Pennsylvania Monitoring the Growing Threat of Chronic Wasting Disease CWD TSE Prion
Monitoring the Growing Threat of Chronic Wasting Disease
DMA 1
Chronic Wasting Disease (CWD) poses a serious threat to Pennsylvania’s
white-tailed deer population and to the future of deer hunting and wildlife
management.
CWD is an always-fatal prion disease affecting the brain and central
nervous system of white-tailed deer and elk. It was first found on a captive
deer farm in Adams County in 2012 (DMA 1) and on two captive deer farms in
Jefferson County in 2014 (DMA 3). Since 2012, seventeen free-ranging wild deer
from Bedford, Blair, and Fulton counties have tested positive for CWD (DMA 2).
Seven of which were in the past year.
The Pennsylvania Game Commission has issued Executive Orders establishing
boundaries and regulations for these three Disease Management Areas (DMAs)
including a ban on movement of highrisk deer parts from these areas as well as
an enhanced monitoring program. The Game Commission’s monitoring program
continues to document new cases in wild deer. These new cases have resulted in
increased concern and further expansion of DMA 2.
As a result of new cases, the Game Commission enhanced its monitoring
efforts during 2015. Originally designed to assess distribution and occurrence
of the disease, enhanced sampling seeks to assess prevalence within DMAs while
continuing statewide surveillance. Sample collection efforts from deer that were
hunter-harvested, road-killed, crop-kills, escapes, and clinical suspects
resulted in 5,619 deer samples. These included 616 from DMA 1, 1,593 from DMA 2,
363 from DMA 3 and 47 clinically suspect deer, exhibiting symptoms consistent
with CWD infection. Final testing results are expected in March 2016. The Game
Commission is currently consulting with wildlife professionals across the
country who are struggling to find solutions to this disease problem.
Saturday, November 07, 2015
PENNSYLVANIA CHRONIC WASTING DISEASE CWD TSE PRION RULES EXPAND
Saturday, November 07, 2015
Pennsylvania 2015 September Minutes CWD Urine Scents
Sunday, October 18, 2015
Pennsylvania Game Commission Law and Law Makers CWD TSE PRION Bans
Singeltary 2002 from speaking A smelly situation UPDATED 2015
Tuesday, May 05, 2015
Pennsylvania CWD DETECTED IN SIX MORE FREE-RANGING DEER Disease Management
Area 2 again expanded due to new cases Release #030-15
**********2014 PENNSYLVANIA CWD**********
Tuesday, October 21, 2014
Pennsylvania Department of Agriculture Tenth Pennsylvania Captive Deer
Tests Positive for Chronic Wasting Disease CWD TSE PRION DISEASE
Sunday, July 13, 2014
Louisiana deer mystery unleashes litigation 6 does still missing from CWD
index herd in Pennsylvania Great Escape
Saturday, June 29, 2013
PENNSYLVANIA CAPTIVE CWD INDEX HERD MATE YELLOW *47 STILL RUNNING LOOSE IN
INDIANA, YELLOW NUMBER 2 STILL MISSING, AND OTHERS ON THE RUN STILL IN LOUISIANA
Tuesday, June 11, 2013
*** CWD GONE WILD, More cervid escapees from more shooting pens on the
loose in Pennsylvania
Tuesday, May 28, 2013
Chronic Wasting Disease CWD quarantine Louisiana via CWD index herd
Pennsylvania Update May 28, 2013
*** 6 doe from Pennsylvania CWD index herd still on the loose in Louisiana,
quarantine began on October 18, 2012, still ongoing, Lake Charles premises.
Sunday, January 06, 2013
USDA TO PGC ONCE CAPTIVES ESCAPE
*** "it‘s no longer its business.”
”The occurrence of CWD must be viewed against the contest of the locations
in which it occurred. It was an incidental and unwelcome complication of the
respective wildlife research programmes. Despite it’s subsequent recognition as
a new disease of cervids, therefore justifying direct investigation, no specific
research funding was forthcoming. The USDA veiwed it as a wildlife problem and
consequently not their province!” page 26.
