit 34 will be sampled.
snip...
CWD SURVEILLANCE TEXAS
SNIP...SEE FULL TEXT ;
2011 – 2012
Friday, October 28, 2011
CWD Herd Monitoring Program to be Enforced Jan. 2012 TEXAS
Greetings TAHC et al,
A kind greetings from Bacliff, Texas.
In reply to ;
Texas Animal Health Commission (TAHC) Announcement October 27, 2011
I kindly submit the following ;
***for anyone interested, here is some history of CWD along the Texas, New
Mexico border, and my attempt to keep up with it...terry
snip...
see history CWD Texas, New Mexico Border ;
Monday, March 26, 2012
3 CASES OF CWD FOUND NEW MEXICO MULE DEER SEVERAL MILES FROM TEXAS BORDER
Sunday, October 04, 2009
CWD NEW MEXICO SPREADING SOUTH TO TEXAS 2009 2009 Summary of Chronic
Wasting Disease in New Mexico New Mexico Department of Game and Fish
*****2015-2016***
Wednesday, February 10, 2016
*** Wisconsin Two deer that escaped farm had chronic wasting disease CWD
***
Sunday, January 17, 2016
*** Wisconsin Captive CWD Lotto Pays Out Again indemnity payment of
$298,770 for 228 white-tailed deer killed on farm ***
Friday, February 05, 2016
*** Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION
Detections in Farmed Cervids and Wild ***
Wednesday, May 25, 2016
USDA APHIS National Scrapie TSE Prion Eradication Program April 2016
Monthly Report Prion 2016 Tokyo Update
Saturday, May 28, 2016
Infection and detection of PrPCWD in soil from CWD infected farm in Korea
Prion 2016 Tokyo
Tuesday, May 31, 2016
Priority Interim Position Paper PROTECTING THE FOOD CHAIN FROM PRIONS
Perspectives
Tuesday, May 31, 2016
New insights in the transfusional risk assessment of variant
Creutzfeldt-Jakob Disease: Transfusional transmission of vCJD prions in the
absence of detectable abnormal prion protein
Prion 2016 Tokyo
WS-02
Scrapie in swine: A diagnostic challenge
Justin J Greenlee1, Robert A Kunkle1, Jodi D Smith1, Heather W. Greenlee2
1National Animal Disease Center, US Dept. of Agriculture, Agricultural
Research Service, United States; 2Iowa State University College of Veterinary
Medicine
A naturally occurring prion disease has not been recognized in swine, but
the agent of bovine spongiform encephalopathy does transmit to swine by
experimental routes. Swine are thought to have a robust species barrier when
exposed to the naturally occurring prion diseases of other species, but the
susceptibility of swine to the agent of sheep scrapie has not been thoroughly
tested.
Since swine can be fed rations containing ruminant derived components in
the United States and many other countries, we conducted this experiment to test
the susceptibility of swine to U.S. scrapie isolates by intracranial and oral
inoculation. Scrapie inoculum was a pooled 10% (w/v) homogenate derived from the
brains of clinically ill sheep from the 4th passage of a serial passage study of
the U.S scrapie agent (No. 13-7) through susceptible sheep that were homozygous
ARQ at prion protein residues 136, 154, and 171, respectively. Pigs were
inoculated intracranially (n=19) with a single 0.75 ml dose or orally (n=24)
with 15 ml repeated on 4 consecutive days. Necropsies were done on a subset of
animals at approximately six months post inoculation (PI), at the time the pigs
were expected to reach market weight. Remaining pigs were maintained and
monitored for clinical signs of TSE until study termination at 80 months PI or
when removed due to intercurrent disease (primarily lameness). Brain samples
were examined by immunohistochemistry (IHC), western blot (WB), and
enzyme-linked immunosorbent assay (ELISA). Brain tissue from a subset of pigs in
each inoculation group was used for bioassay in mice expressing porcine PRNP.
At six-months PI, no evidence of scrapie infection was noted by any
diagnostic method. However, at 51 months of incubation or greater, 5 animals
were positive by one or more methods: IHC (n=4), WB (n=3), or ELISA (n=5).
