Friday, February 26, 2010

Chronic wasting disease found in Missouri deer

February 25, 2010

Chronic Wasting Disease Found in Captive Deer


The Missouri Departments of Agriculture, Conservation and Health and Senior Services and the U.S. Department of Agriculture announced today that a captive white-tailed deer in Linn County, Missouri has tested positive for Chronic Wasting Disease (CWD). CWD is a neurological disease found in deer, elk and moose.

"There is no evidence that CWD poses a risk to domestic animals or humans," said State Veterinarian Dr. Taylor Woods. "We have protocols in place to quickly and effectively handle these situations."

The animal that tested positive for CWD was a white-tailed deer inspected as part of the State's CWD surveillance and testing program. Preliminary tests were conducted by the USDA National Veterinary Services Laboratory in Ames, Iowa.

Upon receiving the confirmed CWD positive, Missouri's departments of Agriculture, Conservation and Health and Senior Services initiated their CWD Contingency Plan. The plan was developed in 2002 by the Cervid Health Committee, a task force comprised of veterinarians, animal health officers and conservation officers from USDA, MDA, MDC and DHSS working together to mitigate challenges associated with CWD.

CWD is transmitted by live animal to animal contact or soil to animal contact. The disease was first recognized in 1967 in captive mule deer in the Colorado Division of Wildlife captive wildlife research facility in Fort Collins, Colorado. CWD has been documented in deer and/or elk in Colorado, Illinois, Kansas, Michigan, Minnesota, Montana, Nebraska, New Mexico, New York, Oklahoma, South Dakota, Utah, Virginia, West Virginia, Wisconsin, and the Canadian Provinces of Alberta and Saskatchewan. There has been no evidence that the disease can be transmitted to humans.

"Missouri's proactive steps to put a testing protocol in place and create a contingency plan years ago is proving beneficial. We are in a solid position to follow pre-established steps to ensure Missouri's valuable whitetail deer resource remains healthy and strong," said Jason Sumners Missouri's Deer Biologist.

For more information regarding CWD, please contact Dr. Taylor Woods at (573) 751-3377.


http://mda.mo.gov/news/2010/Chronic_Wasting_Disease_Found_in_Captive_Deer



Chronic wasting disease found in Missouri deer


Thursday, February 25, 2010 6:52 p.m. CST BY The Associated Press JEFFERSON CITY — State officials have said a captive white-tail deer in northern Linn County has tested positive for chronic wasting disease.

The disease is transmitted from animal to animal or from soil to animal, and there is no risk to domestic animals or humans, the state veterinarian said Thursday.

Chronic wasting disease is a neurological disease found in deer, elk and moose. It has been documented in 15 states and two Canadian provinces.

The farm-raised deer in Linn County had been inspected as part of Missouri's chronic wasting disease surveillance and testing program. A representative from the agriculture department said the state immediately initiated a contingency plan to limit spread of the disease among the deer population.

The state-issued news release:

JEFFERSON CITY — The Missouri Departments of Agriculture, Conservation and Health and Senior Services, and the U.S. Department of Agriculture announced today that a captive white-tailed deer in Linn County, Missouri has tested positive for Chronic Wasting Disease. CWD is a neurological disease found in deer, elk and moose.

“There is no evidence that CWD poses a risk to domestic animals or humans,” said State Veterinarian Dr. Taylor Woods. “We have protocols in place to quickly and effectively handle these situations.”

The animal that tested positive for CWD was a white-tailed deer inspected as part of the State’s CWD surveillance and testing program. Preliminary tests were conducted by the USDA National Veterinary Services Laboratory in Ames, Iowa.

Upon receiving the confirmed CWD positive, Missouri’s departments of Agriculture, Conservation and Health and Senior Services initiated their CWD Contingency Plan. The plan was developed in 2002 by the Cervid Health Committee, a task force comprised of veterinarians, animal health officers and conservation officers from USDA, MDA, MDC and DHSS working together to mitigate challenges associated with CWD.

CWD is transmitted by live animal to animal contact or soil to animal contact. The disease was first recognized in 1967 in captive mule deer in the Colorado Division of Wildlife captive wildlife research facility in Fort Collins, Colorado. CWD has been documented in deer and/or elk in Colorado, Illinois, Kansas, Michigan, Minnesota, Montana, Nebraska, New Mexico, New York, Oklahoma, South Dakota, Utah, Virginia, West Virginia, Wisconsin, and the Canadian Provinces of Alberta and Saskatchewan. There has been no evidence that the disease can be transmitted to humans.

“Missouri’s proactive steps to put a testing protocol in place and create a contingency plan years ago is proving beneficial. We are in a solid position to follow pre-established steps to ensure Missouri’s valuable whitetail deer resource remains healthy and strong,” said Jason Sumners Missouri’s Deer Biologist.


http://www.columbiamissourian.com/stories/2010/02/25/chronic-wasting-disease-found-mo-deer/





Missouri Conservationist

VOLUME 71, ISSUE 2, FEBRUARY 2010

• Keeping Missouri's deer herd free from chron­ic wasting disease continues to be a high prior­ity. In the past, the Conservation Department monitored CWD in captive deer herds. Now the Missouri Department of Agriculture will be in charge of the herds, which are not part of Missouri's wild deer population. The Conservation Department will continue to test for CWD in wild deer and work with the Department of Agriculture if CWD is detected.

• Hunters who travel from another state and are transporting harvested deer, moose or elk with the spinal column or head attached must report the carcasses' entry into Missouri to the Conservation Department within 24 hours of entering the state, and the carcass must be tak­en to a licensed meat processor or taxidermist within 72 hours of entry. Meat processors and taxidermists must dispose of the spinal cord and other parts in a properly permitted landfill.

Hunters do not need to contact the Department if they are bringing back cut and wrapped meat that has been boned out, quarters and other portions of meat with no part of the spinal column or head attached; hides or capes from which all excess tissue has been removed; antlers; antlers attached to skull plates or skulls cleaned of all muscle and brain tissue; upper canine teeth; and finished taxidermy products.

To see all the regulations on a specific conservation area and to find out what is available to do, go to www.MissouriConservation.org/2930. You can search by county, area name or region.

• Two changes have been made to the Wildlife Collector's Permit, which allow researchers to take species from the wild to study. To help keep diseases from spreading, wildlife held in captivity away from the area they were taken are not to be returned to the wild unless ap­proved ahead of time. Also, helpers who do not have their own permit must be under the direct, in-person supervision of the permit holder at all times.

http://mdc.mo.gov/documents/conmag/2010/20100201.pdf




Chronic Wasting Disease and Cervidae Regulations in North America MI Department of Natural Resources Contact: Melinda Cosgrove (cosgrovm@michigan.gov 517-336-5043) January 2010

State/Province

Missouri

Agency (with jurisdiction over captive cervids) and Contacts

Dept. of Agriculture regulates elk meeting the "livestock" definition (Contact Person for Dept. of Agriculture is Dr. Taylor Woods, DVM - Missouri State Veterinarian (573) 751-3377). Department of Conservation regulates free-ranging elk, mule deer, and white-tailed and captive cervids in hunting preserves and breeding facilities. Contact Dean Harre, dean.harre@mdc.mo.gov (573) 751-4115 ext. 3258. Missouri has a State CWD Task Force co-chaired by the Departments of Agriculture and Conservation. Participants include a broad array of stakeholders including the captive cervid industry, meat processors and conservation organizations. Change to occur - March 1, 2010 the Missouri Department of Agriculture will assume the role of regulating all herds (elk, mule deer, and white-tailed deer) that are enrolled in the State's CWD monitoring program.

Standard Regulations * (listed only if different or in addition to those listed below)

See CWD Regulations

Chronic Wasting Disease (CWD) Regulations for Captive Cervids and Wildlife

1.) Captive cervids will not be allowed to enter the state if within the last five years the animal: (A) is from an area that has been reported as a CWD endemic area; (B) has been in a CWD endemic area; (C) originates from a CWD positive herd.; 2.) All elk, elk-hybrids, red deer, sika deer, white-tailed deer, and mule deer entering Missouri from any state must have participated in a surveillance program for five consecutive years before the above mentioned animals will be allowed to enter Missouri from any state. ; 3.) Other captive cervids other than elk, elk-hybrids, red deer, sika deer, white-tailed deer and mule deer must have participated in a surveillance program recognized by the state of origin prior to entering Missouri. ; 4.) One hundred percent (100%) of all elk, elk hybrids, mule deer and whitetail deer over 12 months of age that die of any cause in a breeder operation shall be tested for CWD at a federally approved laboratory, up to an annual total of ten (10) animals in the aggregate. 5.) Except all captive white-tailed deer that enter Missouri, (imports) and remain in Missouri at the time of death, must be tested for CWD. 6.) Animals must meet all

In Process of Developing or Implementing New or Additional CWD Regulations

See CWD Regulations. Change to occur - March 1, 2010 all CWD related regulations will be completely removed from the Wildlife Code of Missouri. The Missouri Department of Agriculture will assume the role of regulating and enforcing all CWD related regulations. The Wildlife Code of Missouir will specifically state: "Animal health standards and movement activities shall comply with all state and federal regulations. (Refer to Missouri Department of Agriculture for applicable Chronic Wasting Disease rules and regulations.)"

