Saturday, December 23, 2017

Missouri CWD TSE Prion 2017-2018 SAMPLING RESULTS TO DATE 3 POSITIVE

2017-2018 SAMPLING RESULTS TO DATE

The table shows MDC sampling efforts and test results so far for the current sampling season. A CWD surveillance season runs from July 1 through June 30 the following year.
AreaCWD Not DetectedCWD PositiveResults PendingTotal
Inside CWD Management Zone140103472318736
Statewide (Outside of Zone)63505541189
TOTAL146453527719925
See the below table for a breakdown of where positives have occurred this surveillance season.

CWD Positives by County

CountyPositives
Cedar1
Polk1
Saint Clair1
This map shows cases of CWD found so far in free-ranging deer.

ONGOING STATEWIDE TESTING

  • MDC began statewide CWD surveillance of free-ranging deer in 2002 when the deadly disease began spreading to nearby states.
  • MDC has tested more than 76,600 free-ranging deer tested so far.
  • MDC continues to test deer on a statewide level to help detect new areas of infection as soon as possible.
  • MDC works with taxidermists in about half of the state each year – alternating the north half and south half. MDC also tests deer around the state that appear sick.

2016-2017 SAMPLING RESULTS

  • Last season, MDC tested more than 25,600 deer for CWD.
  • Mandatory sampling results showed five deer positive for CWD. Four additional deer tested positive from other sampling efforts for a total of 9 for the season.
  • About 19,200 of the tissue samples collected were through mandatory sampling activities during the opening weekend of 2016 Fall Firearms Deer Season in the 29 counties (at the time) of the CWD Management Zone.
  • About 3,200 of the total samples were collected from outside the CWD Management Zone as part of ongoing statewide CWD surveillance efforts.
  • Remaining samples were collected through targeted follow-up activities near where CWD has been detected and other efforts.

CWD CASES FOUND IN FREE-RANGING DEER

This table shows the number of CWD cases found in Missouri free-ranging deer by year and county prior to the current testing season.
CWD Detections Through June 30, 2017.
County2011-122012-132013-142014-152015-162016-17County Totals
Totals550167942
Adair   63110
Cole   1  1
Franklin    134
Jefferson     11
Linn    1 1
Macon55092223
St. Clair     22

CWD SAMPLING NEAR ARKANSAS

More than 200 cases of CWD have been found in deer and elk in northwest Arkansas since early 2016. This has prompted MDC to increase CWD surveillance efforts in southwest Missouri. No deer from southern Missouri have tested positive for the disease.

FIRST CASES OF CWD IN MISSOURI

The first cases of CWD in Missouri were detected in 2010 and 2011 in captive deer at private big-game breeding and hunting facilities in Linn and Macon counties. A total of 11 cases were confirmed in captive deer at the facilities.

WHAT MDC IS DOING TO SLOW THE SPREAD OF CWD

  • MDC works with hunters, landowners, taxidermists, and others through mandatory and voluntary sampling to collect tissue samples for CWD testing in areas where CWD has been found.
  • MDC conducts broader, ongoing statewide testing for CWD and focuses on one-half of the state each year.
  • MDC has removed the antler-point restriction for counties in the CWD Management Zone because young bucks can spread the disease to new areas as they search for territory and mates.
  • MDC allows the use of two firearms antlerless permits in counties in the CWD Management Zone to help prevent undesired population increases in local deer numbers.
  • MDC has restricted feeding deer and placing minerals for deer in counties of the CWD Management Zone.
  • MDC strongly discourages the removal of deer carcasses from counties in the CWD Management Zone.
  • MDC encourages people to report sick deer to local staff.

WHAT PEOPLE CAN DO TO HELP

  • Have deer harvested in the CWD Management Zone tested for CWD through mandatory or voluntary sampling opportunities.
  • Do not move deer carcasses out of the CWD Management Zone.
  • Do not feed deer or place minerals for deer.
  • Report deer that look sick or are acting strange to MDC conservation agents or regional offices.

GET MORE INFORMATION

Call MDC at 573-815-7900 or email questions to CWDinfo@mdc.mo.gov(link sends e-mail).
SATURDAY, MAY 20, 2017 
Missouri CWD TSE PRION Surveillance and Monitoring
THURSDAY, MARCH 09, 2017 
Missouri MDC REPORTS TWO CASES OF CWD IN ST. CLAIR COUNTY
SUNDAY, MARCH 06, 2016 
Missouri 2015-2016 CWD Surveillance Summary to Date, with confirmed cases mounting
MONDAY, SEPTEMBER 28, 2015 
MISSOURI CHRONIC WASTING DISEASE CWD TSE PRION UPDATE
THURSDAY, MAY 15, 2014 
Missouri Stripping MDC regulatory authority of deer farms SB 506 HOW THEY VOTED Singeltary letter to Governor Nixon
*** Subject: USA CJD, BSE, SCRAPIE, CWD, TSE PRION END OF YEAR REPORTS 2017