Interestingly, positive bioassay results were obtained from all inoculated
groups (oral and intracranial; market weight and end of study).
Swine inoculated with the agent of scrapie by the intracranial and oral
routes do not accumulate abnormal prion protein (PrPSc) to a level detectable by
IHC or WB by the time they reach typical market age and weight. However, strong
support for the fact that swine are potential hosts for the agent of scrapie
comes from positive bioassay from both intracranially and orally inoculated pigs
and multiple diagnostic methods demonstrating abnormal prion protein in
intracranially inoculated pigs with long incubation times.
Curriculum Vitae
Dr. Greenlee is Research Veterinary Medical Officer in the Virus and Prion
Research Unit at the National Animal Disease Center, US Department of
Agriculture, Agricultural Research Service. He applies his specialty in
veterinary anatomic pathology to focused research on the intra- and interspecies
transmission of prion diseases in livestock and the development of antemortem
diagnostic assays for prion diseases. In addition, knockout and transgenic mouse
models are used to complement ongoing experiments in livestock species. Dr.
Greenlee has publications in a number of topic areas including prion agent
decontamination, effects of PRNP genotype on susceptibility to the agent of
sheep scrapie, characterization of US scrapie strains, transmission of chronic
wasting disease to cervids and cattle, features of H-BSE associated with the
E211 K polymorphism, and the development of retinal assessment for antemortem
screening for prion diseases in sheep and cattle. Dr. Greenlee obtained his DVM
degree and completed the PhD/residency program in Veterinary Pathology at Iowa
State University. He is a Diplomate of the American College of Veterinary
Pathologists.
Saturday, April 23, 2016
SCRAPIE WS-01: Prion diseases in animals and zoonotic potential PRION 2016
TOKYO
Prion. 10:S15-S21. 2016 ISSN: 1933-6896 printl 1933-690X online
Animal and Plant Health Inspection Service (APHIS) Proposed Rule: Scrapie
in Sheep and Goats Singeltary submission
Wednesday, May 25, 2016
USDA APHIS National Scrapie TSE Prion Eradication Program April 2016
Monthly Report Prion 2016 Tokyo Update
see more here from PRION2015 Ft. Collins and more on zoonotic CWD ;
Monday, May 02, 2016
*** Zoonotic Potential of CWD Prions: An Update Prion 2016 Tokyo ***
Thursday, October 22, 2015
*** Former Ag Secretary Ann Veneman talks women in agriculture and we talk
mad cow disease USDA and what really happened in Texas ***
CJD/BSE (aka madcow) Human/Animal TSE’s--U.S.--Submission To Scientific
Advisors and Consultants Staff January 2001 Meeting (short version)
Freas, William
From: Terry S. Singeltary Sr. [flounder@wt.net]
Sent: Monday, January 08,2001 3:03 PM
TO: freas@CBS5055530.CBER.FDA.GOV
Subject: CJD/BSE (aka madcow) Human/Animal TSE’s--U.S.--Submission To
Scientific Advisors and Consultants Staff January 2001 Meeting (short
version)
CJD/BSE (aka madcow) Human/Animal TSE’s--U.S.--Submission To Scientific
Advisors and Consultants Staff January 2001 Meeting (short version)
Greetings again Dr. Freas and Committee Members,
I wish to submit the following information to the Scientific Advisors and
Consultants Staff 2001 Advisory Committee (short version).
I understand the reason of having to shorten my submission, but only hope
that you add it to a copy of the long version, for members to take and read at
their pleasure, (if cost is problem, bill me, address below). So when they
realize some time in the near future of the 'real' risks i speak of from
human/animal TSEs and blood/surgical products. I cannot explain the 'real' risk
of this in 5 or 10 minutes at some meeting, or on 2 or 3 pages, but will attempt
here:
remember AIDS/HIV, 'no problem to heterosexuals in the U.S.? no need to go
into that, you know of this blunder:
DO NOT make these same stupid mistakes again with human/animal TSE's aka
MADCOW DISEASE. I lost my Mom to hvCJD, and my neighbor lost his Mother to sCJD
as well (both cases confirmed). I have seen many deaths, from many diseases. I
have never seen anything as CJD, I still see my Mom laying helpless, jerking
tremendously, and screaming "God, what's wrong with me, why can't I stop this".