CWD Testing Program for Captive Cervids

Voluntary monitoring program developed and implemented in 2002 for captive industry. 1.) All captive whitetail deer that enter Missouri, (imports) and remain in Missouri at time of death, must be tested for CWD.

CWD Testing Program for Wildlife

Tested more than 22,000 free-ranging deer during 2002-2004 with a sample of at least 200 deer per county. No CWD was found. The Department of Conservation continues to test sick deer and encourages hunters and the public to report deer than appear to be ill. Targeted surveillance of obviously sick animals will continue indefinitely. In 2007, the Department began a three-year program of CWD testing in which one-third of the state was sampled annually. In 2007 1,221 CWD samples were collected from adult bucks by trained taxidermist and an additional 9 sick deer tested in the northern third of the state and in 2008, 1,194 samples of adult bucks were collected and tested in the central third of the state. No CWD was found.

Baiting Banned

Hunting deer, turkey and waterfowl over bait has been prohibited for many years in Missouri.

Feeding Banned

No Ban.

Ban on Movement of Animal Parts

No ban, encourage hunters to import only boned out meat and clean skull plates. We employ media releases to inform hunters of regulations in other states Missouri residents commonly hunt. Change to occur - March 1, 2010 the following verbiage is being added to the Wildlife Code of Missouri "Wildlife legally taken and exported from another state or country may also be shipped into Missouri by common carrier, except cervid carcasses or cervid carcass parts. The importation, transportation, or possession of cervid carcasses or cervid carcass parts taken from or obtained outside of Missouri is prohibited, except for meat that is cut and wrapped; meat that has been boned out; quarters or other portions of meat with no part of the spinal column or head attached; hides or capes from which all excess tissue has been removed; antlers; antlers attached to skull plates or skulls cleaned of all muscle and brain tissue; upper canine teeth; and finished taxidermy products. Carcasses or parts of carcasses with the spinal column or head attached my be transported into the state only if they are reported to an agent of the department within twenty-four (24) hours of entering the state and then taken to a license meat processor or taxidermist within seventy-two (72) hours of entry. Licensed meat processors and taxidermists shall dispose of the discarded tissue in a properly permitted landfill.

CWD Found in Captive Cervids

No

UPDATE

(yes, February 25, 2010 Chronic Wasting Disease Found in Captive Deer The Missouri Departments of Agriculture, Conservation and Health and Senior Services and the U.S. Department of Agriculture announced today that a captive white-tailed deer in Linn County, Missouri has tested positive for Chronic Wasting Disease (CWD).)

http://mda.mo.gov/news/2010/Chronic_Wasting_Disease_Found_in_Captive_Deer



CWD Found in Free- Ranging Cervids

No

http://www.cwd-info.org/pdf/CWDRegstableState.pdf




Chronic Waste Disease—Missouri continues to monitor the captive cervid herds resulting in 628 tested in 2009. In March 2010, the Missouri Department of Conservation will relinquish CWD monitoring of whitetail to the Department of Agriculture.

http://mda.mo.gov/YearlyReview2009.pdf



12/31/2009

(E) Chronic Wasting Disease. 1. Captive cervids will not be allowed to enter the state if, within the last five (5) years, the animal— A. Originates from an area or has been in an area that has been reported as a Chronic Wasting Disease (CWD) endemic area; and B. Originates from a CWD positive captive herd. 2. Elk, elk-hybrids, red deer, roe deer, white-tailed deer, mule deer, sika deer, and moose entering Missouri from any state must have participated in a CWD certification program for five (5) consecutive years. Other cervids, including but not limited to reindeer, mutjac, and fallow deer, must have participated in a certification program recognized by the state of origin prior to entering Missouri. Original anniversary date must be listed on the Certificate of Veterinary Inspection. 3. Captive cervids moving between publicly- owned American Zoos and Aquariums (AZA)-accredited zoos must meet the CWD certification program requirements.

http://www.sos.mo.gov/adrules/csr/current/2csr/2c30-2.pdf




Rules of Department of Agriculture Division 30?Animal Health Chapter 2?Health Requirements for Movement of Livestock, Poultry and Exotic Animals

(6/30/06)

(D) Chronic Wasting Disease (CWD). 1. Captive cervids will not be allowed to enter the state if within the last five (5) years the animal: A. Is from an area that has been reported as a chronic wasting disease (CWD) endemic area; B. Has been in a CWD endemic area; or C. Originates from a CWD positive captive herd. 2. Until 2008, elk, elk-hybrids, red deer, sika deer, white-tailed deer, and mule deer entering Missouri from any state must have participated in a surveillance program since 2002. Beginning in 2008, surveillance will be required for five (5) consecutive years before the above-mentioned animals will be allowed to enter Missouri from any state. 3. Other captive cervids other than elk, elk-hybrids, red deer, sika deer, white-tailed deer and mule deer must have participated in a surveillance program recognized by the state of origin prior to entering Missouri. 4. All captive white-tailed deer that enter Missouri with two (2) years of CWD monitoring in an approved surveillance program and remained in Missouri at the time of death, must be tested for CWD.

https://www.sos.mo.gov/adrules/csr/previous/2csr/2csr0808/2c30-2.pdf




2005

(D) Chronic Wasting Disease (CWD). 1. Captive cervids will not be allowed to enter the state if within the last five (5) years the animal: A. Is from an area that has been reported as a chronic wasting disease (CWD) endemic area; B. Has been in a CWD endemic area; or C. Originates from a CWD positive captive herd. 2. Until 2008, elk, elk-hybrids, red deer, sika deer, white-tailed deer, and mule deer entering Missouri from any state must have participated in a surveillance program since 2002. Beginning in 2008, surveillance will be required for five (5) consecutive years before the above-mentioned animals will be allowed to enter Missouri from any state. 3. Other captive cervids other than elk, elk-hybrids, red deer, sika deer, white-tailed deer and mule deer must have participated in a surveillance program recognized by the state of origin prior to entering Missouri. 4. All captive white-tailed deer that enter Missouri with two (2) years of CWD monitoring in an approved surveillance program and remained in Missouri at the time of death, must be tested for CWD.

https://www.sos.mo.gov/adrules/csr/previous/2csr/2csr0206/2c30-2.pdf





Title 2—DEPARTMENT OF AGRICULTURE

Division 30—Animal Health

Chapter 2—Health Requirements for Movement of Livestock, Poultry and Exotic Animals

EMERGENCY AMENDMENT

2 CSR 30-2.010 Health Requirements Governing the Admission of Livestock, Poultry and Exotic Animals Entering Missouri. The division is amending subsection (13)(D).

PURPOSE: This emergency amendment addresses the financial crisis affecting Missouri white-tail deer farmers due to the importation restriction implemented during the first years of chronic wasting disease (CWD) control and eradication efforts throughout the nation by reducing the required level of surveillance for CWD in order for white-tail deer to enter Missouri.

EMERGENCY STATEMENT: There is a compelling governmental interest in preserving the white-tail deer industry which has been seriously affected by a 2002 rule change. This emergency amendment will provide significant regulatory and financial relief for captive white-tail deer producers and big game hunting preserve operators. The emergency passage of this amendment will allow millions of dollars to be injected into the state’s economy this year, help maintain employment in the white-tail deer industry and could save Missouri white-tail deer operations from being forced out of business. The Missouri Department of Agriculture (MDA) values and supports a prosperous agricultural economy and supports and promotes the preservation and enhancement of our environment and agricultural resources. The Missouri Department of Agriculture supports and promotes the safe, profitable and environmentally responsible operation of white-tail deer agricultural endeavors.

In order to protect Missouri livestock and existing herds of elk, elkhybrids, white-tailed deer and mule deer from importation of diseases that pose a potential threat to the public health, safety and welfare, the Department of Agriculture proposed a rule change in 2002 to limit and monitor the movement of captive cervids into the state. The proposed change, dealing with the diseases of brucellosis, tuberculosis and chronic wasting disease (CWD), was adopted. The amended rule requires captive cervids entering Missouri to have an interstate shipping permit issued by the state veterinarian’s office and a Certificate of Veterinary Inspection. The rule stipulates testing requirements for the movement of captive cervids into the state. The rule also states that cervids “from all states must have participated in a surveillance program for at least three (3) years prior to entering Missouri.”

Although the department has received little or no negative feedback regarding the cost associated with testing the animals, an unintended consequence of the rule change has negatively impacted the profitability of the industry. Very few herds in the United States have been in a surveillance program for three (3) years or longer and ironically those herds that have are in states that have been reported to have chronic wasting disease endemic areas. With the three (3) year surveillance requirement in place farmers engaged in big game hunting operations have little or no opportunity to import large trophy deer for their hunting preserves and breeders have difficulty importing ideal breeding stock. The inability to import the very best stock has cost the industry more than three (3) million dollars in lost hunt sales alone. Since more than ninety percent (90%) of the white-taildeer hunters at Missouri’s big game preserves are from out-of-state there has been a substantial revenue loss to Missouri’s tourism industry as well. The local economies in areas surrounding breeding farms and hunting preserves have also seen revenues decline and some of the operations have been forced to lay off employees. If the rule is not changed in time for the preserves to benefit from this years hunting season not only will there be a significant loss in revenue to the industry and the Missouri economy, it is feared that more operators will be forced out of the business.