THURSDAY, DECEMBER 14, 2017 

Governor Scott Walkers Apathy Condemns Wisconsin to a lifetime of Chronic Wasting Disease CWD TSE Prion aka Mad Deer Disease


FRIDAY, DECEMBER 15, 2017 

Pennsylvania Four Deer Test Positive for Chronic Wasting Disease on Franklin, Fulton County Quarantined Hunting Preserves

 
TUESDAY, DECEMBER 12, 2017 

Chronic Wasting Disease CWD TSE Prion (aka mad deer disease) Update USA December 14, 2017

(zoonosis and environmental risk factors towards the bottom, after state by state reports)


FRIDAY, DECEMBER 15, 2017

Canada CFIA updating its national CWD TSE PRION efforts to eradicate disease farmed cervid NOT successful December 14, 2017


CDC STRONGLY SUGGEST IN 2017;

Do not shoot, handle or eat meat from deer and elk that look sick or are acting strangely or are found dead (road-kill). When field-dressing a deer: Wear latex or rubber gloves when dressing the animal or handling the meat. Minimize how much you handle the organs of the animal, particularly the brain or spinal cord tissues. Do not use household knives or other kitchen utensils for field dressing. Check state wildlife and public health guidance to see whether testing of animals is recommended or required. Recommendations vary by state, but information about testing is available from many state wildlife agencies. Strongly consider having the deer or elk tested for CWD before you eat the meat. If you have your deer or elk commercially processed, consider asking that your animal be processed individually to avoid mixing meat from multiple animals. If your animal tests positive for CWD, do not eat meat from that animal. 

SEE FULL REPORT BELOW!

SUNDAY, DECEMBER 10, 2017 

Detection of Prions in Blood of Cervids at the Asymptomatic Stage of Chronic Wasting Disease

The results showed a sensitivity of 100% in animals with very poor body condition that were IHC-positive in both brain and lymph nodes, 96% in asymptomatic deer IHC-positive in brain and lymph nodes and 53% in animals at early stages of infection that were IHC-positive only in lymph nodes. The overall mean diagnostic sensitivity was 79.3% with 100% specificity. These findings show that PMCA might be useful as a blood test for routine, live animal diagnosis of CWD.



CHRONIC WASTING DISEASE CWD TSE PRION ZOONOTIC ZOONOSIS

PRICE OF TSE PRION POKER GOES UP!

2017

Subject: ***CDC Now Recommends Strongly consider having the deer or elk tested for CWD before you eat the meat

CDC Now Recommends Strongly consider having the deer or elk tested for CWD before you eat the meat 

Chronic Wasting Disease (CWD) 

Prevention 

If CWD could spread to people, it would most likely be through eating of infected deer and elk. In a 2006-2007 CDC survey of U.S. residents, nearly 20 percent of those surveyed said they had hunted deer or elk and more than two-thirds said they had eaten venison or elk meat. However, to date, no CWD infections have been reported in people. 

Hunters must consider many factors when determining whether to eat meat from deer and elk harvested from areas with CWD, including the level of risk they are willing to accept. Hunters harvesting wild deer and elk from areas with reported CWD should check state wildlife and public health guidance to see whether testing of animals is recommended or required in a given state or region. In areas where CWD is known to be present, CDC recommends that hunters strongly consider having those animals tested before eating the meat. 

Tests for CWD are monitoring tools that some state wildlife officials use to look at the rates of CWD in certain animal populations. Testing may not be available in every state, and states may use these tests in different ways. A negative test result does not guarantee that an individual animal is not infected with CWD, but it does make it considerably less likely and may reduce your risk of exposure to CWD. 

To be as safe as possible and decrease their potential risk of exposure to CWD, hunters should take the following steps when hunting in areas with CWD: 

Do not shoot, handle or eat meat from deer and elk that look sick or are acting strangely or are found dead (road-kill). When field-dressing a deer: Wear latex or rubber gloves when dressing the animal or handling the meat. Minimize how much you handle the organs of the animal, particularly the brain or spinal cord tissues. Do not use household knives or other kitchen utensils for field dressing. Check state wildlife and public health guidance to see whether testing of animals is recommended or required. Recommendations vary by state, but information about testing is available from many state wildlife agencies. Strongly consider having the deer or elk tested for CWD before you eat the meat. If you have your deer or elk commercially processed, consider asking that your animal be processed individually to avoid mixing meat from multiple animals. If your animal tests positive for CWD, do not eat meat from that animal. The U.S. Department of Agriculture’s Animal and Plant Health Inspection Service regulates commercially farmed deer and elk. The agency operates a national CWD herd certification program. As part of the voluntary program, states and individual herd owners agree to meet requirements meant to decrease the risk of CWD in their herds. Privately owned herds that do not participate in the herd certification program may be at increased risk for CWD. 