I still see this, and will never forget. Approximately 10 weeks from 1st of
symptoms to death. This is what drives me. I have learned more in 3 years about
not only human/animal TSE's but the cattle/rendering/feeding industry/government
than i ever wished to.
I think you are all aware of CJD vs vCJD, but i don't think you all know
the facts of human/animal TSE's as a whole, they are all very very similar, and
are all tied to the same thing, GREED and MAN.
I am beginning to think that the endless attempt to track down and ban,
potential victims from known BSE Countries from giving blood will be futile. You
would have to ban everyone on the Globe eventually? AS well, I think we MUST ACT
SWIFTLY to find blood test for TSE's, whether it be blood test, urine test,
.eyelid test, anything at whatever cost, we need a test FAST.
DO NOT let the incubation time period of these TSEs fool you.
To think of Scrapie as the prime agent to compare CJD, but yet overlook the
Louping-ill vaccine event in 1930's of which 1000's of sheep where infected by
scrapie from a vaccine made of scrapie infected sheep brains, would be foolish.
I acquired this full text version of the event which was recorded in the Annual
Congress of 1946 National Vet. Med. Ass. of Great Britain and Ireland. from the
BVA and the URL is posted in my (long version).
U.S.A. should make all human/animal TSE's notifiable at all ages, with
requirements for a thorough surveillance and post-mortem examinations free of
charge, if you are serious about eradicating this horrible disease in man and
animal.
There is histopathology reports describing o florid plaques" in CJD victims
in the USA and some of these victims are getting younger. I have copies of such
autopsies, there has to be more. PLUS, sub-clinical human TSE's will most
definitely be a problem.
THEN think of vaccineCJD in children and the bovine tissues used in the
manufacturing process, think of the FACT that this agent surviving 6OO*C. PNAS
-- Brown et al. 97 (7): 3418 scrapie agent live at 600*C
Then think of the CONFIDENTIAL documents of what was known of human/animal
TSE and vaccines in the mid to late 80s, it was all about depletion of stock, to
hell with the kids, BUT yet they knew. To think of the recall and worry of TSE's
from the polio vaccine, (one taken orally i think?), but yet neglect to act on
the other potential TSE vaccines (inoculations, the most effective mode to
transmit TSEs) of which thousands of doses were kept and used, to deplete
stockpile, again would be foolish.
--Oral polio; up to 1988, foetal calf serum was used from UK and New
Zealand (pooled); since 1988 foetal calf serum only from New Zealand. Large
stocks are held.
--Rubella; bulk was made before 1979 from foetal calf serum from UK and New
Zealand. None has been made as there are some 15 years stock.
--Diphtheria; UK bovine beef muscle and ox heart is used but since the end
of 1988 this has been sourced from Eire. There are 1,250 litres of stock.
--Tetanus; this involves bovine material from the UK mainly Scottish. There
are 21,000 litres of stock.
--Pertussis; uses bovine material from the UK. There are 63,000 litres of
stock. --They consider that to switch to a non-UK source will take a minimum of
6-18 months and to switch to a non-bovine source will take a minimum of five
years.
3. XXXXXXXXXXX have measles, mumps, MMR, rubella vaccines. These are
sourced from the USA and the company believes that US material only is
used.
89/2.14/2.1
============
BSE3/1 0251
4. XXXXXXXXXXX have a measles vaccine using bovine serum from the UK. there
are 440,000 units of stock. They have also got MMR using bovine serum from the
UK.
5. XXXXXXXXXXX have influenza, rubella, measles,' MMR vaccines likely to be
used in children. Of those they think that only MMR contains bovine material
which is probably a French origin.
6. XXXXXXXXXXX have diphtheria/tetanus and potasses on clinical trial. hese
use veal material, some of which has come from the UK and has been ade by
XXXXXXXXXXX (see above).