Prior to the implementation of the rule change more than two thousand (2,000) white-tail deer were annually exported to other states with sales totaling more than three (3) million dollars. Since the 2002 three (3) year surveillance requirement was enacted, sales of whitetail deer at Missouri livestock markets have dropped by more than ninety percent (90%) and the top selling price for a buck has plummeted from eleven thousand dollars ($11,000) to one thousand dollars ($1,000) in the same period. This once thriving segment of the industry is now all but nonexistent. Since the rule was amended the total economic impact in lost revenue in Missouri has been estimated to be more than ten (10) million dollars annually. Although this amount may seem small compared to Missouri’s total economy it is a substantial amount for one (1) small segment of Missouri agriculture. In the two (2) years since the rule change, extensive testing and epidemiologic studies have been conducted nationwide. The results have revealed no new infected herds outside the original eleven (11) states where the disease had been previously diagnosed. While the rule change lowers the required number of years for CWD surveillance from a three (3)-year to two (2)-year status it further requires that all captive white-tail deer entering Missouri with a two (2)-year status be tested for CWD upon the death of the animal regardless of the cause of death. MDA and its Animal Health Division are satisfied that the emergency rule change will continue to protect the public health, safety and welfare as well as Missouri livestock and cervids through surveillance and testing, while providing needed and immediate financial relief for the white-tail deer industry. The Missouri Department of Agriculture strongly supports the emergency status of this rule change.

A proposed amendment, which covers the same material, is published in this issue of the Missouri Register. The scope of this emergency amendment is limited to the circumstances creating the emergency and complies with the protections extended in the Missouri and United States Constitutions. The Department of Agriculture believes this emergency amendment is fair to all interested persons and parties under the circumstances. Emergency amendment filed August 23, 2004, effective September 3, 2004, expires March 1, 2004.

(13) Miscellaneous and Exotic Animals. All exotic animals must be accompanied by an official Certificate of Veterinary Inspection showing an individual listing of the common and scientific name(s) of the animal(s) and appropriate descriptions of animal(s) such as sex, age, weight, coloration and the permanent tag number, brand or tattoo identification.

(D) Captive cervids, prior to entering Missouri, must have an entry permit issued by the state veterinarian’s office and a Certificate of Veterinary Inspection. Captive cervids that enter Missouri must be in compliance with the guidelines as incorporated by reference to the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999 and Brucellosis in Cervidae: Uniform Methods and Rules, Effective September 30, 1998.

1. All sexually intact animals six (6) months of age or older, not under quarantine and not affected with brucellosis, must test negative for brucellosis within thirty (30) days prior to movement, except:

A. Brucellosis-free herd—captive cervids originating from certified brucellosis-free herds may enter on herd status without additional testing provided the certified herd number and current test date is shown on the Certificate of Veterinary Inspection;

B. Brucellosis-monitored herd—all sexually intact animals six (6) months of age or older must test negative for brucellosis within ninety (90) days prior to interstate movement.

2. Captive cervids not known to be affected with or exposed to tuberculosis and not in a status herd, as defined in the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999, must have two (2) negative tuberculosis tests, not less than ninety (90) days apart, using the single cervical method. The second test must be within ninety (90) days prior to movement. Both negative test dates must be listed on the Certificate of Veterinary Inspection. Animals must have been isolated from other captive cervids during the testing period.

3. Movement from status herds.

A. Accredited herd—captive cervids originating from accredited tuberculosis-free cervid herd as defined by the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999, may enter on herd status without additional testing provided the accredited herd number and current test date is shown on the Certificate of Veterinary Inspection.

B. Qualified herd—captive cervids originating from a qualified herd as defined by the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999, must have one (1) negative tuberculosis test, using the single cervical method, within ninety (90) days prior to the date of movement.

C. Monitored herd—captive cervids originating from a monitored herd as defined by the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January, 22, 1999, must have one (1) negative tuberculosis test, using the single cervical method, within ninety (90) days prior to date of movement.

D. Captive cervids less than twelve (12) months of age that originate from and were born in qualified or monitored herds may be moved without further tuberculosis testing, provided that they are accompanied by a certificate stating that such captive cervids originated from such herds and have not been exposed to captive cervids from a lower status herd.

4. Captive cervids from an area that has been reported as a chronic wasting disease (CWD) endemic area or any cervid that has been in an endemic area in the last five (5) years will not be allowed to enter Missouri.

5. Elk, elk-hybrids, [white-tailed deer] and mule deer from all states must have participated in a surveillance program for at least three (3) years prior to entering Missouri. Other captive cervids other than white-tailed deer must have participated in a surveillance program recognized by the state of origin prior to entering Missouri.

6. White-tailed deer from all states must have participated in a surveillance program for at least two (2) years prior to entering Missouri. Other captive cervids must have participated in a surveillance program recognized by the state of origin prior to entering Missouri.

7. All captive white-tailed deer that enter Missouri with a two (2)-year status in a CWD surveillance program and remain in Missouri at the time of death must be tested for CWD.

AUTHORITY: section 267.645, RSMo 2000. This version of rule filed Jan. 24, 1975, effective Feb. 3, 1975. For intervening history, please consult the Code of State Regulations. Emergency amendment filed Aug. 23, 2004, effective Sept. 3, 2004, expires March 1, 2005. A proposed amendment covering this same material is published in this issue of the Missouri Register.

Title 2—DEPARTMENT OF AGRICULTURE

Division 30—Animal Health

Chapter 6—Livestock Markets

EMERGENCY AMENDMENT

2 CSR 30-6.020 Duties and Facilities of the Market/Sale Veterinarian. The department is proposing to amend subsection (8)(D).

PURPOSE: This emergency amendment addresses the financial crisis affecting Missouri white-tail deer farmers due to the importation restriction implemented during the first years of chronic wasting disease (CWD) control and eradication efforts throughout the nation by reducing the required level of surveillance for CWD in order for white-tail deer to enter Missouri.

EMERGENCY STATEMENT: There is a compelling governmental interest in preserving the white-tail deer industry which has been seriously affected by a 2002 rule change. This emergency amendment will provide significant regulatory and financial relief for captive white-tail deer producers and big game hunting preserve operators. The emergency passage of this amendment will allow millions of dollars to be injected into the state’s economy this year, help maintain employment in the white-tail deer industry and could save Missouri white-tail deer operations from being forced out of business. The Missouri Department of Agriculture (MDA) values and supports a prosperous agricultural economy and supports and promotes the preservation and enhancement of our environment and agricultural resources. The Missouri Department of Agriculture supports and promotes the safe, profitable and environmentally responsible operation of white-tail deer agricultural endeavors. In order to protect Missouri livestock and existing herds of elk, elkhybrids, white-tailed deer and mule deer from importation of diseases that pose a potential threat to the public health, safety and welfare, the Department of Agriculture proposed a rule change in 2002 to limit and monitor the movement of captive cervids into the state. The proposed change, dealing with the diseases of brucellosis, tuberculosis and chronic wasting disease (CWD), was adopted. The amended rule requires captive cervids entering Missouri to have an interstate shipping permit issued by the state veterinarian’s office and a Certificate of Veterinary Inspection. The rule stipulates testing requirements for the movement of captive cervids into the state. The rule also states that cervids “from all states must have participated in a surveillance program for at least three (3) years prior to entering Missouri.”

Although the department has received little or no negative feedback regarding the cost associated with testing the animals, an unintended consequence of the rule change has negatively impacted the profitability of the industry. Very few herds in the United States have been in a surveillance program for three (3) years or longer and ironically those herds that have are in states that have been reported to have chronic wasting disease endemic areas. With the three (3) year surveillance requirement in place farmers engaged in big game hunting operations have little or no opportunity to import large trophy deer for their hunting preserves and breeders have difficulty importing ideal breeding stock. The inability to import the very best stock has cost the industry more than three (3) million dollars in lost hunt sales alone. Since more than ninety percent (90%) of the white-tail deer hunters at Missouri’s big game preserves are from out-of-state there has been a substantial revenue loss to Missouri’s tourism industry as well. The local economies in areas surrounding breeding farms and hunting preserves have also seen revenues decline and some of the operations have been forced to lay off employees. If the rule is not changed in time for the preserves to benefit from this year’s hunting season not only will there be a significant loss in revenue to the industry and the Missouri economy, it is feared that more operators will be forced out of the business.

Prior to the implementation of the rule change more than two thousand (2,000) white-tail deer were annually exported to other states with sales totaling more than three (3) million dollars. Since the 2002 three (3) year surveillance requirement was enacted, sales of whitetail deer at Missouri livestock markets have dropped by more than ninety percent (90%) and the top selling price for a buck has plummeted from eleven thousand dollars ($11,000) to one thousand dollars ($1,000) in the same period. This once thriving segment of the industry is now all but nonexistent. Since the rule was amended the total economic impact in lost revenue in Missouri has been estimated to be more than ten (10) million dollars annually. Although this amount may seem small compared to Missouri’s total economy it is a substantial amount for one (1) small segment of Missouri agriculture. In the two (2) years since the rule change, extensive testing and epidemiologic studies have been conducted nationwide. The results have revealed no new infected herds outside the original eleven (11) states where the disease had been previously diagnosed. While the rule change lowers the required number of years for CWD surveillance from a three (3)-year to two (2)-year status it further requires that all captive white-tail deer entering Missouri with a two (2)-year status be tested for CWD upon the death of the animal regardless of the cause of death. MDA and its Animal Health Division are satisfied that the emergency rule change will continue to protect the public health, safety and welfare as well as Missouri livestock and cervids through surveillance and testing, while providing needed and immediate financial relief for the white-tail deer industry.