Wednesday, November 14, 2012
PENNSYLVANIA 2012 THE GREAT ESCAPE OF CWD INVESTIGATION MOVES INTO
LOUISIANA and INDIANA
Tuesday, October 23, 2012
PA Captive deer from CWD-positive farm roaming free
Thursday, October 11, 2012
Pennsylvania Confirms First Case CWD Adams County Captive Deer Tests
Positive
Wednesday, February 11, 2015
World Class Whitetails quarantined CWD deer Daniel M. Yoder charged with
two counts of tampering with evidence
Tuesday, February 23, 2016
ARKANSAS Detects First Chronic Wasting Disease CWD in a wild elk
??? One of the subjects confessed to taking a fourth deer in Texas, which
was wasted and dumped in Arkansas. ???
Wrong State of Mind
A Bowie County game warden received a call from Arkansas Game and Fish
officers in reference to a truck they had stopped that was traveling east on
Interstate 30 from Texas. The vehicle contained 10 whitetail deer, a bobcat and
a turkey breast that had all been harvested in Central Texas. It is illegal to
transport a deer with bones from a chronic wasting disease state into the state
of Arkansas. Since the wildlife officers in Arkansas were not entirely familiar
with Texas laws, they requested the Bowie County warden to inspect the subject’s
game for any Texas violations. The warden inspected the deer at the Arkansas
Game and Fish district office and wrote several citations for tagging
proof-of-sex violations. The state of Arkansas filed several cases for
transporting deer with bone still attached, seized all of the animals and parts
for their violations, and tested the deer for chronic wasting disease.
Don’t Mess With Texas... or Arkansas
A Gregg County game warden responded to a Longview Animal Control call
regarding a decaying doe hanging in a resident’s tree. When the warden located
the deer, he also discovered an additional untagged doe behind the property and
an untagged nine-point buck. Two of the four individuals interviewed claimed
they harvested the two deer in Arkansas. One of the subjects confessed to taking
a fourth deer in Texas, which was wasted and dumped in Arkansas. When questioned
about the discrepancy between their harvest dates versus the date printed on
their Arkansas hunting licenses, two of the subjects acknowledged hunting
without a license. The warden then contacted Arkansas Game and Fish Commission
wildlife officers who advised that they were pursuing more than $2,500 in
charges. They also said that two of the men face one year suspensions, while
another would receive a lifetime hunting license suspension in Arkansas. Civil
restitution and multiple charges were filed, including no hunting license;
hunting during closed season; failure to keep game in edible condition; untagged
deer; and no harvest log. Investigation is ongoing and cases pending.
Tuesday, February 23, 2016
Parks and Wildlife begins reducing deer population at Texas Mountain Ranch
Chronic Wasting Disease CWD TSE Prion Update
*** I kindly would like to comment on a few statements from the TPWD et al
;
http://chronic-wasting-disease.blogspot.com/2016/02/parks-and-wildlife-begins-reducing-deer.html
Wednesday, February 10, 2016
*** Wisconsin Two deer that escaped farm had chronic wasting disease CWD
***
Friday, February 05, 2016
*** Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION
Detections in Farmed Cervids and Wild ***
Saturday, February 6, 2016
*** Secretary's Advisory Committee on Animal Health; Meeting [Docket No.
APHIS-2016-0007] Singeltary Submission ***
*** PRION 2015 CONFERENCE FT. COLLINS CWD TSE PRION RISK FACTORS TO HUMANS
***
*** LATE-BREAKING ABSTRACTS PRION 2015 CONFERENCE ***
O18
Zoonotic Potential of CWD Prions
Liuting Qing1, Ignazio Cali1,2, Jue Yuan1, Shenghai Huang3, Diane Kofskey1,
Pierluigi Gambetti1, Wenquan Zou1, Qingzhong Kong1 1Case Western Reserve
University, Cleveland, Ohio, USA, 2Second University of Naples, Naples, Italy,
3Encore Health Resources, Houston, Texas, USA
*** These results indicate that the CWD prion has the potential to infect
human CNS and peripheral lymphoid tissues and that there might be asymptomatic
human carriers of CWD infection.
