The battle against Chronic Wasting Disease continues in Southeast Iowa
Subject: The battle against Chronic Wasting Disease continues in Southeast
Iowa
DAVIS COUNTY, IOWA -- The battle against Chronic Wasting Disease continues
in Southeast Iowa.
After deer at the Pine Ridge Hunting Preserve in Davis County tested
positive for CWD, the area was supposed to be quarantined to prevent it from
being spread further. Even though the animals are now gone from the area, it's
been brought to light that the gates to the facility have been left open,
sometimes chained open, supposedly by the landowner, which raises the risk of
CWD being spread into the surrounding area.
"This is just appalling because you have a highly contaminated area that is
quarantined to prevent the spread of a highly contagious disease to the wild
herd and here you have the gates of a contaminated facility - a quarantined
contaminated facility - open," said State Representative Curt Hanson. "In my
opinion, that's just irresponsible."
If the disease spreads into the wild herd, it could have a detrimental
domino effect -- not just on the deer population, but on Iowa's hunting
economy.
"Right now, it's only in the captive herd, we do not wish to have this
spread to the wild herd," Hanson said. "There would be very large consequences,
many of them economic."
"It would have quite an effect upon our hunting in the state and the amount
of revenue and things that the DNR brings in from the hunters to come into the
state of Iowa," said State Representative Mary Gaskill. "[Getting] their deer
license and people will quit hunting if they're fearful that they're not getting
good deer."
Hanson said he was not offered an explanation as to why the gates were left
open, but both he and Gaskill are working with the DNR and the Attorney
General's Office to remedy the situation.
The Attorney General's Office will hopefully be looking into legal options
to protect neighbors and residents near the facility.
Hanson said, ideally, the DNR will check in on the reserve periodically to
make sure the quarantine is being executed correctly.
Wednesday, May 15, 2013
Intranasal Inoculation of White-Tailed Deer (Odocoileus virginianus) with
Lyophilized Chronic Wasting Disease Prion Particulate Complexed to
Montmorillonite Clay
Research Article
Tuesday, October 23, 2012
PA Captive deer from CWD-positive farm roaming free
HERE, we see why these shooting pen owners some much like the USDA
oversight of these game farms ;
USDA TO PGC ONCE CAPTIVES ESCAPE "it‘s no longer its business.” problem
solved $$$...TSS
Sunday, January 06, 2013
USDA TO PGC ONCE CAPTIVES ESCAPE "it‘s no longer its business.”
what happened to the PA deer from the CWD index heard that went to
Louisiana ??? or Indiana ???
Tuesday, May 28, 2013
Chronic Wasting Disease CWD quarantine Louisiana via CWD index herd
Pennsylvania Update May 28, 2013
6 doe from Pennsylvania CWD index herd still on the loose in Louisiana,
quarantine began on October 18, 2012, still ongoing, Lake Charles premises.
Tuesday, April 16, 2013
Cervid Industry Unites To Set Direction for CWD Reform and seem to ignore
their ignorance and denial in their role in spreading Chronic Wasting
Disease
how many states have $465,000., and can quarantine and purchase there from,
each cwd said infected farm, but how many states can afford this for all the cwd
infected cervid game ranch type farms ???
T
uesday, December 20, 2011
CHRONIC WASTING DISEASE CWD WISCONSIN Almond Deer (Buckhorn Flats) Farm
Update DECEMBER 2011
The CWD infection rate was nearly 80%, the highest ever in a North American
captive herd.
RECOMMENDATION: That the Board approve the purchase of 80 acres of land for
$465,000 for the Statewide Wildlife Habitat Program in Portage County and
approve the restrictions on public use of the site.
SUMMARY:
pens, PENS, PENS ???
*** Spraker suggested an interesting explanation for the occurrence of CWD.
The deer pens at the Foot Hills Campus were built some 30-40 years ago by a Dr.
Bob Davis. At or abut that time, allegedly, some scrapie work was conducted at
this site. When deer were introduced to the pens they occupied ground that had
previously been occupied by sheep.