The Missouri Department of Agriculture strongly supports the emergency status of this rule change.

A proposed amendment, which covers the same material, is published in this issue of the Missouri Register. The scope of this emergency amendment is limited to the circumstances creating the emergency and complies with the protections extended in the Missouri and United States Constitutions. The Department of Agriculture believes this emergency amendment is fair to all interested persons and parties under the circumstances. Emergency amendment filed August 23, 2004, effective September 3, 2004 expires March 1, 2005.

(8) Miscellaneous and Exotic Animals. All exotic animals presented for exchange, barter, lease or sale at a licensed livestock market/sale must be accompanied by an official Certificate of Veterinary Inspection showing an individual listing of the common and scientific name(s) of the animal(s) and appropriate descriptions of animal(s) such as sex, age, weight, coloration and the permanent tag number, brand or tattoo identification.

(D) Captive cervids from out-of-state that arrive at a market/sale in Missouri must have an entry permit issued by the state veterinarian’s office and a Certificate of Veterinary Inspection. Captive cervids from out-of-state that arrive at a market/sale must be in compliance with the guidelines as incorporated by reference to the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999 and Brucellosis in Cervidae: Uniform Methods and Rules, Effective September 30, 1998. Movement of Missouri origin captive cervids must be in compliance with Missouri’s intrastate movement regulations.

1. All sexually intact animals six (6) months of age or older, not under quarantine and not affected with brucellosis, must test negative for brucellosis within thirty (30) days prior to arrival at the market/ sale, except:

A. Brucellosis-free herd—captive cervids originating from certified brucellosis-free herds may be sold through a market/sale on the current herd number and test date;

B. Brucellosis-monitored herd—all sexually intact animals six (6) months of age or older must test negative for brucellosis within ninety (90) days prior to arrival at the market/sale.

2. Captive cervids not known to be affected with or exposed to tuberculosis and not in a status herd, as defined in the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999, must have two (2) negative tuberculosis tests, not less than ninety (90) days apart, using the single cervical method. The second test must be within ninety (90) days prior to arrival at the market/sale.

3. Movement from status herds.

A. Accredited herds—captive cervids originating from accredited tuberculosis-free cervid herd as defined by the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999, may be sold through a market/sale on the current herd number and test date.

B. Qualified herd—captive cervids originating from a qualified herd as defined by the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January 22, 1999, must have one (1) negative tuberculosis test, using the single cervical method, within ninety (90) days prior to arrival at the market/sale.

C. Monitored herd—captive cervids originating from a monitored herd as defined by the Bovine Tuberculosis Eradication Uniform Methods and Rules, Effective January, 22, 1999, must have one (1) negative tuberculosis test, using the single cervical method, within ninety (90) days prior to arrival at the market/sale.

D. Captive cervids less than twelve (12) months of age that originate from and were born in qualified or monitored herds may be sold through a market/sale without further tuberculosis testing, provided that they are accompanied by a certificate stating that such captive cervids originated from such herds and have not been exposed to captive cervids from a lower status herd.

4. Captive cervids from an area that has been reported as a chronic wasting disease (CWD) endemic area or any cervid that has been in an endemic area in the last five (5) years will not be allowed to move through a Missouri livestock market/sale.

5. Elk, elk-hybrids[, white-tailed deer] and mule deer from all states must have participated in a surveillance program for at least three (3) years prior to moving through a Missouri livestock market/ sale. Other captive cervids other than white-tailed deer must have participated in a surveillance program recognized by the state of origin prior to moving through a Missouri livestock market/sale.

6. White-tailed deer from all states must have participated in a surveillance program for at least two (2) years prior to entering Missouri. Other captive cervids must have participated in a surveillance program recognized by the state of origin prior to entering Missouri.

7. All captive white-tailed deer that enter Missouri with a two (2)-year status in a CWD surveillance program and remain in Missouri at the time of death must be tested for CWD. AUTHORITY: section 277.160, RSMo 2000. Original rule filed June 15, 1990, effective Dec. 31, 1990. For intervening history, please consult the Code of State Regulations. Emergency amendment filed March 5, 2004, effective March 15, 2004, expires Aug. 27, 2004. Amended: Filed March 5, 2004. Emergency amendment filed Aug. 23, 2004, effective Sept. 3, 2004, expires March 1, 2005. A proposed amendment covering this same material is published in this issue of the Missouri Register.

http://www.sos.mo.gov/adrules/moreg/previous/2004/v29n19/v29n19a.pdf




Friday, January 15, 2010

Sixteen Additional Deer Test Positive for Chronic Wasting Disease In Hampshire County, West Virginia


http://chronic-wasting-disease.blogspot.com/2010/01/sixteen-additional-deer-test-positive.html



Thursday, January 21, 2010

Chronic Wasting Disease Found in White-tailed Deer in Virginia


http://chronic-wasting-disease.blogspot.com/2010/01/chronic-wasting-disease-found-in-white.html



CWD ILLINOIS UPDATE 2010 *Update January 6, 2010


http://chronic-wasting-disease.blogspot.com/2010/01/cwd-illinois-update-2010.html



Thursday, January 21, 2010 Kansas has more CWD cases


http://chronic-wasting-disease.blogspot.com/2010/01/kansas-has-more-cwd-cases.html



Sunday, December 06, 2009

Detection of Sub-Clinical CWD Infection in Conventional Test-Negative Deer Long after Oral Exposure to Urine and Feces from CWD+ Deer


http://chronic-wasting-disease.blogspot.com/2009/12/detection-of-sub-clinical-cwd-infection.html



Tuesday, June 16, 2009

Infectious Prions in Pre-Clinical Deer and Transmission of Chronic Wasting Disease Solely by Environmental Exposure


http://chronic-wasting-disease.blogspot.com/2009/06/infectious-prions-in-pre-clinical-deer.html



Friday, December 11, 2009

CWD, FECES, ORAL LESIONS, Aerosol and intranasal transmission


http://chronic-wasting-disease.blogspot.com/2009/12/cwd-feces-oral-lesions-aerosol-and.html



Wednesday, October 14, 2009

Detection of protease-resistant cervid prion protein in water from a CWD-endemic area


http://chronic-wasting-disease.blogspot.com/2009/10/detection-of-protease-resistant-cervid.html



AS THE CROW FLIES, SO DOES CWD

Sunday, November 01, 2009

American crows (Corvus brachyrhynchos) and potential spreading of CWD through feces of digested infectious carcases


http://chronic-wasting-disease.blogspot.com/2009/11/american-crows-corvus-brachyrhynchos.html


Sunday, October 04, 2009

CWD NEW MEXICO SPREADING SOUTH TO TEXAS 2009



http://chronic-wasting-disease.blogspot.com/2009/10/cwd-new-mexico-spreading-south-to-texas.html



Wednesday, January 07, 2009

CWD to tighten taxidermy rules Hunters need to understand regulations


http://chronic-wasting-disease.blogspot.com/2009/01/cwd-to-tighten-taxidermy-rules-hunters.html



Monday, August 24, 2009

Third International CWD Symposium July 22-24, 2009 - Park City, Utah ABSTRACTS


http://chronic-wasting-disease.blogspot.com/2009/08/third-international-cwd-symposium-july.html



Deer Carcass Decomposition and Potential Scavenger Exposure to Chronic Wasting Disease


http://chronic-wasting-disease.blogspot.com/2009/07/deer-carcass-decomposition-and.html



CWD, GAME FARMS, BAITING, AND POLITICS


http://chronic-wasting-disease.blogspot.com/2009/01/cwd-game-farms-baiting-and-politics.html



NOT only muscle, but now fat of CWD infected deer holds infectivity of the TSE (prion) agent. ...TSS

Monday, July 06, 2009

Prion infectivity in fat of deer with Chronic Wasting Disease


http://chronic-wasting-disease.blogspot.com/2009/07/prion-infectivity-in-fat-of-deer-with.html



Friday, February 20, 2009

Both Sides of the Fence: A Strategic Review of Chronic Wasting Disease


http://chronic-wasting-disease.blogspot.com/2009/02/both-sides-of-fence-strategic-review-of.html



Saturday, September 06, 2008

Chronic wasting disease in a Wisconsin white-tailed deer farm 79% INFECTION RATE

Contents: September 1 2008, Volume 20, Issue 5

snip...see full text ;



http://chronic-wasting-disease.blogspot.com/2008/11/commentary-crimes-hurt-essence-of.html



Tuesday, January 27, 2009

Chronic Wasting Disease found in a farmed elk from Olmsted County ST. PAUL, Minn. FOR IMMEDIATE RELEASE: Monday, January 26, 2009



http://chronic-wasting-disease.blogspot.com/2009/01/chronic-wasting-disease-found-in-farmed.html