==================
***These results indicate that the CWD prion has the potential to infect
human CNS and peripheral lymphoid tissues and that there might be asymptomatic
human carriers of CWD infection.***
==================
P.105: RT-QuIC models trans-species prion transmission
Kristen Davenport, Davin Henderson, Candace Mathiason, and Edward Hoover
Prion Research Center; Colorado State University; Fort Collins, CO USA
Conversely, FSE maintained sufficient BSE characteristics to more
efficiently convert bovine rPrP than feline rPrP. Additionally, human rPrP was
competent for conversion by CWD and fCWD.
***This insinuates that, at the level of protein:protein interactions, the
barrier preventing transmission of CWD to humans is less robust than previously
estimated.
================
***This insinuates that, at the level of protein:protein interactions, the
barrier preventing transmission of CWD to humans is less robust than previously
estimated.***
================
*** PRICE OF CWD TSE PRION POKER GOES UP 2014 ***
Transmissible Spongiform Encephalopathy TSE PRION update January 2, 2014
*** chronic wasting disease, there was no absolute barrier to conversion of
the human prion protein.
*** Furthermore, the form of human PrPres produced in this in vitro assay
when seeded with CWD, resembles that found in the most common human prion
disease, namely sCJD of the MM1 subtype.
Envt.07:
Pathological Prion Protein (PrPTSE) in Skeletal Muscles of Farmed and Free
Ranging White-Tailed Deer Infected with Chronic Wasting Disease
***The presence and seeding activity of PrPTSE in skeletal muscle from
CWD-infected cervids suggests prevention of such tissue in the human diet as a
precautionary measure for food safety, pending on further clarification of
whether CWD may be transmissible to humans.
*** These results would seem to suggest that CWD does indeed have zoonotic
potential, at least as judged by the compatibility of CWD prions and their human
PrPC target. Furthermore, extrapolation from this simple in vitro assay suggests
that if zoonotic CWD occurred, it would most likely effect those of the PRNP
codon 129-MM genotype and that the PrPres type would be similar to that found in
the most common subtype of sCJD (MM1).***
*** The potential impact of prion diseases on human health was greatly
magnified by the recognition that interspecies transfer of BSE to humans by beef
ingestion resulted in vCJD. While changes in animal feed constituents and
slaughter practices appear to have curtailed vCJD, there is concern that CWD of
free-ranging deer and elk in the U.S. might also cross the species barrier.
Thus, consuming venison could be a source of human prion disease. Whether BSE
and CWD represent interspecies scrapie transfer or are newly arisen prion
diseases is unknown. Therefore, the possibility of transmission of prion disease
through other food animals cannot be ruled out. There is evidence that vCJD can
be transmitted through blood transfusion. There is likely a pool of unknown size
of asymptomatic individuals infected with vCJD, and there may be asymptomatic
individuals infected with the CWD equivalent. These circumstances represent a
potential threat to blood, blood products, and plasma supplies.
*** The association between venison eating and risk of CJD shows similar
pattern, with regular venison eating associated with a 9 FOLD INCREASE IN RISK
OF CJD (p = 0.04).
see links below, on further down in this posting to the BSE Inquiry and the
CJD study back in 1994...tss
CJD9/10022
October 1994
Mr R.N. Elmhirst Chairman British Deer Farmers Association Holly Lodge
Spencers Lane BerksWell Coventry CV7 7BZ
Dear Mr Elmhirst,
CREUTZFELDT-JAKOB DISEASE (CJD) SURVEILLANCE UNIT REPORT
Thank you for your recent letter concerning the publication of the third
annual report from the CJD Surveillance Unit. I am sorry that you are
dissatisfied with the way in which this report was published.