now, decades later ;
2012
PO-039: A comparison of scrapie and chronic wasting disease in white-tailed
deer
Justin Greenlee, Jodi Smith, Eric Nicholson US Dept. Agriculture;
Agricultural Research Service, National Animal Disease Center; Ames, IA USA
Interspecies transmission studies afford the opportunity to better
understand the potential host range and origins of prion diseases. The purpose
of these experiments was to determine susceptibility of white-tailed deer (WTD)
to scrapie and to compare the resultant clinical signs, lesions, and molecular
profiles of PrPSc to those of chronic wasting disease (CWD). We inoculated WTD
intracranially (IC; n = 5) and by a natural route of exposure (concurrent oral
and intranasal (IN); n = 5) with a US scrapie isolate. All deer were inoculated
with a 10% (wt/vol) brain homogenate from sheep with scrapie (1ml IC, 1 ml IN,
30 ml oral). All deer inoculated by the intracranial route had evidence of PrPSc
accumulation. PrPSc was detected in lymphoid tissues as early as 7
months-post-inoculation (PI) and a single deer that was necropsied at 15.6
months had widespread distribution of PrPSc highlighting that PrPSc is widely
distributed in the CNS and lymphoid tissues prior to the onset of clinical
signs. IC inoculated deer necropsied after 20 months PI (3/5) had clinical
signs, spongiform encephalopathy, and widespread distribution of PrPSc in neural
and lymphoid tissues. The results of this study suggest that there are many
similarities in the manifestation of CWD and scrapie in WTD after IC inoculation
including early and widespread presence of PrPSc in lymphoid tissues, clinical
signs of depression and weight loss progressing to wasting, and an incubation
time of 21-23 months. Moreover, western blots (WB) done on brain material from
the obex region have a molecular profile similar to CWD and distinct from
tissues of the cerebrum or the scrapie inoculum. However, results of microscopic
and IHC examination indicate that there are differences between the lesions
expected in CWD and those that occur in deer with scrapie: amyloid plaques were
not noted in any sections of brain examined from these deer and the pattern of
immunoreactivity by IHC was diffuse rather than plaque-like. After a natural
route of exposure, 100% of WTD were susceptible to scrapie. Deer developed
clinical signs of wasting and mental depression and were necropsied from 28 to
33 months PI. Tissues from these deer were positive for PrPSc by IHC and WB.
Similar to IC inoculated deer, samples from these deer exhibited two different
molecular profiles: samples from obex resembled CWD whereas those from cerebrum
were similar to the original scrapie inoculum. On further examination by WB
using a panel of antibodies, the tissues from deer with scrapie exhibit
properties differing from tissues either from sheep with scrapie or WTD with
CWD. Samples from WTD with CWD or sheep with scrapie are strongly immunoreactive
when probed with mAb P4, however, samples from WTD with scrapie are only weakly
immunoreactive. In contrast, when probed with mAb’s 6H4 or SAF 84, samples from
sheep with scrapie and WTD with CWD are weakly immunoreactive and samples from
WTD with scrapie are strongly positive. This work demonstrates that WTD are
highly susceptible to sheep scrapie, but on first passage, scrapie in WTD is
differentiable from CWD.
2011
*** After a natural route of exposure, 100% of white-tailed deer were
susceptible to scrapie.
Scrapie in Deer: Comparisons and Contrasts to Chronic Wasting Disease (CWD)
Justin J. Greenlee of the Virus and Prion Diseases Research Unit, National
Animal Disease Center, ARS, USDA, Ames, IA provided a presentation on scrapie
and CWD in inoculated deer. Interspecies transmission studies afford the
opportunity to better understand the potential host range and origins of prion
diseases. We inoculated white-tailed deer intracranially (IC) and by a natural
route of exposure (concurrent oral and intranasal inoculation) with a US scrapie
isolate. All deer inoculated by the intracranial route had evidence of PrPSc
accumulation and those necropsied after 20 months post-inoculation (PI) (3/5)
had clinical signs, spongiform encephalopathy, and widespread distribution of
PrPSc in neural and lymphoid tissues. A single deer that was necropsied at 15.6
months PI did not have clinical signs, but had widespread distribution of PrPSc.
This highlights the facts that 1) prior to the onset of clinical signs PrPSc is
widely distributed in the CNS and lymphoid tissues and 2) currently used
diagnostic methods are sufficient to detect PrPSc prior to the onset of clinical
signs. The results of this study suggest that there are many similarities in the
manifestation of CWD and scrapie in white-tailed deer after IC inoculation
including early and widespread presence of PrPSc in lymphoid tissues, clinical
signs of depression and weight loss progressing to wasting, and an incubation
time of 21-23 months. Moreover, western blots (WB) done on brain material from
the obex region have a molecular profile consistent with CWD and distinct from
tissues of the cerebrum or the scrapie inoculum. However, results of microscopic
and IHC examination indicate that there are differences between the lesions
expected in CWD and those that occur in deer with scrapie: amyloid plaques were
not noted in any sections of brain examined from these deer and the pattern of
immunoreactivity by IHC was diffuse rather than plaque-like. After a natural
route of exposure, 100% of white-tailed deer were susceptible to scrapie. Deer
developed clinical signs of wasting and mental depression and were necropsied
from 28 to 33 months PI. Tissues from these deer were positive for scrapie by
IHC and WB. Tissues with PrPSc immunoreactivity included brain, tonsil,
retropharyngeal and mesenteric lymph nodes, hemal node, Peyer’s patches, and
spleen. While two WB patterns have been detected in brain regions of deer
inoculated by the natural route, unlike the IC inoculated deer, the pattern
similar to the scrapie inoculum predominates.