Saturday, January 24, 2009

Research Project: Detection of TSE Agents in Livestock, Wildlife, Agricultural Products, and the Environment Location: 2008 Annual Report


http://bse-atypical.blogspot.com/2009/01/research-project-detection-of-tse.html



2008 CWD Laboratory Testing for Wild White-tailed Deer


http://www.michigan.gov/emergingdiseases/0,1607,7-186-25806-202922--,00.html



Wednesday, January 07, 2009

CWD to tighten taxidermy rules Hunters need to understand regulations


http://chronic-wasting-disease.blogspot.com/2009/01/cwd-to-tighten-taxidermy-rules-hunters.html



Thursday, December 25, 2008 Lions and Prions and Deer Demise


http://chronic-wasting-disease.blogspot.com/2008/12/lions-and-prions-and-deer-demise.html


http://chronic-wasting-disease.blogspot.com/



CWD Update 95 January 21, 2010



http://wildlifedisease.nbii.gov/documents/CWD%20Updates/update%2095.pdf



also see ;



http://chronic-wasting-disease.blogspot.com/


TSS

Labels: , , ,

Monday, February 22, 2010

Aerosol and Nasal Transmission of Chronic Wasting Disease in Cervidized Mice

Published online ahead of print on 17 February 2010 as doi:10.1099/vir.0.017335-0 J Gen Virol (2010), DOI 10.1099/vir.0.017335-0 © 2010 Society for General Microbiology

Aerosol and Nasal Transmission of Chronic Wasting Disease in Cervidized Mice

Nathaniel D Denkers1, Davis M Seelig1, Glenn C. Telling2 and Edward A Hoover, Jr1,3

1 Colorado State University; 2 University of Kentucky Medical Center

3 E-mail: edward.hoover@colostate.edu

Little is known regarding the potential risk posed by aerosolized prions. Chronic wasting disease (CWD) is transmitted horizontally, almost surely by mucosal exposure, and CWD prions are present in saliva and urine of infected animals. However, whether CWD may be transmissible by the aerosol or nasal route is not known. To address this question, FVB mice transgenetically expressing the normal cervid PrPC protein [Tg(cerPrP) mice] were exposed to CWD prions by either nose-only aerosol exposure or by drop-wise instillation into the nostrils. Mice were monitored for signs of disease for up to 755 days post inoculation (dpi) and by examination of tissues for lesions and PrPCWD after necropsy. In particular, nasal mucosa, vomeronasal organ, lungs, lymphoid tissue, and the brain were assessed for PrPCWD by western blotting and immunohistochemistry. Six of 7 aerosol-exposed Tg(cerPrP) mice developed clinical signs of neurologic dysfunction mandating euthanasia between 411 and 749 dpi. In all these mice, CWD infection was confirmed by detection of spongiform lesions and PrPCWD in the brain. Two of 9 intra-nasally inoculated Tg(cerPrP) mice also developed TSE associated with PrPCWD between 417 and 755 dpi. No evidence of PrPCWD was detected in CWD-inoculated Tg(cerPrP) mice examined at pre-terminal time points. These results demonstrate that CWD can be transmitted by aerosol (as well as nasal) exposure and suggest that exposure via the respiratory system merits consideration for prion disease transmission and biosafety.

Received 30 October 2009; accepted 15 February 2010.


http://vir.sgmjournals.org/cgi/content/abstract/vir.0.017335-0v1



Friday, December 11, 2009

CWD, FECES, ORAL LESIONS, Aerosol and intranasal transmission


http://chronic-wasting-disease.blogspot.com/2009/12/cwd-feces-oral-lesions-aerosol-and.html




Tuesday, February 09, 2010


Chronic Wasting Disease: Surveillance Update North America: February 2010


http://chronic-wasting-disease.blogspot.com/2010/02/chronic-wasting-disease-surveillance.html




see CWD archive here ;


http://chronic-wasting-disease.blogspot.com/




TSS

Labels: , , ,

Tuesday, February 09, 2010

Chronic Wasting Disease: Surveillance Update North America: February 2010

Updates Chronic Wasting Disease: Surveillance Update: February 1, 2010

Testing of heads from the fall hunting seasons continues. To date [Feb 1/10], we have completed tests on 3537 heads since September 1, 2009. The program has detected 10 new cases of CWD in wild deer, all of which are mule deer. New outlier cases were detected well up the Red Deer River at the west end of Wildlife Management Unit (WMU) 151 and far to the south in WMU 119. The 3 most recent cases were found in WMU 232, 202, and 236. The infected deer found in WMU 232 and 236 are quite close to other known cases; the infected deer in WMU 202 is somewhat distant from other cases. The cumulative total of confirmed cases of CWD in wild deer in Alberta is 72.


http://www.srd.alberta.ca/BioDiversityStewardship/WildlifeDiseases/ChronicWastingDisease.aspx



Current Distribution Maps of CWD Positive Wild Deer in Saskatchewan (updated on January 2010)


http://www.environment.gov.sk.ca/adx/aspx/adxGetMedia.aspx?DocID=9dfe485d-6995-4b89-b928-42d48bdcd434&MediaID=2105&Filename=CWD+Positive+Wild+Deer+in+2009.pdf&l=English


http://www.environment.gov.sk.ca/Default.aspx?DN=171eb429-d529-4635-9877-d01c8f5b48b1


http://www.environment.gov.sk.ca/Default.aspx?DN=ff4336ff-98fe-43a1-98d0-8608c8aca619



Yukon

Chronic Wasting Disease (CWD): Notice to Yukoners hunting deer and elk outside the territory Environment Yukon staff track the emergence and transmission of wildlife diseases in North America. We recognize that animal carcasses and offal transported by hunters from region to region can pose significant risks to local wildlife by transmitting disease and disease-causing agents. Chronic Wasting Disease is a new and growing threat to wildlife populations– particularly deer and elk. Although the possibility of importing this disease to the Yukon is remote, hunters are asked to ensure: that the brain, tonsils (throat) and eyes, spinal cord/backbone and all offal are removed and disposed of prior to returning to the Yukon. (The best practice would be to bring only the cleaned skull cap and antlers and edible meat and organs.) that all butchering scraps and bones be properly disposed of (in a secure Yukon landfill). Domestic and wild animals should have no access to these scraps. For additional information on either of these issues, please contact Animal Health Coordinator Philip Merchant at Environment Yukon at (867) 667-5285.



http://www.environmentyukon.gov.yk.ca/huntingtrapping/documents/hunting_regs_0910web.pdf



PROTOCOL RESPECTING THE IMPORTATION OF CERVIDS INTO QUÉBEC FROM OTHER PROVINCES OR COUNTRIES UNDER THE ANIMAL HEALTH PROTECTION ACT (R.S.Q., c. P-42) April 2009



http://www.mapaq.gouv.qc.ca/NR/rdonlyres/DD303EC9-E361-428D-9667-61F11AE7C7D5/0/englishversionbeginningOctober15th2005.pdf



Policy Proposal Notice: EBR Registry Number: 010-8462 Title: Live Cervid Importation Permit Policy

Ministry: Ministry of Agriculture, Food and Rural Affairs Date Proposal loaded to the Registry: December 14, 2009

Live Cervid Importation Permit Policy in support of a proposed amendment to O. Reg. 666/98 (Possession, Buying and Selling of Wildlife) under the Fish and Wildlife Conservation Act, 1997 (the “Act”), that would prohibit the transport into Ontario of live, captive white-tailed deer, elk, moose, caribou and their offspring into Ontario, except under a permit issued under the Act, in order to minimize the risk of entry of Chronic Wasting Disease into Ontario.


http://www.ebr.gov.on.ca/ERS-WEB-External/displaynoticecontent.do?noticeId=MTA4MzA3&statusId=MTYyNjk0&language=en



Proposal to Prohibit Importation of Live Cervids into Ontario

A regulation notices has been posted on the Environmental Registry proposing to prohibit the importation of live captive white-tailed deer, elk, moose, caribou and/or their hybrids into Ontario, unless done so under an authorization issued under the Fish and Wildlife Conservatin Act. The notice is available for review by entering Registry Number 010-8244 at this location: Environmental Registry. The comment period for this notice is December 14 to January 28, 2010.

Elk Management Plan

A notice has been posted on the Environmental Registry proposing an Elk Management Plan to ensure that Ontario's elk management program supports sustainable elk populations. This notice is available for review by entering the Registry Number 010-8381 at this location: Environmental Registry. The comment period for this notice is November 23, 2009 to January 7, 2010.

The following documents are part of this notice:

Draft Elk Management Plan – Executive Summary (PDF, 43 kb) Draft Elk Management Plan (PDF, 373 kb)

Moose Management Policy and Guidelines - Decision

A decision notice has been posted on the Environmental Registry concerning the Moose Management Policy and supporting documents: Moose Population Objectives Setting Guidelines and Moose Harvest Management Guidelines. This notice is available for review by entering the Registry Number 010-5396 at this location: Environmental Registry.