I have documents of imports from known BSE Countries, of ferments, whole
blood, antiallergenic preparations,
2
human blood plasma, normal human blood sera, human immune blood sera, fetal
bovine serum, and other blood fractions not elsewhere specified or included,
imported glands, catgut, vaccines for both human/animal, as late as 1998. Let us
not forget about PITUITARY EXTRACT. This was used to help COWS super ovulate.
This tissue was considered to be of greatest risk of containing BSE and
consequently transmitting the disease.
ANNEX 6
MEETING HELD ON 8 JUNE 1988 TO DISCUSS THE IMPLICATIONS OF BSE TO
BIOLOGICAL PRODUCTS CONTAINING BOVINE - EXTRACTED MATERIAL
How much of this was used in the U.S.?
Please do not keep making the same mistakes; 'Absence of evidence is not
evidence of absence'.
What are the U.S. rules for importing and manufacturing vaccines, medicines
and medical devices?
Does the U.S.A. allow sourcing of raw material of ruminants from the
U.S.A.?
U.S. cattle, what kind of guarantee can you give for serum or tissue donor
herds? . The U.S. rendering system would easily amplify T.S.E.'s:
Have we increased the stability of the system (improved heat treatments)
since the EU SSC report on the U.S.A. was published in july 2000?
What is done to avoid cross-contaminations in the U.S.A.?
How can the U.S. control absence of cross-contaminations of animal TSE's
when pig and horse MBM and even deer and elk are allowed in ruminant feed, as
well as bovine blood? I sadly think of the rendering and feeding policy before
the Aug. 4, 1997 'partial' feed ban, where anything went, from the city police
horse, to the circus elephant, i will not mention all the scrapie infected
sheep. I am surprised that we have not included man 'aka soyent green'. It is a
disgusting industry and nothing more than greed fuels it.
When will the U.S.. start real surveillance of the U.S. bovine population
(not passive, this will not work)?
When will U.S. start removing SRMs?
Have they stopped the use of pneumatic stunners in the U.S.?
If so, will we stop it in all U.S. abattoirs or only in those abattoirs
exporting to Europe?
If not, WHY NOT?
same questions for removal of SRM in the U.S.A., or just for export?
If not, WHY NOT?
How do we now sterilize surgical/dental instruments in the U.S.A.?
Where have we been sourcing surgical catgut?
(i have copies of imports to U.S., and it would floor you) hen will
re-usable surgical instruments be banned?
'Unregulated "foods" such as 'nutritional supplements' containing various
extracts from ruminants, whether imported or derived from
3
US cattle/sheep/cervids ("antler velvet" extracts!) should be forbidden or
at least very seriously regulated. (neighbors Mom, whom also died from CJD, had
been taking bovine based supplement, which contained brain, eye, and many other
bovine/ovine tissues for years, 'IPLEX').
What is the use of banning blood or tissue donors from Germany, France,
etc... when the U.S.A. continues exposing cattle, sheep and people to SRM,
refuses to have a serious feed ban, refuses to do systematic
BSE-surveillance?
The FDA should feel responsible for the safety of what people eat, prohibit
the most dangerous foods, not only prohibit a few more donors - the FDA should
be responsible for the safe sourcing of medical devices, not only rely on
banning donors "from Europe", The 'real' risks are here in the U.S. as well, and
nave been for some time.
We must not forget the studies that have proven infectivity in blood from
TSE's.
The Lancet, November 9, 1985
Sir, --Professor Manuelidis and his colleagues (Oct 19, p896) report
transmission to animals of Creutzfeldt-Jakob disease (CJD) from the buffy coat
from two patients. We also transmitted the disease from, whole blood samples of
a patient (and of mice) infected with CJD.l Brain, Cornea, and urine from this
patient were also infectious, and the clinicopathological findings2 are
summarised as follows.
snip...
Samples,were taken aseptically at necropsy. 10% crude homogenates of brain
and cornea in saline, whole blood (after crushing a clot), and untreated CSF and
urine were innoculated intracerebrally into CFl strain mice (20 ul per animal).
