Current CWD Status WHHCC Meeting – 5-6 February 2013
Current CWD Status 2013
•Wild cervids: CWD has been detected in 17 states: CO, IL, KS, MD, MN, MO,
ND, NE, NY, NM, SD, TX, UT, VA, WI, WV, WY
•Farmed cervid herds: CWD has been detected in 60 farmed cervid herds (40
elk herds, 19 WTD herds,1 red deer herd) in 13 states: CO, KS, IA, MI, MN, MO,
MT, NE, NY, OK, PA, SD, WI
•In 2012: farmed red deer (MN); farmed elk (CO); farmed WTD (IA, PA) wild
WTD (KS, MO, WI); wild mule deer (TX)
•14 positive farmed herds remain
7 Elk herds (CO); 3 Elk herds (NE)
1 Red deer herd (MN)
1 WTD herds (IA), hunt facility was depopulated
1 WTD herd (PA) was depopulated
Saturday, October 19, 2013
ACA Council Meets to Endorse Several Proposed USAHA Resolutions (CWD TSE
PRION DISEASE)
Wednesday, October 16, 2013
Pennsylvania Adjusts CWD Rules
Tuesday, October 15, 2013
Indiana State to appeal high-fence deer hunting ruling
October 11, 2013
Protecting Missouri's White-Tailed Deer
fill out the questionnaire ;
Thursday, October 03, 2013
TAHC ADOPTS CWD RULE THAT the amendments remove the requirement for a
specific fence height for captives
Texas Animal Health Commission (TAHC)
ANNOUNCEMENT
October 3, 2013
Thursday, June 13, 2013
WISCONSIN DEER FARMING Chronic Wasting Disease CWD DATCP
Saturday, February 04, 2012
Wisconsin 16 MONTH age limit on testing dead deer Game Farm CWD
Testing Protocol Needs To Be Revised
how many states have
$465,000., and can quarantine and purchase there from, each cwd said infected
farm, but how many states can afford this for all the cwd infected cervid game
ranch type farms ???
Tuesday, December 20, 2011
CHRONIC WASTING DISEASE CWD WISCONSIN
Almond Deer (Buckhorn Flats) Farm Update DECEMBER 2011
The CWD infection rate was nearly 80%,
the highest ever in a North American captive herd.
RECOMMENDATION: That the Board approve
the purchase of 80 acres of land for $465,000 for the Statewide Wildlife Habitat
Program in Portage County and approve the restrictions on public use of the
site.
SUMMARY:
recently, a report came out in the
U.K., about risk factors from entry of CWD from the USA. I think you might find
interest there ;
Friday, December 14, 2012
DEFRA U.K. What is the risk of Chronic
Wasting Disease CWD being introduced into Great Britain? A Qualitative Risk
Assessment October 2012
snip...
In the USA, under the Food and Drug
Administration’s BSE Feed Regulation (21 CFR 589.2000) most material (exceptions
include milk, tallow, and gelatin) from deer and elk is prohibited for use in
feed for ruminant animals. With regards to feed for non-ruminant animals, under
FDA law, CWD positive deer may not be used for any animal feed or feed
ingredients. For elk and deer considered at high risk for CWD, the FDA
recommends that these animals do not enter the animal feed system. However, this
recommendation is guidance and not a requirement by law.
Animals considered at high risk for
CWD include:
1) animals from areas declared to be
endemic for CWD and/or to be CWD eradication zones and
2) deer and elk that at some time
during the 60-month period prior to slaughter were in a captive herd that
contained a CWD-positive animal.
Therefore, in the USA, materials from
cervids other than CWD positive animals may be used in animal feed and feed
ingredients for non-ruminants.
The amount of animal PAP that is of
deer and/or elk origin imported from the USA to GB can not be determined,
however, as it is not specified in TRACES. It may constitute a small percentage
of the 8412 kilos of non-fish origin processed animal proteins that were
imported from US into GB in 2011.
Overall, therefore, it is considered
there is a __greater than negligible risk___ that (nonruminant) animal feed and
pet food containing deer and/or elk protein is imported into GB.