The following documents are part of this notice:


http://www.mnr.gov.on.ca/en/Business/FW/2ColumnSubPage/261742.html


http://www.omafra.gov.on.ca/english/livestock/alternat/deerelk.htm



Ontario's CWD Surveillance and Response Plan


http://www.mnr.gov.on.ca/en/Business/FW/2ColumnSubPage/STEL02_168765.html


http://www.inspection.gc.ca/english/anima/disemala/cwdmdc/cwdmdce.shtml



CWD confirmed south of TransCanada

SW Sk Content - Environment Thursday, 04 February 2010 20:34 By Elizabeth Huber Prairies

Following the 2009 hunting season, the province of Saskatchewan received 3,200 deer heads to sample for chronic wasting disease.

Testing, not quite complete, has shown 38 new positive cases within Saskatchewan in 2009.

It is a provincial sampling effort, although it cannot be enforced “we certainly ask for (hunters’) participation,” said Penny Lalonde, provincial licensing specialist.

The monitoring and surveillance of the disease through harvesting the animals helps keep the numbers low enough so the prevalence stays low, she added.

In Saskatchewan, 2008 monitoring practices also revealed three positive cases in elk, but there haven’t been anymore since then, according to numbers provided by the fish and wildlife branch of the ministry of environment.

In Alberta, as of Jan. 15, 2468 heads had been tested since Sept. 1, 2009 and revealed seven new cases of CWD in wild deer. The total is now 69 confirmed cases of CWD in wild deer in Alberta.

Although a case of the disease was found on an Alberta farmed elk in 2002 it has not yet been found in the wild populations, noted Darcy Whiteside, spokesperson for the Ministry of sustainable Resource Development.

Alberta concentrates their sampling along the border region with Saskatchewan from north of Lloydminster to south of the TransCanada Highway and identifys the zones as mandatory deer head submission.

Last year, the first case was found north of Lloydminster and this year, the first case was discovered below Highway 1, noted Whiteside. The majority of cases have been found near Empress and Edgerton.

In Saskatchewan, three clusters of CWD areas have been identified near Nipawin, Lloydminster and North Battleford and the South Saskatchewan River north of Swift Current.

The surrounding wildlife management zones were designated as earn-a-buck zones in 2009, which means hunters must turn in two doe heads before receiving a buck tag. It is the first year the wildlife management Zone 45 near North Battleford was identified in the program.

It is very difficult to say if the disease is increasing in prevalence or not, said Yeen Ten Hwant, wildlife health specialist with the fish and wildlife branch, because the calculation is dependent upon the number of samples submitted in a year.

“It has been holding steady between 1.5 and two per cent,” said Hwant. Working with neighbouring jurisdictions in Canada and the States is important for understanding CWD, noted Whiteside and Hwang. “We know that it is not a disease that is not a natural part of the Alberta Ecosystem, environment, habitat,” added Whiteside.

They need to also consider how hunters actions can assist with the disease management as well, he said. For example, looking at proper techniques to ensure transmission doesn't happen when transferring the meat and moving the meat, carcasses, hides and heads around.


http://www.prairiepost.com/news/sw-sask-news/environment/622-cwd-confirmed-south-of-transcanada.html



The Most Pervasive Prion Disease

Chronic wasting disease continues to spread and shows no signs of slowing down.

by Sandra Haney

Dr. Frederick Leighton from the Canadian Cooperative Wildlife Health Centre recently presented an overview on chronic wasting disease (CWD) to PrioNet’s Board of Directors. As PrioNet implements its updated strategic plan, CWD is being targeted and PrioNet will be working towards finding out more about prion contamination in CWD-affected environments and the socioeconomic consequences of the spread of CWD. Thousands of wild deer across North America are infected by CWD mainly in the west-central United States (South Dakota, Wyoming, and Colorado) and the Canadian prairies (Saskatchewan and Alberta). CWD, a prion disease that causes chronic weight loss which leads to death, was first discovered in 1967 in mule deer at a wildlife research facility in northern Colorado. The definitive origin of CWD is currently unknown. It either came from the wild or from closed facilities, but eventually gained entry into zoos and game farms. Unfortunately, animals affected with CWD can transmit the misfolded prion protein to the environment in their saliva and excretions, such as urine and feces. These proteins are also abundant in the carcass of the animals that have died from CWD and persist in the environment even after the body has decomposed. These factors contribute significantly to the complexities of CWD transmission as well as options for control and destruction of CWD in the natural landscape. The first case of CWD in Canada was recognized in 1996 in a farmed elk in Saskatchewan. Based on import records CWD was in Canada long before this, but had gone undetected. CWD was imported into Canada from the United States in the late 1980’s in a farmed elk. Canada took strong action from 2000 to 2004 to eradicate CWD from its farmed elk populations in Saskatchewan. Forty-two farms containing approximately 18,000 animals (elk and white-tailed deer) were depopulated, costing the government about $40 million. However, eradication of CWD from Canada failed because it spread to wild deer populations before it was eradicated from farmed populations. Since 2000, wild deer with CWD are being diagnosed at increasing numbers and at multiple locations, first in Saskatchewan and now Alberta. Despite continued depopulation efforts, including wild populations, CWD continues to spread. There are several species at risk of CWD: white-tailed deer, mule deer, elk, and moose. No affected moose have been detected in Canada, but two have been found in the United States. It is not known yet whether CWD affects caribou or reindeer, however, experimental infections are currently being conducted by the Canadian Food Inspection Agency. Currently there is no evidence that CWD transmits to humans.

There appears to be barriers to transmission between species which brings hope that CWD will turn out to be like scrapie, a prion disease of sheep which is not transmissible to humans. However, the species barrier with CWD is complicated. For example, in experimental models the CWD prion from mule deer will infect other cervids and ferrets, but not hamsters. On the other hand, CWD established in ferrets will transmit to hamsters (see sidebar). With the enormous quantity of CWD prion now carried by wild deer in North America and the various ranges of species that may ingest CWD prions, such as birds or other small animals feeding on carcasses, it is very hard to estimate what the species barriers may or may not be, including the transmission to humans. Therefore, CWD puts certain populations at higher risk, such as the aboriginal community who rely on cervid meat as a major food source. PrioNet, in partnership with the Alberta Prion Research Institute, is supporting research aimed at gaining new scientific knowledge to control CWD. One focus is the ecology of CWD transmission among wild deer, pursued through population genetics and radiotelemetry approaches. Another is the detection and destruction of prions in the environment, and a third is vaccination against CWD. Overall, CWD poses the risk for huge economic, ecological and human health costs and PrioNet aims to be a part of the solution for the management, control, and demise of CWD in North America. •


http://www.prionetcanada.ca/files/PrioNews_Issue15-ENG804.pdf


Friday, January 15, 2010

Sixteen Additional Deer Test Positive for Chronic Wasting Disease In Hampshire County, West Virginia

http://chronic-wasting-disease.blogspot.com/2010/01/sixteen-additional-deer-test-positive.html


Thursday, January 21, 2010

Chronic Wasting Disease Found in White-tailed Deer in Virginia

http://chronic-wasting-disease.blogspot.com/2010/01/chronic-wasting-disease-found-in-white.html


CWD ILLINOIS UPDATE 2010 *Update January 6, 2010

http://chronic-wasting-disease.blogspot.com/2010/01/cwd-illinois-update-2010.html


Thursday, January 21, 2010 Kansas has more CWD cases

http://chronic-wasting-disease.blogspot.com/2010/01/kansas-has-more-cwd-cases.html


Sunday, December 06, 2009

Detection of Sub-Clinical CWD Infection in Conventional Test-Negative Deer Long after Oral Exposure to Urine and Feces from CWD+ Deer

http://chronic-wasting-disease.blogspot.com/2009/12/detection-of-sub-clinical-cwd-infection.html


Tuesday, June 16, 2009

Infectious Prions in Pre-Clinical Deer and Transmission of Chronic Wasting Disease Solely by Environmental Exposure

http://chronic-wasting-disease.blogspot.com/2009/06/infectious-prions-in-pre-clinical-deer.html


Friday, December 11, 2009

CWD, FECES, ORAL LESIONS, Aerosol and intranasal transmission

http://chronic-wasting-disease.blogspot.com/2009/12/cwd-feces-oral-lesions-aerosol-and.html


Wednesday, October 14, 2009

Detection of protease-resistant cervid prion protein in water from a CWD-endemic area

http://chronic-wasting-disease.blogspot.com/2009/10/detection-of-protease-resistant-cervid.html


AS THE CROW FLIES, SO DOES CWD

Sunday, November 01, 2009

American crows (Corvus brachyrhynchos) and potential spreading of CWD through feces of digested infectious carcases

http://chronic-wasting-disease.blogspot.com/2009/11/american-crows-corvus-brachyrhynchos.html


Sunday, October 04, 2009

CWD NEW MEXICO SPREADING SOUTH TO TEXAS 2009

http://chronic-wasting-disease.blogspot.com/2009/10/cwd-new-mexico-spreading-south-to-texas.html


Wednesday, January 07, 2009

CWD to tighten taxidermy rules Hunters need to understand regulations

http://chronic-wasting-disease.blogspot.com/2009/01/cwd-to-tighten-taxidermy-rules-hunters.html


Detection of Protease-Resistant Prion Protein in Water from a CWD-Endemic Area Posted by Terry S. Singeltary Sr. on December 4, 2009 at 11:42am