Some mice showed emaciation, bradykinesia, rigidity of the body and tail, and
sometimes tremor after long incubation periods. Tissues obtained after the
animal died (or was killed) were studied histologically (table). Animals
infected by various inocula showed common pathological changes, consisting of
severe spongiform changes, glial proliferation, and a moderate loss of nerve
cells. A few mice inoculated with brain tissue or urine had the same amyloid
plaques found in patients and animals with CJD.3
snip...
Department of Neuropathology,. Neurological Institute, Faculty of Medicine,
Kyushu University, Fukuoka812, Japan JUN TATEISHI
(full text-long version)
and
CWD and transmission to man will be no different than other TSE's.
"Clearly, it is premature to draw firm conclusions about CWD passing
naturally into humans, cattle and sheep, but the present results suggest that
CWD transmissions to humans would be as limited by PrP incompatibility as
transmissions of BSE or sheep scrapie to humans. Although there is no evidence
that sheep scrapie has affected humans, it is likely that BSE has
4
caused variant CJD in 74 people (definite and probable variant CJD cases to
date according to the UK CJD Surveillance Unit). Given the presumably large
number of people exposed to BSE infectivity, the susceptibility of humans may
still be very low compared with cattle, which would be consistent with the
relatively inefficient conversion of human PrP-sen by PrPBSE. Nonetheless, since
humans have apparently been infected by BSE, it would seem prudent to take
reasonable measures to limit exposure of humans (as well as sheep and cattle) to
CWD infectivity as has been recommended for other animal TSEs,"
G.J. Raymond1, A. Bossers2, L.D. Raymond1, K.I. O'Rourke3, L.E. McHolland4,
P.K. Bryant III4, M.W. Miller5, E.S. Williams6, M. Smits2 and B.
Caughey1,7
or more recently transmission of BSE to sheep via whole blood Research
letters Volume 356, Number 9234 16 September 2000
Transmission of BSE by blood transfusion in sheep
Lancet 2000; 356: 999 – 1000
F Houston, J D Foster, Angela Chong, N Hunter, C J Bostock
See Commentary
"We have shown that it is possible to transmit bovine spongiform
encephalopathy (BSE) to a sheep by transfusion with whole blood taken from
another sheep during the symptom-free phase of an experimental BSE infection.
BSE and variant Creutzfeldt-Jakob disease (vCJD) in human beings are caused by
the same infectious agent, and the sheep-BSE experimental model has a similar
pathogenesis to that of human vCJD. Although UK blood transfusions are
leucodepleted--a possible protective measure against any risk from blood
transmission-- this report suggests that blood donated by symptom-free
vCJD-infected human beings may represent a risk of spread of vCJD infection
among the human population of the UK."
"The demonstration that the new variant of Creutzfeldt-Jakob disease (vCJD)
is caused by the same agent that causes bovine spongiform encephalopathy (BSE)
in cattle1 has raised concerns that blood from human beings in the symptom-free
stages of vCJD could transmit infection to recipients of blood transfusions
(full text long version)"
and...
"The large number of cases (1040), temporal clustering of the outbreaks (15
in the first 6 months of 1997), the high in-flock incidence, and the exceptional
involvement of goats (390 cases), suggested an accidental infection. The source
of the epidemic might have been TSE-contaminated meat and bonemeal, but eight
flocks had never been fed any commercial feedstuff. Infection might have risen
from the use of a formol-inactivated vaccine against contagious agalactia
prepared by a single laboratory with brain and mammary gland homogenates of
sheep infected with Mycoplasma agalactiae. Although clinical signs of TSE in the
donor sheep have not been found, it is possible that one or more of them were
harbouring the
5
infectious agent. Between 1995 and 1996, this vaccine was given
subcutaneously to 15 of the affected flocks (to one flock in 1994) ; in these
animals the disease appeared between 23 and 35 months after vaccination. No
information is available for herd 13 because it was made up of stolen animals.
Sheep from the remaining three flocks (1-3, figure) did not receive the vaccine,
thus suggesting a naturally occurring disease.’’ (again, full text long
version).