Committee Business:
The Committee discussed and approved three resolutions regarding CWD. They
can be found in the report of the Reswolutions Committee. Essentially the
resolutions urged USDA-APHIS-VS to:
Continue to provide funding for CWD testing of captive cervids
Finalize and publish the national CWD rule for Herd Certification and
Interstate Movement
Evaluate live animal test, including rectal mucosal biopsy, for CWD in
cervids
2011 Annual Report
Research Project: TRANSMISSION, DIFFERENTIATION, AND PATHOBIOLOGY OF
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES Location: Virus and Prion Research
Unit
2011 Annual Report
In Objective 1, Assess cross-species transmissibility of transmissible
spongiform encephalopathies (TSEs) in livestock and wildlife, numerous
experiments assessing the susceptibility of various TSEs in different host
species were conducted. Most notable is deer inoculated with scrapie, which
exhibits similarities to chronic wasting disease (CWD) in deer suggestive of
sheep scrapie as an origin of CWD.
snip...
4.Accomplishments 1. Deer inoculated with domestic isolates of sheep
scrapie. Scrapie-affected deer exhibit 2 different patterns of disease
associated prion protein. In some regions of the brain the pattern is much like
that observed for scrapie, while in others it is more like chronic wasting
disease (CWD), the transmissible spongiform encephalopathy typically associated
with deer. This work conducted by ARS scientists at the National Animal Disease
Center, Ames, IA suggests that an interspecies transmission of sheep scrapie to
deer may have been the origin of CWD. This is important for husbandry practices
with both captive deer, elk and sheep for farmers and ranchers attempting to
keep their herds and flocks free of CWD and scrapie.
White-tailed Deer are Susceptible to Scrapie by Natural Route of Infection
Jodi D. Smith, Justin J. Greenlee, and Robert A. Kunkle; Virus and Prion
Research Unit, National Animal Disease Center, USDA-ARS
Interspecies transmission studies afford the opportunity to better
understand the potential host range and origins of prion diseases. Previous
experiments demonstrated that white-tailed deer are susceptible to sheep-derived
scrapie by intracranial inoculation. The purpose of this study was to determine
susceptibility of white-tailed deer to scrapie after a natural route of
exposure. Deer (n=5) were inoculated by concurrent oral (30 ml) and intranasal
(1 ml) instillation of a 10% (wt/vol) brain homogenate derived from a sheep
clinically affected with scrapie. Non-inoculated deer were maintained as
negative controls. All deer were observed daily for clinical signs. Deer were
euthanized and necropsied when neurologic disease was evident, and tissues were
examined for abnormal prion protein (PrPSc) by immunohistochemistry (IHC) and
western blot (WB). One animal was euthanized 15 months post-inoculation (MPI)
due to an injury. At that time, examination of obex and lymphoid tissues by IHC
was positive, but WB of obex and colliculus were negative. Remaining deer
developed clinical signs of wasting and mental depression and were necropsied
from 28 to 33 MPI. Tissues from these deer were positive for scrapie by IHC and
WB. Tissues with PrPSc immunoreactivity included brain, tonsil, retropharyngeal
and mesenteric lymph nodes, hemal node, Peyer’s patches, and spleen. This work
demonstrates for the first time that white-tailed deer are susceptible to sheep
scrapie by potential natural routes of inoculation. In-depth analysis of tissues
will be done to determine similarities between scrapie in deer after
intracranial and oral/intranasal inoculation and chronic wasting disease
resulting from similar routes of inoculation.
see full text ;
Wednesday, January 02, 2013
Iowa Third Deer Positive CWD at Davis County Hunting Preserve Captive
Shooting Pen
Friday, December 14, 2012
IOWA Second Deer Positive for CWD at Davis County Hunting Preserve Captive
Shooting Pen
Friday, September 21, 2012
Chronic Wasting Disease CWD raises concerns about deer farms in Iowa
Tuesday, September 11, 2012
Agreement Reached with Owner to De-Populate CWD Deer at Davis County
Hunting Preserve Iowa
Wednesday, September 05, 2012
Additional Facility in Pottawatamie County Iowa Under Quarantine for CWD
after 5 deer test positive
Friday, July 20, 2012
CWD found for first time in Iowa at hunting preserve
SOME OLD HISTORY ON CWD AND GAME FARMS ;
see more here;
CWD policies in various states SCWDS BRIEFS April 1998 Issue State Fish
& Game Departments: all 50 states
Nebraska Dept of Agriculture and Game and Parks
On April 9, 1998, chronic wasting disease (CWD) was diagnosed in a captive
elk in Nebraska.� This discovery follows the confirmation of CWD in two captive
elk herds in South Dakota earlier this year.� The Nebraska elk was a 4 1/2-year
old male that was among a privately owned herd of approximately 150 elk.� The
health of the animal had deteriorated for about 2 months before it died.�
Confirmation of CWD was made by the USDA's National Veterinary Services
Laboratories in Ames, Iowa. The case history revealed that the affected elk was
born on a farm on the Western Slope of the Rocky Mountains in Colorado, but it
was on two additional Colorado farms before it arrived in Nebraska at 2 to 2 1/2
years of age.� One of the Colorado premises was in the known CWD-endemic region
along the Eastern Slope of the Rocky Mountains in northcentral Colorado.
snip...