http://web.archive.org/web/20030511010117/http://www.bseinquiry.gov.uk/files/yb/1994/10/00003001.pdf
O.05: Transmission of prions to primates after extended silent incubation
periods: Implications for BSE and scrapie risk assessment in human populations
Emmanuel Comoy, Jacqueline Mikol, Val erie Durand, Sophie Luccantoni,
Evelyne Correia, Nathalie Lescoutra, Capucine Dehen, and Jean-Philippe Deslys
Atomic Energy Commission; Fontenay-aux-Roses, France
Prion diseases (PD) are the unique neurodegenerative proteinopathies
reputed to be transmissible under field conditions since decades. The
transmission of Bovine Spongiform Encephalopathy (BSE) to humans evidenced that
an animal PD might be zoonotic under appropriate conditions. Contrarily, in the
absence of obvious (epidemiological or experimental) elements supporting a
transmission or genetic predispositions, PD, like the other proteinopathies, are
reputed to occur spontaneously (atpical animal prion strains, sporadic CJD
summing 80% of human prion cases). Non-human primate models provided the first
evidences supporting the transmissibiity of human prion strains and the zoonotic
potential of BSE. Among them, cynomolgus macaques brought major information for
BSE risk assessment for human health (Chen, 2014), according to their
phylogenetic proximity to humans and extended lifetime. We used this model to
assess the zoonotic potential of other animal PD from bovine, ovine and cervid
origins even after very long silent incubation periods. *** We recently observed
the direct transmission of a natural classical scrapie isolate to macaque after
a 10-year silent incubation period, ***with features similar to some reported
for human cases of sporadic CJD, albeit requiring fourfold longe incubation than
BSE. Scrapie, as recently evoked in humanized mice (Cassard, 2014), ***is the
third potentially zoonotic PD (with BSE and L-type BSE), ***thus questioning the
origin of human sporadic cases. We will present an updated panorama of our
different transmission studies and discuss the implications of such extended
incubation periods on risk assessment of animal PD for human health.
===============
***thus questioning the origin of human sporadic cases...TSS
===============
Tuesday, February 23, 2016
ARKANSAS Detects First Chronic Wasting Disease CWD in a wild elk
??? One of the subjects confessed to taking a fourth deer in Texas, which
was wasted and dumped in Arkansas. ???
Wrong State of Mind
A Bowie County game warden received a call from Arkansas Game and Fish
officers in reference to a truck they had stopped that was traveling east on
Interstate 30 from Texas. The vehicle contained 10 whitetail deer, a bobcat and
a turkey breast that had all been harvested in Central Texas. It is illegal to
transport a deer with bones from a chronic wasting disease state into the state
of Arkansas. Since the wildlife officers in Arkansas were not entirely familiar
with Texas laws, they requested the Bowie County warden to inspect the subject’s
game for any Texas violations. The warden inspected the deer at the Arkansas
Game and Fish district office and wrote several citations for tagging
proof-of-sex violations. The state of Arkansas filed several cases for
transporting deer with bone still attached, seized all of the animals and parts
for their violations, and tested the deer for chronic wasting disease.
Don’t Mess With Texas... or Arkansas
A Gregg County game warden responded to a Longview Animal Control call
regarding a decaying doe hanging in a resident’s tree. When the warden located
the deer, he also discovered an additional untagged doe behind the property and
an untagged nine-point buck. Two of the four individuals interviewed claimed
they harvested the two deer in Arkansas. One of the subjects confessed to taking
a fourth deer in Texas, which was wasted and dumped in Arkansas. When questioned
about the discrepancy between their harvest dates versus the date printed on
their Arkansas hunting licenses, two of the subjects acknowledged hunting
without a license. The warden then contacted Arkansas Game and Fish Commission
wildlife officers who advised that they were pursuing more than $2,500 in
charges. They also said that two of the men face one year suspensions, while
another would receive a lifetime hunting license suspension in Arkansas. Civil
restitution and multiple charges were filed, including no hunting license;
hunting during closed season; failure to keep game in edible condition; untagged
deer; and no harvest log. Investigation is ongoing and cases pending.
Tuesday, February 23, 2016
Parks and Wildlife begins reducing deer population at Texas Mountain Ranch
Chronic Wasting Disease CWD TSE Prion Update
*** I kindly would like to comment on a few statements from the TPWD et al
;
http://chronic-wasting-disease.blogspot.com/2016/02/parks-and-wildlife-begins-reducing-deer.html
Wednesday, February 10, 2016
*** Wisconsin Two deer that escaped farm had chronic wasting disease CWD
***
Friday, February 05, 2016
*** Report of the Committee on Wildlife Diseases FY2015 CWD TSE PRION
Detections in Farmed Cervids and Wild ***
Saturday, February 6, 2016
*** Secretary's Advisory Committee on Animal Health; Meeting [Docket No.
APHIS-2016-0007] Singeltary Submission ***
Terry S. Singeltary Sr.
posted by Terry S. Singeltary Sr. at
5:21 PM
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