There is uncertainty associated with
this estimate given the lack of data on the amount of deer and/or elk protein
possibly being imported in these products.
snip...
36% in 2007 (Almberg et al., 2011). In
such areas, population declines of deer of up to 30 to 50% have been observed
(Almberg et al., 2011). In areas of Colorado, the prevalence can be as high as
30% (EFSA, 2011). The clinical signs of CWD in affected adults are weight loss
and behavioural changes that can span weeks or months (Williams, 2005). In
addition, signs might include excessive salivation, behavioural alterations
including a fixed stare and changes in interaction with other animals in the
herd, and an altered stance (Williams, 2005). These signs are indistinguishable
from cervids experimentally infected with bovine spongiform encephalopathy
(BSE). Given this, if CWD was to be introduced into countries with BSE such as
GB, for example, infected deer populations would need to be tested to
differentiate if they were infected with CWD or BSE to minimise the risk of BSE
entering the human food-chain via affected venison.
snip...
The rate of transmission of CWD has
been reported to be as high as 30% and can approach 100% among captive animals
in endemic areas (Safar et al., 2008).
snip...
In summary, in endemic areas, there is
a medium probability that the soil and surrounding environment is contaminated
with CWD prions and in a bioavailable form. In rural areas where CWD has not
been reported and deer are present, there is a greater than negligible risk the
soil is contaminated with CWD prion.
snip...
In summary, given the volume of
tourists, hunters and servicemen moving between GB and North America, the
probability of at least one person travelling to/from a CWD affected area and,
in doing so, contaminating their clothing, footwear and/or equipment prior to
arriving in GB is greater than negligible. For deer hunters, specifically, the
risk is likely to be greater given the increased contact with deer and their
environment. However, there is significant uncertainty associated with these
estimates.
snip...
Therefore, it is considered that
farmed and park deer may have a higher probability of exposure to CWD
transferred to the environment than wild deer given the restricted habitat range
and higher frequency of contact with tourists and returning GB residents.
snip...
SNIP...SEE ;
Friday, December 14, 2012
DEFRA U.K. What is the risk of Chronic
Wasting Disease CWD being introduced into Great Britain? A Qualitative Risk
Assessment October 2012
Wednesday, September 25, 2013
Inspections, Compliance, Enforcement,
and Criminal Investigations BSE TSE PRION 2013
DOCKET-- 03D-0186 -- FDA Issues Draft
Guidance on Use of Material From Deer and Elk in Animal Feed;
Availability
Date: Fri, 16 May 2003 11:47:37
–0500
EMC 1 Terry S. Singeltary Sr. Vol #:
1
PLEASE SEE FULL TEXT SUBMISSION
;
PRION2013 CONGRESSIONAL ABSTRACTS CWD
Thursday, August 08, 2013
Characterization of the first case of naturally occurring chronic wasting
disease in a captive red deer (Cervus elaphus) in North America
Wednesday, September 25, 2013
USDA Officials: CWD Standards Going to Public Comment Soon
Wednesday, September 04, 2013
***cwd - cervid captive livestock escapes, loose and on the run in the
wild...
Sunday, September 01, 2013
hunting over gut piles and CWD TSE prion disease
Monday, October 07, 2013
The importance of localized culling in stabilizing chronic wasting disease
prevalence in white-tailed deer populations
Thursday, October 10, 2013
CJD REPORT 1994 increased risk for consumption of veal and venison and lamb
Uptake of Prions into Plants
Prion2013
Friday, August 09, 2013
***CWD TSE prion, plants, vegetables, and the potential for environmental
contamination
PRION2013 CONGRESSIONAL ABSTRACTS CWD
Sunday, August 25, 2013
HD.13: CWD infection in the spleen of humanized transgenic mice
Liuting Qing and Qingzhong Kong
Case Western Reserve University; Cleveland, OH USA
Chronic wasting disease (CWD) is a widespread prion disease in free-ranging
and captive cervid species in North America, and there is evidence suggesting
the existence of multiple CWD strains. The susceptibility of human CNS and
peripheral organs to the various CWD prion strains remains largely unclear.