65

Detection of Protease-Resistant Prion Protein in Water from a CWD-Endemic Area

Tracy A. Nichols*1,2, Bruce Pulford1, Christy Wyckoff1,2, Crystal Meyerett1, Brady Michel1, Kevin Gertig3, Jean E. Jewell4, Glenn C. Telling5 and M.D. Zabel1 1Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA 2National Wildlife Research Center, Wildlife Services, United States Department of Agriculture, Fort Collins, Colorado, 80521, USA 3Fort Collins Water and Treatment Operations, Fort Collins, Colorado, 80521, USA 4 Department of Veterinary Sciences, Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming, 82070, USA 5Department of Microbiology, Immunology, Molecular Genetics and Neurology, Sanders Brown Center on Aging, University of Kentucky, Lexington, Kentucky, 40536, USA * Corresponding author- tracy.a.nichols@aphis.usda.gov

Chronic wasting disease (CWD) is the only known transmissible spongiform encephalopathy affecting free-ranging wildlife. Experimental and epidemiological data indicate that CWD can be transmitted horizontally and via blood and saliva, although the exact mode of natural transmission remains unknown. Substantial evidence suggests that prions can persist in the environment, implicating it as a potential prion reservoir and transmission vehicle. CWD- positive animals can contribute to environmental prion load via biological materials including saliva, blood, urine and feces, shedding several times their body weight in possibly infectious excreta in their lifetime, as well as through decomposing carcasses. Sensitivity limitations of conventional assays hamper evaluation of environmental prion loads in water. Here we show the ability of serial protein misfolding cyclic amplification (sPMCA) to amplify minute amounts of CWD prions in spiked water samples at a 1:1 x106 , and protease-resistant prions in environmental and municipal-processing water samples from a CWD endemic area. Detection of CWD prions correlated with increased total organic carbon in water runoff from melting winter snowpack. These data suggest prolonged persistence and accumulation of prions in the environment that may promote CWD transmission.

snip...

The data presented here demonstrate that sPMCA can detect low levels of PrPCWD in the environment, corroborate previous biological and experimental data suggesting long term persistence of prions in the environment2,3 and imply that PrPCWD accumulation over time may contribute to transmission of CWD in areas where it has been endemic for decades. This work demonstrates the utility of sPMCA to evaluate other environmental water sources for PrPCWD, including smaller bodies of water such as vernal pools and wallows, where large numbers of cervids congregate and into which prions from infected animals may be shed and concentrated to infectious levels.

snip...end...full text at ;

http://www.landesbioscience.com/


http://www.cwd-info.org/pdf/3rd_CWD_Symposium_utah.pdf


http://chronic-wasting-disease.blogspot.com/2009/08/third-international-cwd-symposium-july.html


http://chronic-wasting-disease.blogspot.com/2009/10/detection-of-protease-resistant-cervid.html



ALSO, NOTE MINERAL LICKS A POSSIBLE SOURCE AND TRANSMISSION MODE FOR CWD ;


http://chronic-wasting-disease.blogspot.com/2009/08/third-international-cwd-symposium-july.html


http://www.cwd-info.org/pdf/3rd_CWD_Symposium_utah.pdf


Thursday, September 10, 2009

Experimental oral transmission of CWD to red deer (Cervus elaphus elaphus): early detection and late stage distribution of protease-resistant protein

http://chronic-wasting-disease.blogspot.com/2009/09/experimental-oral-transmission-of.html


Thursday, September 24, 2009

Validation of Use of Rectoanal Mucosa-Associated Lymphoid Tissue for Immunohistochemical Diagnosis of Chronic Wasting Disease in White-Tailed Deer

http://chronic-wasting-disease.blogspot.com/2009/09/validation-of-use-of-rectoanal-mucosa.html



Sunday, April 12, 2009

CWD UPDATE Infection Studies in Two Species of Non-Human Primates and one Environmental reservoir infectivity study and evidence of two strains


http://chronic-wasting-disease.blogspot.com/2009/04/cwd-update-infection-studies-in-two.html



Wednesday, March 18, 2009

Detection of CWD Prions in Urine and Saliva of Deer by Transgenic Mouse Bioassay

http://chronic-wasting-disease.blogspot.com/2009/03/detection-of-cwd-prions-in-urine-and.html



Monday, July 13, 2009

Deer Carcass Decomposition and Potential Scavenger Exposure to Chronic Wasting Disease

http://chronic-wasting-disease.blogspot.com/2009/07/deer-carcass-decomposition-and.html



CWD, GAME FARMS, BAITING, AND POLITICS

http://chronic-wasting-disease.blogspot.com/2009/01/cwd-game-farms-baiting-and-politics.html



NOT only muscle, but now fat of CWD infected deer holds infectivity of the TSE (prion) agent. ...TSS

Monday, July 06, 2009

Prion infectivity in fat of deer with Chronic Wasting Disease

http://chronic-wasting-disease.blogspot.com/2009/07/prion-infectivity-in-fat-of-deer-with.html



Friday, February 20, 2009

Both Sides of the Fence: A Strategic Review of Chronic Wasting Disease

http://chronic-wasting-disease.blogspot.com/2009/02/both-sides-of-fence-strategic-review-of.html



Saturday, September 06, 2008

Chronic wasting disease in a Wisconsin white-tailed deer farm 79% INFECTION RATE

Contents: September 1 2008, Volume 20, Issue 5

snip...see full text ;


http://chronic-wasting-disease.blogspot.com/2008/11/commentary-crimes-hurt-essence-of.html



Sent: Friday, January 29, 2010 3:23 PM

Subject: 14th International Congress on Infectious Diseases H-type and L-type Atypical BSE January 2010 (special pre-congress edition)

18.173 page 189

Experimental Challenge of Cattle with H-type and L-type Atypical BSE

A. Buschmann1, U. Ziegler1, M. Keller1, R. Rogers2, B. Hills3, M.H. Groschup1. 1Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany, 2Health Canada, Bureau of Microbial Hazards, Health Products & Food Branch, Ottawa, Canada, 3Health Canada, Transmissible Spongiform Encephalopathy Secretariat, Ottawa, Canada

Background: After the detection of two novel BSE forms designated H-type and L-type atypical BSE the question of the pathogenesis and the agent distribution of these two types in cattle was fully open. From initial studies of the brain pathology, it was already known that the anatomical distribution of L-type BSE differs from that of the classical type where the obex region in the brainstem always displays the highest PrPSc concentrations. In contrast in L-type BSE cases, the thalamus and frontal cortex regions showed the highest levels of the pathological prion protein, while the obex region was only weakly involved.

Methods:We performed intracranial inoculations of cattle (five and six per group) using 10%brainstemhomogenates of the two German H- and L-type atypical BSE isolates. The animals were inoculated under narcosis and then kept in a free-ranging stable under appropriate biosafety conditions.At least one animal per group was killed and sectioned in the preclinical stage and the remaining animals were kept until they developed clinical symptoms. The animals were examined for behavioural changes every four weeks throughout the experiment following a protocol that had been established during earlier BSE pathogenesis studies with classical BSE.

Results and Discussion: All animals of both groups developed clinical symptoms and had to be euthanized within 16 months. The clinical picture differed from that of classical BSE, as the earliest signs of illness were loss of body weight and depression. However, the animals later developed hind limb ataxia and hyperesthesia predominantly and the head. Analysis of brain samples from these animals confirmed the BSE infection and the atypical Western blot profile was maintained in all animals. Samples from these animals are now being examined in order to be able to describe the pathogenesis and agent distribution for these novel BSE types. Conclusions: A pilot study using a commercially avaialble BSE rapid test ELISA revealed an essential restriction of PrPSc to the central nervous system for both atypical BSE forms. A much more detailed analysis for PrPSc and infectivity is still ongoing.


http://www.isid.org/14th_icid/


http://ww2.isid.org/Downloads/IMED2009_AbstrAuth.pdf


http://www.isid.org/publications/ICID_Archive.shtml



From: xxxx To: Terry Singeltary Sent: Saturday, December 05, 2009 9:09 AM Subject: 14th ICID - abstract accepted for 'International Scientific Exchange'

Your preliminary abstract number: 670

Dear Mr. Singeltary,

On behalf of the Scientific Committee, I am pleased to inform you that your abstract

'Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America update October 2009'

WAS accepted for inclusion in the INTERNATIONAL SCIENTIFIC EXCHANGE (ISE) section of the 14th International Congress on Infectious Diseases. Accordingly, your abstract will be included in the "Intl. Scientific Exchange abstract CD-rom" of the Congress which will be distributed to all participants.

Abstracts accepted for INTERNATIONAL SCIENTIFIC EXCHANGE are NOT PRESENTED in the oral OR poster sessions.

Your abstract below was accepted for: INTERNATIONAL SCIENTIFIC EXCHANGE

#0670: Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America update October 2009

Author: T. Singeltary; Bacliff, TX/US

Topic: Emerging Infectious Diseases Preferred type of presentation: International Scientific Exchange

This abstract has been ACCEPTED.