IN SHORT, please do under estimate this data and or human/animal TSE's
including CWD in the U.S.A.
A few last words, please.
The cattle industry would love to have us turn our focus to CWD and forget
about our own home grown TSE in Bovines. This would be easy to do. Marsh's work
was from downer cattle feed, NOT downer deer/elk feed. This has been
proven.
DO NOT MAKE THAT MISTAKE.
There should be NO LESS THAN 1,000,000 tests for BSE/TSE ' in 2001 for
U.S.A. French are testing 20,000 a week. The tests are available. Why wait until
we stumble across a case from passive surveillance, by then it is to late. IF we
want the truth, this is a must???
United States Total ,Bovine Brain Submissions by State,
May 10 ,1990 thru October 31, 2000
Total 11,700
FROM 1.5 BILLION HEAD OF CATTLE since 1990 ???
with same feeding and rendering practices as that of U.K. for years and
years, same scrapie infected sheep used in feed, for years and years, 950
scrapie infect FLOCKS in the U.S. and over 20 different strains of scrapie known
to date. (hmmm, i am thinking why there is not a variant scrapie, that is
totally different than all the rest)? just being sarcastic.
with only PARTIAL FEED BAN implemented on Aug. 4, 1997??? (you really need
to reconsider that blood meal etc. 'TOTAL BAN')
AND PLEASE FOR GODS SAKE, STOP saying vCJD victims are the only ones tied
to this environmental death sentence. "PROVE IT". It's just not true. The
'CHOSEN ONES' are not the only ones dying because of this man-made death
sentence. When making regulations for human health from human/animal TSEs, you
had better include ALL human TSE's, not just vCJD. Do NOT underestimate sporadic
CJD with the 'prehistoric' testing available to date. This could be a deadly
mistake. Remember, sCJD kills much faster from 1st onset of symptoms to death,
and hvCJD is the fastest. Could it just be a higher titre of infectivity, or
route or source, or all three?
Last, but not least. The illegal/legal harvesting of body parts and tissues
will come back to haunt you. Maybe not morally, but due to NO background checks
and human TSEs, again it will continue to spread.
Stupidity, Ignorance and Greed is what fuels this disease. You must stop
all of this, and ACT AT ONCE...
Sent: Monday, January 08,2001 3:03 PM
TO: freas@CBS5055530.CBER.FDA.GOV
FDA CJD BSE TSE Prion Scientific Advisors and Consultants Staff January
2001 Meeting Singeltary Submission
2001 FDA CJD TSE Prion Singeltary Submission
15 November 1999
British Medical Journal
vCJD in the USA * BSE in U.S.
2 January 2000
British Medical Journal
U.S. Scientist should be concerned with a CJD epidemic in the U.S., as well
Diagnosis and Reporting of Creutzfeldt-Jakob Disease
Singeltary, Sr et al. JAMA.2001; 285: 733-734. Vol. 285 No. 6, February 14,
2001 JAMA
Diagnosis and Reporting of Creutzfeldt-Jakob Disease
To the Editor: In their Research Letter, Dr Gibbons and colleagues1
reported that the annual US death rate due to Creutzfeldt-Jakob disease (CJD)
has been stable since 1985. These estimates, however, are based only on reported
cases, and do not include misdiagnosed or preclinical cases. It seems to me that
misdiagnosis alone would drastically change these figures. An unknown number of
persons with a diagnosis of Alzheimer disease in fact may have CJD, although
only a small number of these patients receive the postmortem examination
necessary to make this diagnosis. Furthermore, only a few states have made CJD
reportable. Human and animal transmissible spongiform encephalopathies should be
reportable nationwide and internationally.
Terry S. Singeltary, Sr Bacliff, Tex
1. Gibbons RV, Holman RC, Belay ED, Schonberger LB. Creutzfeldt-Jakob
disease in the United States: 1979-1998. JAMA. 2000;284:2322-2323.
26 March 2003
Terry S. Singeltary, retired (medically) CJD WATCH
I lost my mother to hvCJD (Heidenhain Variant CJD). I would like to comment
on the CDC's attempts to monitor the occurrence of emerging forms of CJD.