Current literature suggests that the classical CWD strain is unlikely to infect
human brain, but the potential for peripheral infection by CWD in humans is
unknown. We detected protease-resistant PrpSc in the spleens of a few humanized
transgenic mice that were intracerebrally inoculated with natural CWD isolates,
but PrpSc was not detected in the brains of any of the CWD-inoculated mice. Our
ongoing bioassays in humanized Tg mice indicate that intracerebral challenge
with such PrpSc-positive humanized mouse spleen already led to prion disease in
most animals.
***These results indicate that the CWD prion may have the potential to
infect human peripheral lymphoid tissues.
Oral.15: Molecular barriers to zoonotic prion transmission: Comparison of
the ability of sheep, cattle and deer prion disease isolates to convert normal
human prion protein to its pathological isoform in a cell-free system
Marcelo A.Barria,1 Aru Balachandran,2 Masanori Morita,3 Tetsuyuki
Kitamoto,4 Rona Barron,5 Jean Manson,5 Richard Kniqht,1 James W. lronside1 and
Mark W. Head1
1National CJD Research and Surveillance Unit; Centre for Clinical Brain
Sciences; School of Clinical Sciences; The University of Edinburgh; Edinburgh,
UK; 2National and OIE Reference Laboratory for Scrapie and CWD; Canadian Food
Inspection Agency; Ottawa Laboratory; Fallowfield. ON Canada; 3Infectious
Pathogen Research Section; Central Research Laboratory; Japan Blood Products
Organization; Kobe, Japan; 4Department of Neurological Science; Tohoku
University Graduate School of Medicine; Sendai. Japan; 5Neurobiology Division;
The Roslin Institute and R(D)SVS; University of Edinburgh; Easter Bush;
Midlothian; Edinburgh, UK
Background. Bovine spongiform encephalopathy (BSE) is a known zoonotic
prion disease, resulting in variant Creurzfeldt- Jakob disease (vCJD) in humans.
In contrast, classical scrapie in sheep is thought to offer little or no danger
to human health. However, a widening range of prion diseases have been
recognized in cattle, sheep and deer. The risks posed by individual animal prion
diseases to human health cannot be determined a priori and are difficult to
assess empirically. The fundamemal event in prion disease pathogenesis is
thought to be the seeded conversion of normal prion protein (PrPC) to its
pathological isoform (PrPSc). Here we report the use of a rapid molecular
conversion assay to test whether brain specimens from different animal prion
diseases are capable of seeding the conversion of human PrPC ro PrPSc.
Material and Methods. Classical BSE (C-type BSE), H-type BSE, L-type BSE,
classical scrapie, atypical scrapie, chronic wasting disease and vCJD brain
homogenates were tested for their ability to seed conversion of human PrPC to
PrPSc in protein misfolding cyclic amplification (PMCA) reactions. Newly formed
human PrPSc was detected by protease digestion and western blotting using the
antibody 3F4.
Results. C-type BSE and vCJD were found to efficiently convert PrPC to
PrPSc. Scrapie failed to convert human PrPC to PrPSc. Of the other animal prion
diseases tested only chronic wasting disease appeared to have the capability ro
convert human PrPC to PrPSc. The results were consistent whether the human PrPC
came from human brain, humanised transgenic mouse brain or from cultured human
cells and the effect was more pronounced for PrPC with methionine at codon 129
compared with that with valine.
Conclusion. Our results show that none of the tested animal prion disease
isolates are as efficient as C-type BSE and vCJD in converting human prion
protein in this in vitro assay.
***However, they also show that there is no absolute barrier ro conversion
of human prion protein in the case of chronic wasting disease.
PRION2013 CONGRESSIONAL ABSTRACTS CWD
Sunday, August 25, 2013
***Chronic Wasting Disease CWD risk factors, humans, domestic cats, blood,
and mother to offspring transmission
Sunday, July 21, 2013
*** As Chronic Wasting Disease CWD rises in deer herd, what about risk for
humans?
layperson...tss
posted by Terry S. Singeltary Sr. at
9:13 PM
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