#0670: Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America update October 2009

Authors: T. Singeltary; Bacliff, TX/US

Title: Transmissible Spongiform encephalopathy (TSE) animal and human TSE in North America update October 2009

Body: Background

An update on atypical BSE and other TSE in North America. Please remember, the typical U.K. c-BSE, the atypical l-BSE (BASE), and h-BSE have all been documented in North America, along with the typical scrapie's, and atypical Nor-98 Scrapie, and to date, 2 different strains of CWD, and also TME. All these TSE in different species have been rendered and feed to food producing animals for humans and animals in North America (TSE in cats and dogs ?), and that the trading of these TSEs via animals and products via the USA and Canada has been immense over the years, decades.

Methods

12 years independent research of available data

Results

I propose that the current diagnostic criteria for human TSEs only enhances and helps the spreading of human TSE from the continued belief of the UKBSEnvCJD only theory in 2009. With all the science to date refuting it, to continue to validate this old myth, will only spread this TSE agent through a multitude of potential routes and sources i.e. consumption, medical i.e., surgical, blood, dental, endoscopy, optical, nutritional supplements, cosmetics etc.

Conclusion

I would like to submit a review of past CJD surveillance in the USA, and the urgent need to make all human TSE in the USA a reportable disease, in every state, of every age group, and to make this mandatory immediately without further delay. The ramifications of not doing so will only allow this agent to spread further in the medical, dental, surgical arena's. Restricting the reporting of CJD and or any human TSE is NOT scientific. Iatrogenic CJD knows NO age group, TSE knows no boundaries.

I propose as with Aguzzi, Asante, Collinge, Caughey, Deslys, Dormont, Gibbs, Gajdusek, Ironside, Manuelidis, Marsh, et al and many more, that the world of TSE Transmissible Spongiform Encephalopathy is far from an exact science, but there is enough proven science to date that this myth should be put to rest once and for all, and that we move forward with a new classification for human and animal TSE that would properly identify the infected species, the source species, and then the route.

Keywords: Transmissible Spongiform Encephalopathy Creutzfeldt Jakob Disease Prion



http://www.isid.org/14th_icid/



http://www.isid.org/publications/ICID_Archive.shtml



http://ww2.isid.org/Downloads/IMED2009_AbstrAuth.pdf



see full text ;

Friday, January 29, 2010

14th International Congress on Infectious Diseases H-type and L-type Atypical BSE January 2010 (special pre-congress edition)


http://bse-atypical.blogspot.com/2010/01/14th-international-congress-on.html



*** CJD USA RISING, with UNKNOWN PHENOTYPE ;

5 Includes 41 cases in which the diagnosis is pending, and 17 inconclusive cases; 6 Includes 46 cases with type determination pending in which the diagnosis of vCJD has been excluded.


http://www.cjdsurveillance.com/pdf/case-table.pdf



Friday, February 05, 2010

New Variant Creutzfelt Jakob Disease case reports United States 2010 A Review


http://vcjd.blogspot.com/2010/02/new-variant-creutzfelt-jakob-disease.html



Saturday, January 2, 2010

Human Prion Diseases in the United States January 1, 2010 ***FINAL***


http://prionunitusaupdate2008.blogspot.com/2010/01/human-prion-diseases-in-united-states.html



my comments to PLosone here ;


http://www.plosone.org/annotation/listThread.action?inReplyTo=info%3Adoi%2F10.1371%2Fannotation%2F04ce2b24-613d-46e6-9802-4131e2bfa6fd&root=info%3Adoi%2F10.1371%2Fannotation%2F04ce2b24-613d-46e6-9802-4131e2bfa6fd



Canada CJD

Referrals of Suspected CJD Reported by CJDSS1, 1997-2009²

Year of Reporting Numbers of Referrals

1997 4

1998 43

1999 63

2000 82

2001 101

2002 103

2003 75

2004 90

2005 96

2006 78

2007 101

2008 100

2009 31

Total 967

1CJD-SS began in April 1998

2Data before April 1998 are retrospective and partial, data from 1999 to 2007 are complete, and data for 2008 and 2009 are provisional


http://www.nml-lnm.gc.ca/cjd-mcj/cjdss-ssmcj/pdf/refs0409-eng.pdf


http://www.nml-lnm.gc.ca/cjd-mcj/cjdss-ssmcj/stats-eng.htm



There is one report of a possible cluster of CJD cases in Canada; between April 1989 and October 1990, six cases were reported in the province of Ontario, from a population of 9.5 million (1986 census figure). Two of the patients had come from areas of Czechoslovakia with a high incidence of familial-type disease, but no other risk factors were associated with these cases (7).

In conclusion, the epidemiology of CJD in Canada is not well defined, as current data sources are limited to aggregated mortality data and the annual total case numbers are small. However, several projects have been initiated to provide further information on the transmission of the disease, including an examination of death certificates to identify space/time clustering, active surveillance for CJD and new variant CJD, and a case control study of CJD and blood transfusion.

Elizabeth Stratton, Maura N. Ricketts, and Paul R. Gully Laboratory Centre for Disease Control, Health Canada,Ottawa, Ontario, Canada


http://www.cdc.gov/ncidod/EID/vol3no1/stratton.htm



Canada's first vCJD victim likely acquired disease in Britain, officials say Robert Roos News Editor

Aug 9, 2002 (CIDRAP News) – A Saskatchewan man who died earlier this summer was Canada's first victim of variant Creutzfeldt-Jakob disease (vCJD), but he probably acquired the disease in the United Kingdom, Canadian health officials announced yesterday.

Test results received from British experts this week confirmed earlier findings that the man had the first known case of vCJD in Canada, according to a news release from the Saskatchewan provincial government in Regina.

The man, whose name and hometown were not disclosed, probably contracted the disease while living and visiting in the UK in the 1980s and 1990s, said Dr. Ross Findlater, Saskatchewan's chief medical health officer. "It is highly unlikely that the case originated in Canada and just as unlikely that it was passed on to anyone in Canada," he said. "Based on our knowledge of this case, there is no reason to believe it is connected to Canadian livestock or the Canadian food supply."

Variant CJD is associated with eating beef from cattle infected with bovine spongiform encephalopathy (BSE), or mad cow disease. BSE was widespread in British cattle herds in the 1980s and early 1990s, and there have been 115 deaths due to definite or probable cases of vCJD, according to the UK Creutzfeldt-Jakob Disease Surveillance Unit in Edinburgh, Scotland.

One probable case of vCJD has been reported in the United States, in a female British citizen who was living in Florida when the case was announced last April. Officials said her case, too, was probably acquired in the UK. Her status was unclear at this writing; a telephone query to the Centers for Disease Control and Prevention was not answered in time. vCJD can be definitively diagnosed only by examination of brain tissue after death.

The then-suspected case of vCJD in the Saskatchewan man was reported to Canada's CJD Surveillance System last April, according to a Health Canada news release. The man, who was younger than 50, ate processed meat products while in the UK, and such products pose a high risk of BSE transmission if they come from infected cattle, Health Canada reported. The man ate very little beef after coming to Canada in the early 1990s, and he had not eaten deer or elk meat, according to the statement.

The man did not donate blood in Canada, but he did undergo a "medical procedure" that created a very slight risk of transmission of the disease to other patients through exposure to a device used in the procedure, officials said. Consequently, health officials were notifying people who were exposed to the device. The procedure was done before the man's diagnosis was suspected, according to Health Canada.

A report in the online edition of the Saskatoon, Sask., StarPhoenix said the procedure was an endoscopic examination conducted 4 months before the man died. The newspaper said the man died at St. Paul's Hospital in Saskatoon.

In the Saskatchewan news release, Dr. Steven Whitehead, deputy medical health officer for the Saskatoon region, noted that there is a theoretical risk that vCJD can be spread by medical equipment even after it has been thoroughly disinfected. "So out of an abundance of caution, Regional Health Authorty #6 . . . is contacting 71 people who may have been exposed to the same piece of equipment as the deceased while at the hospital," he said.

Whitehead called the risk of disease transmission "extremely minute," but said patients have a right to know about it. "Many of these patients have already been contacted, and we expect to reach the others in the next few days," he added.

Health Canada said the hospital has stopped using the devices that were used in the procedure on the vCJD patient. In addition, the hospital will advise patients who were exposed to the devices not to donate blood, organs, or tissues, the agency said. "However, if any of these individuals have donated blood since their procedure, their blood components that have not been pooled will be retrieved and destroyed. If any blood components donated by these individuals have been pooled, the theoretical and remote risk of CJD transmission does not merit further action," the statement said.

The agency said the victim's family members and healthcare providers are not at risk because vCJD is not spread through personal contact.

"Because the disease has a long incubation period, it was expected that a case of variant CJD would be diagnosed in Canada several years after a person acquired the disease while staying in the UK," the Health Canada statement said.

See also:

Saskatchewan government news release http://www.gov.sk.ca/newsrel/2002/08/08-636.html



Health Canada news release http://www.phac-aspc.gc.ca/cjd-mcj/vcjd-ca_e.html



http://www.cidrap.umn.edu/cidrap/content/other/bse/news/canadacjd.html



CWD Update 95 January 21, 2010


http://wildlifedisease.nbii.gov/documents/CWD%20Updates/update%2095.pdf



also see ;


http://chronic-wasting-disease.blogspot.com/




TSS

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