Page last reviewed: August 17, 2017 Page last updated: August 17, 2017 Content source: Centers for Disease Control and Prevention National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) Division of High-Consequence Pathogens and Pathology (DHCPP) 


 > However, to date, no CWD infections have been reported in people. 

key word here is 'reported'. science has shown that CWD in humans will look like sporadic CJD. SO, how can one assume that CWD has not already transmitted to humans? they can't, and it's as simple as that. from all recorded science to date, CWD has already transmitted to humans, and it's being misdiagnosed as sporadic CJD. ...terry 

LOOKING FOR CWD IN HUMANS AS nvCJD or as an ATYPICAL CJD, LOOKING IN ALL THE WRONG PLACES $$$ 

*** These results would seem to suggest that CWD does indeed have zoonotic potential, at least as judged by the compatibility of CWD prions and their human PrPC target. Furthermore, extrapolation from this simple in vitro assay suggests that if zoonotic CWD occurred, it would most likely effect those of the PRNP codon 129-MM genotype and that the PrPres type would be similar to that found in the most common subtype of sCJD (MM1).*** 




TUESDAY, SEPTEMBER 12, 2017 

CDC Now Recommends Strongly consider having the deer or elk tested for CWD before you eat the meat 


Prion 2017 Conference Abstracts CWD

 2017 PRION CONFERENCE 

First evidence of intracranial and peroral transmission of Chronic Wasting Disease (CWD) into Cynomolgus macaques: a work in progress 

Stefanie Czub1, Walter Schulz-Schaeffer2, Christiane Stahl-Hennig3, Michael Beekes4, Hermann Schaetzl5 and Dirk Motzkus6 1 

University of Calgary Faculty of Veterinary Medicine/Canadian Food Inspection Agency; 2Universitatsklinikum des Saarlandes und Medizinische Fakultat der Universitat des Saarlandes; 3 Deutsches Primaten Zentrum/Goettingen; 4 Robert-Koch-Institut Berlin; 5 University of Calgary Faculty of Veterinary Medicine; 6 presently: Boehringer Ingelheim Veterinary Research Center; previously: Deutsches Primaten Zentrum/Goettingen 

This is a progress report of a project which started in 2009. 21 cynomolgus macaques were challenged with characterized CWD material from white-tailed deer (WTD) or elk by intracerebral (ic), oral, and skin exposure routes. Additional blood transfusion experiments are supposed to assess the CWD contamination risk of human blood product. Challenge materials originated from symptomatic cervids for ic, skin scarification and partially per oral routes (WTD brain). Challenge material for feeding of muscle derived from preclinical WTD and from preclinical macaques for blood transfusion experiments. We have confirmed that the CWD challenge material contained at least two different CWD agents (brain material) as well as CWD prions in muscle-associated nerves. 

Here we present first data on a group of animals either challenged ic with steel wires or per orally and sacrificed with incubation times ranging from 4.5 to 6.9 years at postmortem. Three animals displayed signs of mild clinical disease, including anxiety, apathy, ataxia and/or tremor. In four animals wasting was observed, two of those had confirmed diabetes. All animals have variable signs of prion neuropathology in spinal cords and brains and by supersensitive IHC, reaction was detected in spinal cord segments of all animals. Protein misfolding cyclic amplification (PMCA), real-time quaking-induced conversion (RT-QuiC) and PET-blot assays to further substantiate these findings are on the way, as well as bioassays in bank voles and transgenic mice. 

At present, a total of 10 animals are sacrificed and read-outs are ongoing. Preclinical incubation of the remaining macaques covers a range from 6.4 to 7.10 years. Based on the species barrier and an incubation time of > 5 years for BSE in macaques and about 10 years for scrapie in macaques, we expected an onset of clinical disease beyond 6 years post inoculation. 

PRION 2017 DECIPHERING NEURODEGENERATIVE DISORDERS 

Subject: PRION 2017 CONFERENCE DECIPHERING NEURODEGENERATIVE DISORDERS VIDEO 

PRION 2017 CONFERENCE DECIPHERING NEURODEGENERATIVE DISORDERS 

*** PRION 2017 CONFERENCE VIDEO 



TUESDAY, JULY 04, 2017

*** PRION 2017 CONFERENCE ABSTRACTS ON CHRONIC WASTING DISEASE CWD TSE PRION ***


TUESDAY, DECEMBER 12, 2017 

Bovine Spongiform Encephalopathy BSE TSE Prion (aka mad cow disease) Report December 14, 2017 2017


TUESDAY, DECEMBER 12, 2017 

SCRAPIE TSE PRION UPDATE USA DECEMBER 14, 2017


TUESDAY, DECEMBER 12, 2017 

Creutzfeldt Jakob Disease CJD National Prion Disease Pathology Surveillance Center Cases Examined to December 14, 2017


Tuesday, December 12, 2017 

Neuropathology of iatrogenic Creutzfeldt–Jakob disease and immunoassay of French cadaver-sourced growth hormone batches suggest possible transmission of tauopathy and long incubation periods for the transmission of Abeta pathology



TERRY S. SINGELTARY SR.

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