CWD News: Under-diagnosis in elk: 10/17 prove positive with better method
21 Jan 99 -- Utah hunter: CWD blood recall? 20 Dec 98 -- Bad news on game farm
elk CWD 12 Nov 98 --Colorado CJD tragedy and CWD concerns 11 Oct 98 -- Nevada
testing deer and elk for CWD 23 Jun 98 -- Elk CWD spreading on game farms 19 Mar
98 -- BSE Inquiry: Day 6 -- Mink and CWD misinformation 19 Mar 98 -- CWD:
spreading it around 19 Mar 98 -- CWD: failed eradication attempts 19 Mar 98 --
CWD in Estes Park: what goes on at Lexington Lane? 19 Mar 98 -- 14 facilities
where CWD has been found 19 Mar 98 -- How did CWD get started and spread? 19 Mar
98 -- Elk growers ask for surveillance in N. Dakota 19 Mar 98 -- Ban on elk
antlers in human food rejected 19 Mar 98 -- CWD in High Country News 19 Mar 98
-- CWD Web Resources 14 Feb 98 -- Colorado's dementia experiment in humans 24
Feb 98 -- Feds need to take control over Colorado CWD 14 Feb 98 -- Surveillance
for chronic wasting disease in Colorado 14 Feb 98 -- CWD by river drainage 14
Feb 98 -- Some early history of CWD 10 Jul 97 -- Chronic Wasting Disease in
Canada23 Jul 98 -- Saskatchewan elk disease waning? 14 Feb 98 -- More chronic
wasting disease news: 1, 2 14 Feb 98 -- Welcome to Stetsonville 07 Feb 98 --
Deer in three Wyoming counties infected with chronic wasting disease 07 Feb 98
-- Chronic wasting disease: deer-to-cattle shown 07 Feb 98 -- Worry over CWD
hazards 05 Feb 98 -- Canada reports CWD in mule deer on game farms 07 Feb 98 --
Dr. Steven Dealler on CWD risks 27 Jan 98 -- Concerned rancher writes in about
deer feeding habits 03 Feb 98 -- To eat or not to eat is the hunter's question
01 Mar 97 -- CWD and hunters square off in Colorado 01 Apr 97 -- CWD: lab
progress is slow 01 Mar 97 -- Mystery of CWD in US deer, elk explained? Chronic
wasting disease update
snip...see ;
Thursday, February 09, 2012
50 GAME FARMS IN USA INFECTED WITH CHRONIC WASTING DISEASE
The chances of a person or domestic animal contracting CWD are “extremely
remote,” Richards said. The possibility can’t be ruled out, however. “One could
look at it like a game of chance,” he explained. “The odds (of infection)
increase over time because of repeated exposure. That’s one of the downsides of
having CWD in free-ranging herds: We’ve got this infectious agent out there that
we can never say never to in terms of (infecting) people and domestic
livestock.”
*** The potential impact of prion diseases on human health was greatly
magnified by the recognition that interspecies transfer of BSE to humans by beef
ingestion resulted in vCJD. While changes in animal feed constituents and
slaughter practices appear to have curtailed vCJD, there is concern that CWD of
free-ranging deer and elk in the U.S. might also cross the species barrier.
Thus, consuming venison could be a source of human prion disease. Whether BSE
and CWD represent interspecies scrapie transfer or are newly arisen prion
diseases is unknown. Therefore, the possibility of transmission of prion disease
through other food animals cannot be ruled out. There is evidence that vCJD can
be transmitted through blood transfusion. There is likely a pool of unknown size
of asymptomatic individuals infected with vCJD, and there may be asymptomatic
individuals infected with the CWD equivalent. These circumstances represent a
potential threat to blood, blood products, and plasma supplies.
Friday, November 09, 2012
*** Chronic Wasting Disease CWD in cervidae and transmission to other
species
Sunday, November 11, 2012
*** Susceptibilities of Nonhuman Primates to Chronic Wasting Disease
November 2012
Friday, December 14, 2012
Susceptibility Chronic Wasting Disease (CWD) in wild cervids to Humans 2005
- December 14, 2012
TSS
posted by Terry S. Singeltary Sr. at
9:54 AM
0 Comments:
Post a Comment
Subscribe to Post Comments [Atom]
<< Home