Asante, Collinge et al [1] have reported that BSE transmission to the
129-methionine genotype can lead to an alternate phenotype that is
indistinguishable from type 2 PrPSc, the commonest sporadic CJD. However, CJD
and all human TSEs are not reportable nationally. CJD and all human TSEs must be
made reportable in every state and internationally. I hope that the CDC does not
continue to expect us to still believe that the 85%+ of all CJD cases which are
sporadic are all spontaneous, without route/source. We have many TSEs in the USA
in both animal and man. CWD in deer/elk is spreading rapidly and CWD does
transmit to mink, ferret, cattle, and squirrel monkey by intracerebral
inoculation. With the known incubation periods in other TSEs, oral transmission
studies of CWD may take much longer. Every victim/family of CJD/TSEs should be
asked about route and source of this agent. To prolong this will only spread the
agent and needlessly expose others. In light of the findings of Asante and
Collinge et al, there should be drastic measures to safeguard the medical and
surgical arena from sporadic CJDs and all human TSEs. I only ponder how many
sporadic CJDs in the USA are type 2 PrPSc?
The Lancet Infectious Diseases, Volume 3, Issue 8, Page 463, August 2003
doi:10.1016/S1473-3099(03)00715-1Cite or Link Using DOI
Tracking spongiform encephalopathies in North America
Original
Xavier Bosch
“My name is Terry S Singeltary Sr, and I live in Bacliff, Texas. I lost my
mom to hvCJD (Heidenhain variant CJD) and have been searching for answers ever
since. What I have found is that we have not been told the truth. CWD in deer
and elk is a small portion of a much bigger problem.” 49-year—old Singeltary is
one of a number of people who have remained largely unsatisfied after being told
that a close relative died from a rapidly progressive dementia compatible with
spontaneous Creutzfeldt—Jakob ...
*** Singeltary reply PLoS ; RE-Molecular, Biochemical and Genetic
Characteristics of BSE in Canada Posted by flounder on 19 May 2010 at 21:21 GMT
31 Jan 2015 at 20:14 GMT
*** Ruminant feed ban for cervids in the United States? ***
31 Jan 2015 at 20:14 GMT
see Singeltary comment ;
*** IBNC Tauopathy or TSE Prion disease, it appears, no one is sure ***
PLoS
Posted by Terry S. Singeltary Sr. on 03 Jul 2015 at 16:53 GMT
*** Singeltary comment PLoS ***
Alzheimer’s disease and Transmissible Spongiform Encephalopathy prion
disease, Iatrogenic, what if ?
Posted by flounder on 05 Nov 2014 at 21:27 GMT
Previous article Nature | Letter
Arithmetic and local circuitry underlying dopamine prediction errors Next
article Nature | Letter
Single-cell messenger RNA sequencing reveals rare intestinal cell types
Evidence for human transmission of amyloid-β pathology and cerebral amyloid
angiopathy Zane Jaunmuktane,1, Simon Mead,2, 3, 4, Matthew Ellis,3, Jonathan D.
F. Wadsworth,2, 3, Andrew J. Nicoll,2, 3, Joanna Kenny,2, 4, Francesca
Launchbury,3, Jacqueline Linehan,2, Angela Richard-Loendt,3, A. Sarah Walker,5,
Peter Rudge,2, 4, John Collinge2, 3, 4, & Sebastian Brandner1, 2, 3,
Affiliations Contributions Corresponding authors Journal name: Nature Volume:
525, Pages: 247–250 Date published: (10 September 2015) DOI:
doi:10.1038/nature15369 Received 26 April 2015 Accepted 14 August 2015 Published
online 09 September 2015 Updated online 11 September 2015 Erratum (October,
2015)
see Singeltary Comment ;
Alzheimer-type brain pathology may be transmitted by grafts of dura mater
26/01/2016
Singeltary Comment ;
Terry S. Singeltary Sr.
posted by Terry S. Singeltary Sr. at
10:39 AM
0 Comments:
Post a Comment
Subscribe to Post Comments [Atom]
<< Home